ID A0A182E287_ONCOC Unreviewed; 372 AA.
AC A0A182E287;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=PPM-type phosphatase domain-containing protein {ECO:0000313|WBParaSite:nOo.2.0.1.t02084-RA};
GN ORFNames=NOO_LOCUS2084 {ECO:0000313|EMBL:VDK65540.1};
OS Onchocerca ochengi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=42157 {ECO:0000313|Proteomes:UP000077448, ECO:0000313|WBParaSite:nOo.2.0.1.t02084-RA};
RN [1] {ECO:0000313|Proteomes:UP000077448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22919073; DOI=10.1101/gr.138420.112;
RA Darby A.C., Armstrong S.D., Bah G.S., Kaur G., Hughes M.A., Kay S.M.,
RA Koldkaer P., Rainbow L., Radford A.D., Blaxter M.L., Tanya V.N.,
RA Trees A.J., Cordaux R., Wastling J.M., Makepeace B.L.;
RT "Analysis of gene expression from the Wolbachia genome of a filarial
RT nematode supports both metabolic and defensive roles within the
RT symbiosis.";
RL Genome Res. 22:2467-2477(2012).
RN [2] {ECO:0000313|WBParaSite:nOo.2.0.1.t02084-RA}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [3] {ECO:0000313|EMBL:VDK65540.1, ECO:0000313|Proteomes:UP000271087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PP2C family.
CC {ECO:0000256|RuleBase:RU003465}.
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DR EMBL; UYRW01000302; VDK65540.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182E287; -.
DR STRING; 42157.A0A182E287; -.
DR WBParaSite; nOo.2.0.1.t02084-RA; nOo.2.0.1.t02084-RA; nOo.2.0.1.g02084.
DR Proteomes; UP000077448; Unassembled WGS sequence.
DR Proteomes; UP000271087; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR000222; PP2C_BS.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR13832:SF565; AT28366P-RELATED; 1.
DR PANTHER; PTHR13832; PROTEIN PHOSPHATASE 2C; 1.
DR Pfam; PF00481; PP2C; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS01032; PPM_1; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003465};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912,
KW ECO:0000256|RuleBase:RU003465};
KW Reference proteome {ECO:0000313|Proteomes:UP000271087}.
FT DOMAIN 13..276
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
SQ SEQUENCE 372 AA; 40813 MW; 5C7BEFBAE02013FC CRC64;
MGQTLSEPVT TKETASCANP FYKIDMEDAH IHLLAVPDDT QAAFFAVYDG HGGAKVSQYA
GIHLHKLIAT NTHYVEGNIK EAIKQGFLAL DEKMRKDEEM RDDMSGTTAV IVLIKDKKIY
CGNVGDSRAV ACVSGAAHPL SFDHKPANEN EARRIVAAGG WVEFNRVNGN LALSRALGDF
AFKKNEHKSP EEQIVTACPD VTVCDLTYDH EFIILACDGI WDVMSNQEVV EFCRDRLAAG
CEPEAICEEL LSRCLAPDCQ MGGLGCDNMT AVLVCLLQED TPEAYIARCS RKPVESAAGD
ATSLDSETYV TPQPSPVEIE PNEELLEQQQ DSVSKLNITV TSEQEFADNE KSSREYIIHL
EKTKSSNENT VS
//
