ID A0A182E1A2_ONCOC Unreviewed; 811 AA.
AC A0A182E1A2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=DNA helicase {ECO:0000313|WBParaSite:nOo.2.0.1.t01736-RA};
GN ORFNames=NOO_LOCUS1736 {ECO:0000313|EMBL:VDK64796.1};
OS Onchocerca ochengi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=42157 {ECO:0000313|Proteomes:UP000077448, ECO:0000313|WBParaSite:nOo.2.0.1.t01736-RA};
RN [1] {ECO:0000313|Proteomes:UP000077448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22919073; DOI=10.1101/gr.138420.112;
RA Darby A.C., Armstrong S.D., Bah G.S., Kaur G., Hughes M.A., Kay S.M.,
RA Koldkaer P., Rainbow L., Radford A.D., Blaxter M.L., Tanya V.N.,
RA Trees A.J., Cordaux R., Wastling J.M., Makepeace B.L.;
RT "Analysis of gene expression from the Wolbachia genome of a filarial
RT nematode supports both metabolic and defensive roles within the
RT symbiosis.";
RL Genome Res. 22:2467-2477(2012).
RN [2] {ECO:0000313|WBParaSite:nOo.2.0.1.t01736-RA}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [3] {ECO:0000313|EMBL:VDK64796.1, ECO:0000313|Proteomes:UP000271087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYRW01000235; VDK64796.1; -; Genomic_DNA.
DR STRING; 42157.A0A182E1A2; -.
DR WBParaSite; nOo.2.0.1.t01736-RA; nOo.2.0.1.t01736-RA; nOo.2.0.1.g01736.
DR Proteomes; UP000077448; Unassembled WGS sequence.
DR Proteomes; UP000271087; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR CDD; cd18666; CD1_tandem_CHD1-2_like; 1.
DR CDD; cd17993; DEXHc_CHD1_2; 1.
DR Gene3D; 2.40.50.40; -; 2.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR023779; Chromodomain_CS.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45623:SF14; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR45623; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED; 1.
DR Pfam; PF00385; Chromo; 2.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00298; CHROMO; 2.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00598; CHROMO_1; 2.
DR PROSITE; PS50013; CHROMO_2; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022806};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022806};
KW Reference proteome {ECO:0000313|Proteomes:UP000271087}.
FT DOMAIN 280..365
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT DOMAIN 399..464
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT DOMAIN 507..694
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT REGION 1..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..103
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..181
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..251
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 811 AA; 93156 MW; 6F839DCA99349749 CRC64;
MSSSSVTSDS EFTAESSGSE STSDHQRSES ISDHQETITV DLTARQESDT NADGITIVGE
SFKEGNDGEI SSIGSSKSDS DTKDGESDTS DSKNSENGEF NVYERKSDSV FSAESGDGEV
ATIKKKRGIK ITDETRKFLE DENILRRSSR QRKETTDSNA EKGTEKTVKK AGKRQLPQSG
EDETSDDESP SEITLARKTY QKFKKSQAKK RSRKHNISSD DDSGGIRPTR QSKIDGEKNR
INYRDISSDE EINSDDVLEW DEGDKVGGDG SADHNTSGNE TIEKILRHRA GYPGATGAST
TCYNVEDKGD PNVKLAENGN EMELERQYLI KWLGWSHLHN TWESENSLKL CNAKGLKKID
NYMKRLRDIE EWKITADKEY IEFFDCEQQM NDELNEQYKI IERVIAHQIS RNQGETEGTE
YFVKWCGLPY SECTWEEEHL IARQFKDKID AYYDRRDNGK VPNKHCPVLR KRPRFEKLND
IPEFLQRKDD PEHELRDYQL EGVNWMLHAW TKENSCILAD EMGLGKTIQS ISFLSVLYHK
YQLYGPFLVV VPLSTMASWQ HEFETWAPDL NVVTYVGDVT SRDLIRQFEI YVQSAKRLKV
NVVLTTYEIL LKDKASFPLL LRVGINFVYL QSFLGSFEWA VLAVDEAHRL KNDESLLYRS
LFEFTTNHRL LITGTPLQNS LKELWALLHF IMPDKFDSWT EFEAEHHDSD HKTIASLHRK
LQPFLLRRVK KDVEKSLPAK VEQILRVDMT AQQKQYYKWI LTKNYKELSK GVKGSINGFV
NLVMELKKCC NHASLVRSYD QSEESADARL Q
//
