ID A0A182E985_ONCOC Unreviewed; 669 AA.
AC A0A182E985;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=BPI2 domain-containing protein {ECO:0000313|WBParaSite:nOo.2.0.1.t04595-RA};
GN ORFNames=NOO_LOCUS4595 {ECO:0000313|EMBL:VDK73696.1};
OS Onchocerca ochengi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=42157 {ECO:0000313|Proteomes:UP000077448, ECO:0000313|WBParaSite:nOo.2.0.1.t04595-RA};
RN [1] {ECO:0000313|Proteomes:UP000077448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22919073; DOI=10.1101/gr.138420.112;
RA Darby A.C., Armstrong S.D., Bah G.S., Kaur G., Hughes M.A., Kay S.M.,
RA Koldkaer P., Rainbow L., Radford A.D., Blaxter M.L., Tanya V.N.,
RA Trees A.J., Cordaux R., Wastling J.M., Makepeace B.L.;
RT "Analysis of gene expression from the Wolbachia genome of a filarial
RT nematode supports both metabolic and defensive roles within the
RT symbiosis.";
RL Genome Res. 22:2467-2477(2012).
RN [2] {ECO:0000313|WBParaSite:nOo.2.0.1.t04595-RA}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [3] {ECO:0000313|EMBL:VDK73696.1, ECO:0000313|Proteomes:UP000271087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
CC {ECO:0000256|ARBA:ARBA00007292}.
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DR EMBL; UYRW01001066; VDK73696.1; -; Genomic_DNA.
DR STRING; 42157.A0A182E985; -.
DR WBParaSite; nOo.2.0.1.t04595-RA; nOo.2.0.1.t04595-RA; nOo.2.0.1.g04595.
DR Proteomes; UP000077448; Unassembled WGS sequence.
DR Proteomes; UP000271087; Unassembled WGS sequence.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR InterPro; IPR017943; Bactericidal_perm-incr_a/b_dom.
DR InterPro; IPR032942; BPI/LBP/Plunc.
DR InterPro; IPR001124; Lipid-bd_serum_glycop_C.
DR InterPro; IPR017942; Lipid-bd_serum_glycop_N.
DR PANTHER; PTHR10504; BACTERICIDAL PERMEABILITY-INCREASING BPI PROTEIN-RELATED; 1.
DR PANTHER; PTHR10504:SF131; BPI2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01273; LBP_BPI_CETP; 1.
DR Pfam; PF02886; LBP_BPI_CETP_C; 2.
DR SMART; SM00328; BPI1; 1.
DR SMART; SM00329; BPI2; 1.
DR SUPFAM; SSF55394; Bactericidal permeability-increasing protein, BPI; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000271087}.
FT DOMAIN 38..266
FT /note="Lipid-binding serum glycoprotein N-terminal"
FT /evidence="ECO:0000259|SMART:SM00328"
FT DOMAIN 404..649
FT /note="Lipid-binding serum glycoprotein C-terminal"
FT /evidence="ECO:0000259|SMART:SM00329"
SQ SEQUENCE 669 AA; 74417 MW; BBA121DBB88B13A2 CRC64;
MAVSGKIIII SDYIVTFGNI IIISDFCGYI GFPGIKIRFN RNAFRYASSV IAQLLNQEIQ
NIQIPGYTQS LQEVNGYARL SHIMITNYQC PEHVALFPIS HNQIGLKIRN FALSVRGQLR
GQVTVLLPFS LCGTVCIDAR QISMYVQLSI ERNPHNNAPY IRMSKCSLTI GYLNIQINEG
GIIGFIINNI FRTKIISQAN ETIPGQICEM VPGLLDERVN SQLANIPQEI STSQVLPYVA
SLISRPKKLP DYCSSEICQL YQTTILSLTN KKLKSKAISI SGVPNIANLK QKAININKPL
MNLKHLNNDK LLNIVAIRLA DTTNNSQWEQ CANCDKKDNE ILSYYLDFVL NRIQTCASDL
ALSTYLLGSS TTNYDLTFDL AGEFSPNTQG GTPFGSPVLQ YPVSDSGRML DLLISDYMLN
TLLYHLHRKG IFSFRIGPEI PIVGDLLNLT CEIDFDLSVT QNENDLTTEK TSDSPHVRNK
RLTTTGTLLN LGICFGNIAP AIREKYPQKK VYIIIGTSRG PSIQFHTANN DTIVTDLMLD
GFIFLDGTTI QVGHLRIVNE FAITIQIIGN RIIGKAQVQR MEFVDVDETF GIPKEAFMNL
SDLARGILSN AINEKLANGF PIEMPRLGSP INLYNIHLQI IKHALFISTD IAIPSLVSNP
GYTGCFSYN
//
