ID A0A182DYQ6_ONCOC Unreviewed; 567 AA.
AC A0A182DYQ6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Gamma-glutamyltranspeptidase 1 {ECO:0000313|WBParaSite:nOo.2.0.1.t00807-RA};
GN ORFNames=NOO_LOCUS807 {ECO:0000313|EMBL:VDK62880.1};
OS Onchocerca ochengi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=42157 {ECO:0000313|Proteomes:UP000077448, ECO:0000313|WBParaSite:nOo.2.0.1.t00807-RA};
RN [1] {ECO:0000313|Proteomes:UP000077448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22919073; DOI=10.1101/gr.138420.112;
RA Darby A.C., Armstrong S.D., Bah G.S., Kaur G., Hughes M.A., Kay S.M.,
RA Koldkaer P., Rainbow L., Radford A.D., Blaxter M.L., Tanya V.N.,
RA Trees A.J., Cordaux R., Wastling J.M., Makepeace B.L.;
RT "Analysis of gene expression from the Wolbachia genome of a filarial
RT nematode supports both metabolic and defensive roles within the
RT symbiosis.";
RL Genome Res. 22:2467-2477(2012).
RN [2] {ECO:0000313|WBParaSite:nOo.2.0.1.t00807-RA}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [3] {ECO:0000313|EMBL:VDK62880.1, ECO:0000313|Proteomes:UP000271087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYRW01000087; VDK62880.1; -; Genomic_DNA.
DR STRING; 42157.A0A182DYQ6; -.
DR WBParaSite; nOo.2.0.1.t00807-RA; nOo.2.0.1.t00807-RA; nOo.2.0.1.g00807.
DR Proteomes; UP000077448; Unassembled WGS sequence.
DR Proteomes; UP000271087; Unassembled WGS sequence.
DR GO; GO:0036374; F:glutathione hydrolase activity; IEA:InterPro.
DR GO; GO:0006751; P:glutathione catabolic process; IEA:InterPro.
DR Gene3D; 1.10.246.130; -; 1.
DR Gene3D; 3.60.20.40; -; 1.
DR InterPro; IPR043138; GGT_lsub_C.
DR InterPro; IPR000101; GGT_peptidase.
DR InterPro; IPR043137; GGT_ssub.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR PANTHER; PTHR11686; GAMMA GLUTAMYL TRANSPEPTIDASE; 1.
DR PANTHER; PTHR11686:SF17; PROTEIN CBG05566; 1.
DR Pfam; PF01019; G_glu_transpept; 1.
DR PRINTS; PR01210; GGTRANSPTASE.
DR SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
DR PROSITE; PS00462; G_GLU_TRANSPEPTIDASE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000271087}.
FT ACT_SITE 374
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR600101-1"
SQ SEQUENCE 567 AA; 62678 MW; 14F5E3B3EB70C5AF CRC64;
MAKKKLHGGY SWPPPSYSYM GEYKRAAVTC DHGLCSEIGR NILLRGGNAV DASIASLFCL
GVTNPQSSGI GGGFIMTLYN RTKEKCIVID ARETAPEKAH RNMFINDEFG SKYGFRAIAT
PGEIAGYWLA FKRFGSGQVS WYDLIKPSID LCRYGVPVSK YLAYVLSVKE KHFETLPSMQ
SWINNATNKV FVAGDIIKRP ELAKTLERLA LSSDPEELFY RGDIAKTLVK EIQKNGGIIT
LNDFAQFKPT VHEHPLVNDH FSDNLAMCGP PPPSSFASTQ LIISLMARFY GPKTNKEVLQ
RGPLFYHRFI EAQKFAYAQR TLMGDEAFVT EAKGLAKNMT TKAYADWVFS RMRNTTQPTE
YYGGIRKQLN DHGTSHVSVL DSMGNGVSST STVNRWFGAV VQSVDLGIVF NDEMDDFSTP
GMANGFGFAP SESNFIEPKK KPMSSMSPMI IYNTKTGKVV MVAGASGGSK IISVLAKSIV
RVLFFNETIK EAIDAPALHN QFTPDITQFE DVVPKALMND LTRKFGQTFK KTTGFEGIAQ
GIVVGEDGTI YANGDYRRQT DMHPGGY
//
