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Database: UniProt
Entry: A0A182DYK2_ONCOC
LinkDB: A0A182DYK2_ONCOC
Original site: A0A182DYK2_ONCOC 
ID   A0A182DYK2_ONCOC        Unreviewed;       458 AA.
AC   A0A182DYK2;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   05-JUN-2019, entry version 14.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:VDK62782.1, ECO:0000313|WBParaSite:nOo.2.0.1.t00751-RA};
GN   ORFNames=NOO_LOCUS751 {ECO:0000313|EMBL:VDK62782.1};
OS   Onchocerca ochengi (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX   NCBI_TaxID=42157 {ECO:0000313|Proteomes:UP000077448, ECO:0000313|WBParaSite:nOo.2.0.1.t00751-RA};
RN   [1] {ECO:0000313|Proteomes:UP000077448, ECO:0000313|WBParaSite:nOo.2.0.1.t00751-RA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22919073; DOI=10.1101/gr.138420.112;
RA   Darby A.C., Armstrong S.D., Bah G.S., Kaur G., Hughes M.A., Kay S.M.,
RA   Koldkaer P., Rainbow L., Radford A.D., Blaxter M.L., Tanya V.N.,
RA   Trees A.J., Cordaux R., Wastling J.M., Makepeace B.L.;
RT   "Analysis of gene expression from the Wolbachia genome of a filarial
RT   nematode supports both metabolic and defensive roles within the
RT   symbiosis.";
RL   Genome Res. 22:2467-2477(2012).
RN   [2] {ECO:0000313|WBParaSite:nOo.2.0.1.t00751-RA}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [3] {ECO:0000313|EMBL:VDK62782.1, ECO:0000313|Proteomes:UP000271087}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; UYRW01000080; VDK62782.1; -; Genomic_DNA.
DR   WBParaSite; nOo.2.0.1.t00751-RA; nOo.2.0.1.t00751-RA; nOo.2.0.1.g00751.
DR   Proteomes; UP000077448; Unassembled WGS sequence.
DR   Proteomes; UP000271087; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000077448,
KW   ECO:0000313|Proteomes:UP000271087};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000077448};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     72     93       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    145    170       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       35    175       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      182    355       IRK_C. {ECO:0000259|Pfam:PF17655}.
SQ   SEQUENCE   458 AA;  52561 MW;  7B0A98F069ED5AE3 CRC64;
     MECEDTLMTS DNRERPSRFF KTPRIGSRRI RNRLVQKGGI CNISLVNVPK QRRKYFSDIF
     TTVIEIRWRW TLLFFATSFI ASWTIFFSVY YFIITIHGDL EHVNDPNWTP CIMNANSKTN
     IFLFSFTTQT TIGYGFRYPT SECPLIIITM CLQFMVGVMC HTLMTGVIFA KLARPIKRAA
     TIIFSKNAVI CMRDGKLCLL FRVGDMRKSS LAEAHVRLQM IKKCITYEGE LLPFHQFDMD
     VGYDTGLDRV FVIWPITVCH EIDENSPLYE VSKENLRTAR FEIIAILEGV VESVGSTTQA
     RTSYLPNEIL WGKRFEKLVT YQRDNGEYRI DFEKFHNVYD VDTPPCSAKE LDKMRDLGLK
     PENAYQIAPD LNDNSAGSSP VIAIHPKGSS PRLSVLLSKG DNGTLRHLEK VETDDEDNDQ
     TIHVDVGLQH KRSLLTHAQS SDLLARHKQS VRRGPDLF
//
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