ID A0A182EIN5_ONCOC Unreviewed; 439 AA.
AC A0A182EIN5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 13-SEP-2023, entry version 30.
DE SubName: Full=TFIIS N-terminal domain-containing protein {ECO:0000313|WBParaSite:nOo.2.0.1.t06046-RA, ECO:0000313|WBParaSite:nOo.2.0.1.t07967-RA};
GN ORFNames=NOO_LOCUS6046 {ECO:0000313|EMBL:VDK80689.1}, NOO_LOCUS7967
GN {ECO:0000313|EMBL:VDK87872.1};
OS Onchocerca ochengi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=42157 {ECO:0000313|Proteomes:UP000077448, ECO:0000313|WBParaSite:nOo.2.0.1.t07967-RA};
RN [1] {ECO:0000313|Proteomes:UP000077448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22919073; DOI=10.1101/gr.138420.112;
RA Darby A.C., Armstrong S.D., Bah G.S., Kaur G., Hughes M.A., Kay S.M.,
RA Koldkaer P., Rainbow L., Radford A.D., Blaxter M.L., Tanya V.N.,
RA Trees A.J., Cordaux R., Wastling J.M., Makepeace B.L.;
RT "Analysis of gene expression from the Wolbachia genome of a filarial
RT nematode supports both metabolic and defensive roles within the
RT symbiosis.";
RL Genome Res. 22:2467-2477(2012).
RN [2] {ECO:0000313|WBParaSite:nOo.2.0.1.t06046-RA, ECO:0000313|WBParaSite:nOo.2.0.1.t07967-RA}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [3] {ECO:0000313|EMBL:VDK80689.1, ECO:0000313|Proteomes:UP000271087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00649}.
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DR EMBL; UYRW01001774; VDK80689.1; -; Genomic_DNA.
DR EMBL; UYRW01003082; VDK87872.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182EIN5; -.
DR STRING; 42157.A0A182EIN5; -.
DR WBParaSite; nOo.2.0.1.t06046-RA; nOo.2.0.1.t06046-RA; nOo.2.0.1.g06046.
DR WBParaSite; nOo.2.0.1.t07967-RA; nOo.2.0.1.t07967-RA; nOo.2.0.1.g07967.
DR Proteomes; UP000077448; Unassembled WGS sequence.
DR Proteomes; UP000271087; Unassembled WGS sequence.
DR GO; GO:0070449; C:elongin complex; IEA:InterPro.
DR GO; GO:0006368; P:transcription elongation by RNA polymerase II; IEA:InterPro.
DR Gene3D; 6.10.250.3180; -; 1.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR010684; RNA_pol_II_trans_fac_SIII_A.
DR InterPro; IPR003617; TFIIS/CRSP70_N_sub.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR15141; TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3; 1.
DR PANTHER; PTHR15141:SF76; TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3; 1.
DR Pfam; PF06881; Elongin_A; 1.
DR Pfam; PF08711; Med26; 1.
DR SMART; SM00509; TFS2N; 1.
DR SUPFAM; SSF47676; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00649}; Reference proteome {ECO:0000313|Proteomes:UP000271087}.
FT DOMAIN 5..77
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT REGION 80..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..131
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 439 AA; 50345 MW; 9587E8A87E50572A CRC64;
MDDNEDIREK VEKYKRMLSC DSKIGHALKR LANINMTLDL LSETGVGKAV NQLRNHDQYG
TKAVQIVEKW KDMARSCGLK QRRKGYLSPS SEQEENHPKK SKKGNRREEK GSNNEQEVYN
NGDEVHHSKA KSSNDGLGNA CSGLSFADML ARADTAKPFK LKKMKTDCND WKSSKVDINY
KPSKVLNFEP IPKEHHTDVS GTVMMDTSMF KPRKSVRKIY AGRPKNDTAK EVPTLLNLCI
KVLIANINSI EEIGDTPYFI LKPVLEKCSP NQLCLIERRN PQLMEDSDEL WKRIVNRTFP
KCEPANKEKW RECYYRLCEE NERKLKLLST KITQHNREAT LPVKTALLAD AKAPREIRRR
QIRYGTQHAT HPLPSANEIS KARKEIFYKG NKEGLAHLPQ AIRNISSSLG SHSEKKKIVP
KKGILMIKTL RMLNVKRKR
//
