ID A0A182E687_ONCOC Unreviewed; 378 AA.
AC A0A182E687;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Battenin {ECO:0000256|RuleBase:RU361113};
GN ORFNames=NOO_LOCUS3523 {ECO:0000313|EMBL:VDK69472.1};
OS Onchocerca ochengi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=42157 {ECO:0000313|Proteomes:UP000077448, ECO:0000313|WBParaSite:nOo.2.0.1.t03523-RA};
RN [1] {ECO:0000313|Proteomes:UP000077448, ECO:0000313|WBParaSite:nOo.2.0.1.t03523-RA}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22919073; DOI=10.1101/gr.138420.112;
RA Darby A.C., Armstrong S.D., Bah G.S., Kaur G., Hughes M.A., Kay S.M.,
RA Koldkaer P., Rainbow L., Radford A.D., Blaxter M.L., Tanya V.N.,
RA Trees A.J., Cordaux R., Wastling J.M., Makepeace B.L.;
RT "Analysis of gene expression from the Wolbachia genome of a filarial
RT nematode supports both metabolic and defensive roles within the
RT symbiosis.";
RL Genome Res. 22:2467-2477(2012).
RN [2] {ECO:0000313|WBParaSite:nOo.2.0.1.t03523-RA}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [3] {ECO:0000313|EMBL:VDK69472.1, ECO:0000313|Proteomes:UP000271087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Lysosome membrane
CC {ECO:0000256|RuleBase:RU361113}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU361113}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the battenin family.
CC {ECO:0000256|ARBA:ARBA00007467, ECO:0000256|RuleBase:RU361113}.
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DR EMBL; UYRW01000680; VDK69472.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182E687; -.
DR STRING; 42157.A0A182E687; -.
DR WBParaSite; nOo.2.0.1.t03523-RA; nOo.2.0.1.t03523-RA; nOo.2.0.1.g03523.
DR Proteomes; UP000077448; Unassembled WGS sequence.
DR Proteomes; UP000271087; Unassembled WGS sequence.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR003492; Battenin_disease_Cln3.
DR InterPro; IPR018460; Battenin_disease_Cln3_subgr.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR10981; BATTENIN; 1.
DR PANTHER; PTHR10981:SF0; BATTENIN; 1.
DR Pfam; PF02487; CLN3; 2.
DR PIRSF; PIRSF015974; CLN3_BTN1; 2.
DR PRINTS; PR01315; BATTENIN.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Lysosome {ECO:0000256|RuleBase:RU361113};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361113};
KW Reference proteome {ECO:0000313|Proteomes:UP000271087};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361113};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361113}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361113"
FT TRANSMEM 76..94
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361113"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361113"
FT TRANSMEM 132..152
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361113"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361113"
FT TRANSMEM 190..207
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361113"
FT TRANSMEM 306..329
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361113"
FT TRANSMEM 350..373
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361113"
SQ SEQUENCE 378 AA; 41615 MW; 4D2E65DB732BA220 CRC64;
MPTVEGASSG HGSSRNQFAF WILGLCNNFA YVIMLSAAED ILSVEDGPKA SSKSIDDPCQ
SSIVHRQCQP LSTGSVLLAN IIPSLVVKMF YPFVMHRIPF GMRHLFTVLL QISSFLVVAF
SQNIPMGLTG VALASIGAGI GEVTFLSLTT YFHNNVVGAW SSGTGGAGIF GSFAYAMLTD
MHMLGLKPRN ALLLMLIIPL IFAFVYFDDV AFVLFIDNYN DSGGELVPDI EQQSFKNKLI
IAKPLILKYM LPFAVVYFAE YFINQGLLEL LIFDCGHSFG IGQHGQYRWY QIINAIFLFW
DALKQFIPHV IVVFIIVFYE GLLGGAAYVN IFRLLHKSTP VEGREFSLSF VSMSDSFGIV
CAGFLAIPAH NFICGMPV
//
