ID A0A182FP26_ANOAL Unreviewed; 118 AA.
AC A0A182FP26;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Mitochondrial pyruvate carrier {ECO:0000256|RuleBase:RU363100};
OS Anopheles albimanus (New world malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7167 {ECO:0000313|EnsemblMetazoa:AALB008289-PA, ECO:0000313|Proteomes:UP000069272};
RN [1] {ECO:0000313|EnsemblMetazoa:AALB008289-PA}
RP IDENTIFICATION.
RC STRAIN=STECLA/ALBI9_A {ECO:0000313|EnsemblMetazoa:AALB008289-PA};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- FUNCTION: Mediates the uptake of pyruvate into mitochondria.
CC {ECO:0000256|RuleBase:RU363100}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448,
CC ECO:0000256|RuleBase:RU363100}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004448, ECO:0000256|RuleBase:RU363100}.
CC -!- SIMILARITY: Belongs to the mitochondrial pyruvate carrier (MPC) (TC
CC 2.A.105) family. {ECO:0000256|ARBA:ARBA00006416,
CC ECO:0000256|RuleBase:RU363100}.
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DR AlphaFoldDB; A0A182FP26; -.
DR STRING; 7167.A0A182FP26; -.
DR EnsemblMetazoa; AALB008289-RA; AALB008289-PA; AALB008289.
DR VEuPathDB; VectorBase:AALB008289; -.
DR VEuPathDB; VectorBase:AALB20_034281; -.
DR OrthoDB; 3375631at2759; -.
DR Proteomes; UP000069272; Chromosome 2R.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006850; P:mitochondrial pyruvate transmembrane transport; IEA:InterPro.
DR InterPro; IPR005336; MPC.
DR PANTHER; PTHR14154:SF3; MITOCHONDRIAL PYRUVATE CARRIER; 1.
DR PANTHER; PTHR14154; UPF0041 BRAIN PROTEIN 44-RELATED; 1.
DR Pfam; PF03650; MPC; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363100};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW ECO:0000256|RuleBase:RU363100};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792,
KW ECO:0000256|RuleBase:RU363100};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363100};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363100};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363100}.
FT TRANSMEM 20..43
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363100"
FT TRANSMEM 49..70
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363100"
SQ SEQUENCE 118 AA; 13406 MW; BF720BEC34C91734 CRC64;
MAAMGRKLMN NLKSKEFREY LMSTHFWGPV ANWGIPIAAL GDLQKNPKII SGTMTTALCL
YSLIFMRFAW KVQPRNMLLF ACHVTNFTAQ SVQGARFIEY HHLGGKARLE KEQSQQAA
//
