ID   A0A182FLU3_ANOAL        Unreviewed;      1094 AA.
AC   A0A182FLU3;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=Peptidase S1 domain-containing protein {ECO:0000259|PROSITE:PS50240};
OS   Anopheles albimanus (New world malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7167 {ECO:0000313|EnsemblMetazoa:AALB007502-PA, ECO:0000313|Proteomes:UP000069272};
RN   [1] {ECO:0000313|EnsemblMetazoa:AALB007502-PA}
RP   IDENTIFICATION.
RC   STRAIN=STECLA/ALBI9_A {ECO:0000313|EnsemblMetazoa:AALB007502-PA};
RG   EnsemblMetazoa;
RL   Submitted (AUG-2022) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the RED family. {ECO:0000256|ARBA:ARBA00006660}.
CC   -!- SIMILARITY: Belongs to the peptidase S1 family. CLIP subfamily.
CC       {ECO:0000256|ARBA:ARBA00024195}.
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DR   AlphaFoldDB; A0A182FLU3; -.
DR   STRING; 7167.A0A182FLU3; -.
DR   EnsemblMetazoa; AALB007502-RA; AALB007502-PA; AALB007502.
DR   VEuPathDB; VectorBase:AALB007502; -.
DR   VEuPathDB; VectorBase:AALB20_027820; -.
DR   VEuPathDB; VectorBase:AALB20_031475; -.
DR   VEuPathDB; VectorBase:AALB20_037778; -.
DR   Proteomes; UP000069272; Chromosome 3R.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd00190; Tryp_SPc; 2.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR001314; Peptidase_S1A.
DR   InterPro; IPR039896; Red-like.
DR   InterPro; IPR012492; RED_C.
DR   InterPro; IPR012916; RED_N.
DR   InterPro; IPR001254; Trypsin_dom.
DR   InterPro; IPR018114; TRYPSIN_HIS.
DR   InterPro; IPR033116; TRYPSIN_SER.
DR   PANTHER; PTHR12765:SF5; PROTEIN RED; 1.
DR   PANTHER; PTHR12765; RED PROTEIN IK FACTOR CYTOKINE IK; 1.
DR   Pfam; PF07807; RED_C; 1.
DR   Pfam; PF07808; RED_N; 1.
DR   Pfam; PF00089; Trypsin; 2.
DR   PRINTS; PR00722; CHYMOTRYPSIN.
DR   SMART; SM00020; Tryp_SPc; 2.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 2.
DR   PROSITE; PS50240; TRYPSIN_DOM; 2.
DR   PROSITE; PS00134; TRYPSIN_HIS; 1.
DR   PROSITE; PS00135; TRYPSIN_SER; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          45..279
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000259|PROSITE:PS50240"
FT   DOMAIN          324..554
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000259|PROSITE:PS50240"
SQ   SEQUENCE   1094 AA;  120413 MW;  7E7CFF995C6E3199 CRC64;
     MAPSAAGFIS RCLRQTRDIF PLPRHRLTMA MKMGSSRKPS QLAKIVNGQT AQEGQFPWQV
     SIRAALGRSV TVCGGSLIDA QWVLTAAHCA HDYNVFQIGL GSIHLNMARL TMLAVVKHVH
     PEFDPSKLTN DVALIRLPSG VPYSLEIYPV QLPLSIAADD TFVGRRVIVS GFGRTSDAIQ
     SISTELKYES LRIISNAQCA IVYGSSIIRN TTLCAVGWDR SNQNVCQGDS GGPMVIQQAN
     GWVQIGIVSF VSSRGCSTGD PSGYIRTVNY LDWIARTTAL RSLASVLIQV DPAATMQLSA
     GLVLLIAVVC ATASENGQNR NPRIVNGINA QPTPYNAYVL YLNSANAGFF GGGSLISDRH
     VLTAAQNIQG FSRWEIGLGS TVFGQLIKQV STQAISHPSF NSPNRANDIG IVVLPSPVIF
     SAAIAPIALP PLPTLNRPMP MENEEGMVVG FGFITANDQA PSSFLKAAYQ RVIGDNRCSG
     TYQIQLPNHF CAEDTAQRGN VCNGDLGAGF TILDRRVETL AGIASLITAS CDSLTPTGYT
     RVSVYRQWIR DTTGPKFNRR SRMHSDEPET PATQRLTNDD FRKLLMTPRV PAGAGHTVGS
     IRDAMSSKSS ASAVPQSGSS VSASSSTIKT PSSERNEARR KKKNFYAQLK KQEDNKLAEL
     AEKYRDRARE RRDGANPDYQ NLDSSSTTSA YRAVAPDAKS GLDAAERRRQ QIQESKFLGG
     DMEHTHLVKG LDYALLQKVR SEIVAKEQEQ EEEMEKLVDI EATAALPSSG QRPATVSLLT
     EKDLVTSEEI EFHTVLGSNI FRFLEKQRSR VIERNEMFAP GRMAYHIELE DENVDTDIPT
     TVIRSKAEVP LDVCDTQTLT INDIVINKLA QILSYLRQGG RGKKNKRRDK DKPLFKIPGE
     SGGKEVDESI YGDIGDYRPS RRYEDVATSS KLEGKHNYFG KGDSENTVDH EASISAIPPP
     PKLSTQLITK LTAEPEGYAE CYPGLQEMND AIDDSDDEVD YTKMDLGNKK GPIGRWDFDT
     QEEYSEYMSS KEALPKAAFQ YGVKMQDGRK TRKHKTEKNE KAELDREWQQ IQNIIQKRKA
     KTGNDDAEIK KSKY
//