ID A0A182E0X6_ONCOC Unreviewed; 650 AA.
AC A0A182E0X6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Transcription initiation factor TFIID subunit 5 {ECO:0000256|ARBA:ARBA00044130};
GN ORFNames=NOO_LOCUS1607 {ECO:0000313|EMBL:VDK64528.1};
OS Onchocerca ochengi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=42157 {ECO:0000313|Proteomes:UP000077448, ECO:0000313|WBParaSite:nOo.2.0.1.t01607-RA};
RN [1] {ECO:0000313|Proteomes:UP000077448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22919073; DOI=10.1101/gr.138420.112;
RA Darby A.C., Armstrong S.D., Bah G.S., Kaur G., Hughes M.A., Kay S.M.,
RA Koldkaer P., Rainbow L., Radford A.D., Blaxter M.L., Tanya V.N.,
RA Trees A.J., Cordaux R., Wastling J.M., Makepeace B.L.;
RT "Analysis of gene expression from the Wolbachia genome of a filarial
RT nematode supports both metabolic and defensive roles within the
RT symbiosis.";
RL Genome Res. 22:2467-2477(2012).
RN [2] {ECO:0000313|WBParaSite:nOo.2.0.1.t01607-RA}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [3] {ECO:0000313|EMBL:VDK64528.1, ECO:0000313|Proteomes:UP000271087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the WD repeat TAF5 family.
CC {ECO:0000256|ARBA:ARBA00009435}.
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DR EMBL; UYRW01000211; VDK64528.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182E0X6; -.
DR STRING; 42157.A0A182E0X6; -.
DR WBParaSite; nOo.2.0.1.t01607-RA; nOo.2.0.1.t01607-RA; nOo.2.0.1.g01607.
DR Proteomes; UP000077448; Unassembled WGS sequence.
DR Proteomes; UP000271087; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR CDD; cd08044; TAF5_NTD2; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.25.40.500; TFIID subunit TAF5, NTD2 domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR006594; LisH.
DR InterPro; IPR007582; TFIID_NTD2.
DR InterPro; IPR037264; TFIID_NTD2_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19879:SF1; CANNONBALL-RELATED; 1.
DR PANTHER; PTHR19879; TRANSCRIPTION INITIATION FACTOR TFIID; 1.
DR Pfam; PF04494; TFIID_NTD2; 1.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF160897; Taf5 N-terminal domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50896; LISH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000271087};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 89..203
FT /note="TFIID subunit TAF5 NTD2"
FT /evidence="ECO:0000259|Pfam:PF04494"
FT REPEAT 394..435
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 435..476
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 477..518
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 519..552
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 260..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..283
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 650 AA; 72482 MW; EEC5945BE53B0852 CRC64;
MKDEIVYMRD VHSKKSKFGI PKKPLKTTDR YALDMDGDIF EQPLTAESLQ QILAFFKKNG
LTESEETLSR EAAAVLRLSK DGVDSDISND AVMREFSTLL THIDSSFDNF RAELSALIFP
VFAHLYIQLI AEGHSLQAAL FSEKFSRHIP SMYEEQTKLL TRISTHSQAA NHALVQALTK
NQFVVRISKS AIKQLEPFLT RNSIVRDVMR DHLHIEAIDG SRTKSATEAS LGGILGQVSK
QERRHKMFYG TIKEDFSTQL GLEKKRPKIK ERSDNKKKDA NGPSSDRIPL PAAIEKRYMK
ESGKKMRISV DTPPSVCLYT VLNSPGGLTA SDIAEDSGAL ALGFGNSRIQ VHALNEENFR
PYKKIDQLEL IEQEAEDALD QVYDDSEAST SLTFQGHNGP VYSLSFSPDK RLLLSSSRDG
TVRLWSLAIR SNVVVYRHAA PIWEVQFCPR SYYFATGSAD GAAMLWTTDR LQPLRIFSDA
LSDVTCIDFH PNCNYFAGGS DDRYVRVWDV LSGTCVRCFA GHKGSIRGLK ISPCGRYLAS
VGSEGSLVLW DMALQKMVCM QDVAAVPYKI PVEFSRDGGA LVVARTDSAL SFYSVDTVTA
HSSSQDHLNN DPKINPSGFH LYSYATKNTS IINLHFTRRN LVLAVGAFRQ
//
