ID   A0A182F1P7_ANOAL        Unreviewed;       729 AA.
AC   A0A182F1P7;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:AALB000376-PA};
OS   Anopheles albimanus (New world malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7167 {ECO:0000313|EnsemblMetazoa:AALB000376-PA, ECO:0000313|Proteomes:UP000069272};
RN   [1] {ECO:0000313|EnsemblMetazoa:AALB000376-PA}
RP   IDENTIFICATION.
RC   STRAIN=STECLA/ALBI9_A {ECO:0000313|EnsemblMetazoa:AALB000376-PA};
RG   EnsemblMetazoa;
RL   Submitted (AUG-2022) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the ku80 family.
CC       {ECO:0000256|ARBA:ARBA00007726}.
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DR   AlphaFoldDB; A0A182F1P7; -.
DR   STRING; 7167.A0A182F1P7; -.
DR   EnsemblMetazoa; AALB000376-RA; AALB000376-PA; AALB000376.
DR   VEuPathDB; VectorBase:AALB000376; -.
DR   VEuPathDB; VectorBase:AALB20_029498; -.
DR   OrthoDB; 5884at2759; -.
DR   Proteomes; UP000069272; Chromosome 2L.
DR   GO; GO:0043564; C:Ku70:Ku80 complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0042162; F:telomeric DNA binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
DR   GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR   CDD; cd00873; KU80; 1.
DR   Gene3D; 1.10.1600.10; -; 1.
DR   Gene3D; 2.40.290.10; -; 1.
DR   Gene3D; 1.25.40.240; Ku, C-terminal domain; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR006164; Ku70/Ku80_beta-barrel_dom.
DR   InterPro; IPR024193; Ku80.
DR   InterPro; IPR036494; Ku_C_sf.
DR   InterPro; IPR005161; Ku_N.
DR   InterPro; IPR014893; Ku_PK_bind.
DR   InterPro; IPR016194; SPOC-like_C_dom_sf.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR12604; KU AUTOANTIGEN DNA HELICASE; 1.
DR   PANTHER; PTHR12604:SF4; X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5; 1.
DR   Pfam; PF02735; Ku; 1.
DR   Pfam; PF03731; Ku_N; 1.
DR   Pfam; PF08785; Ku_PK_bind; 1.
DR   SMART; SM00559; Ku78; 1.
DR   SUPFAM; SSF101420; C-terminal domain of Ku80; 1.
DR   SUPFAM; SSF100939; SPOC domain-like; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242}.
SQ   SEQUENCE   729 AA;  81179 MW;  E65AD59279CA4CE4 CRC64;
     MARVPKTGHM IVIDVGRSTS RSCGDQSFFE IAKECGIRLM GRNICSFPQD EVGLVLMGTD
     ETSNQQNTEH GSGYEHISEA CELKLPSWNT ARVLENKVLR SNCETNWFDA LIVAADFLRA
     GTANRSFKHL HIFLISTLEM SAEASESEIR SLLDSLEVML CRVHIISDQI VHSKPITSST
     IFTASSSGAF VDQGVKSEDR IKNENLLNDI LQTEGIFTLT NIDVAHRCLG FYVPKPVRPT
     PWNSTLTIGT KLKFAISAYL LISEQKGLGP FKVTSAGGSA ANSVVTMRTQ HFQNEKPIDL
     EMEDVIVGYM YGSTVVPYDN AIDMDYKSGE AGLTCLGFTA SSNILDEYLS GKGTYLVMAK
     KGCSGSEEKL TALVKAMMAL NVVMVAAKIY RKDTKPRLQT LLPTMHEKRY PCLVMLELLF
     QDEINLVRFP SFLTSKHQPS PEQYAAIDKL IDSMNLMDAV ENENDGAAHE AFGLKETHNP
     NHQFLYRSVV HRAMHPNASL PVLGSDVSEL VSVPKKLIHR AQTAIDEIKL VFPLEEQKRT
     TRAEWLQRVA AMHQGAGDGA SSSAAPATSI DAIDDESERR VVLAVGTMTP AEDFDLLLRR
     GEKFVTVANQ MQTVIFELLF TAMHTPLEKI IMALMMYRGE AQKLGPFRYN EWIRELKRVL
     LERRKHEFWE QVIVQEKLGL IDISESDMST VSVDDAIEFY RIPAATKGSA ETVVKDDVDL
     DSLFEELNG
//