ID A0A182E1W8_ONCOC Unreviewed; 350 AA.
AC A0A182E1W8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Deoxyribonuclease II {ECO:0000313|WBParaSite:nOo.2.0.1.t01960-RA};
GN ORFNames=NOO_LOCUS1960 {ECO:0000313|EMBL:VDK65270.1};
OS Onchocerca ochengi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=42157 {ECO:0000313|Proteomes:UP000077448, ECO:0000313|WBParaSite:nOo.2.0.1.t01960-RA};
RN [1] {ECO:0000313|Proteomes:UP000077448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22919073; DOI=10.1101/gr.138420.112;
RA Darby A.C., Armstrong S.D., Bah G.S., Kaur G., Hughes M.A., Kay S.M.,
RA Koldkaer P., Rainbow L., Radford A.D., Blaxter M.L., Tanya V.N.,
RA Trees A.J., Cordaux R., Wastling J.M., Makepeace B.L.;
RT "Analysis of gene expression from the Wolbachia genome of a filarial
RT nematode supports both metabolic and defensive roles within the
RT symbiosis.";
RL Genome Res. 22:2467-2477(2012).
RN [2] {ECO:0000313|WBParaSite:nOo.2.0.1.t01960-RA}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [3] {ECO:0000313|EMBL:VDK65270.1, ECO:0000313|Proteomes:UP000271087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNase II family.
CC {ECO:0000256|ARBA:ARBA00007527}.
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DR EMBL; UYRW01000277; VDK65270.1; -; Genomic_DNA.
DR STRING; 42157.A0A182E1W8; -.
DR WBParaSite; nOo.2.0.1.t01960-RA; nOo.2.0.1.t01960-RA; nOo.2.0.1.g01960.
DR Proteomes; UP000077448; Unassembled WGS sequence.
DR Proteomes; UP000271087; Unassembled WGS sequence.
DR GO; GO:0004531; F:deoxyribonuclease II activity; IEA:InterPro.
DR CDD; cd09120; PLDc_DNaseII_1; 1.
DR InterPro; IPR004947; DNase_II.
DR PANTHER; PTHR10858:SF24; CELL DEATH-RELATED NUCLEASE 6; 1.
DR PANTHER; PTHR10858; DEOXYRIBONUCLEASE II; 1.
DR Pfam; PF03265; DNase_II; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000271087};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..350
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041047518"
SQ SEQUENCE 350 AA; 40376 MW; 0B10C2D63CBBE019 CRC64;
MFLKISLLFS LILHACIALS FQCRDQENRD VDWFIFYKIG RIKKSTIKSV RNGSAFLYMD
VNHHQWSLSA VDIYNSNQAI GYTLQQYYDA RNNSEVFSIM YNDEFPYPNN DTLSGSSGHT
KGVVVFGKSN GFWFLHSVPK FPRNDTYEYP VTGLHYGQMG LCLSMSYSQL HKIAIQLYYN
RLFIYSKKLP AQMAENIPLL VKVMSNKYQR TAPYVSRVVI YSTAGHLYFD LVAPSIKSSL
KTETWQHETS RNKNLRSWCR NYSPFKVLDV KKVILPFNIT FPNALDHSKF AVATFDAHKI
PVPWICIGDI NRQERQLLRA GGTMCFANSE VHAIYTSMVS NYWPCINTNS
//
