ID A0A182G4M6_AEDAL Unreviewed; 938 AA.
AC A0A182G4M6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0000259|PROSITE:PS51456};
GN ORFNames=RP20_CCG002831 {ECO:0000313|EMBL:KXJ78953.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EnsemblMetazoa:AALF002831-PA.1, ECO:0000313|Proteomes:UP000069940};
RN [1] {ECO:0000313|EMBL:KXJ78953.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ78953.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ78953.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ78953.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ78953.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ78953.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:AALF002831-PA.1}
RP IDENTIFICATION.
RC STRAIN=Foshan {ECO:0000313|EnsemblMetazoa:AALF002831-PA.1};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; JXUM01042619; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; JXUM01042620; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; JXUM01042621; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; JXUM01042622; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; JXUM01042623; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KQ561331; KXJ78953.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182G4M6; -.
DR STRING; 7160.A0A182G4M6; -.
DR EnsemblMetazoa; AALF002831-RA; AALF002831-PA; AALF002831.
DR VEuPathDB; VectorBase:AALC636_028231; -.
DR VEuPathDB; VectorBase:AALF002831; -.
DR VEuPathDB; VectorBase:AALFPA_074724; -.
DR Proteomes; UP000069940; Unplaced.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0071944; C:cell periphery; IEA:UniProt.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR CDD; cd21759; CBD_MYO6-like; 1.
DR CDD; cd01382; MYSc_Myo6; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 6.10.220.10; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 2.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR049016; MYO6_lever.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR036114; MYSc_Myo6.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF745; UNCONVENTIONAL MYOSIN-VI; 1.
DR Pfam; PF21521; MYO6_lever; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 1.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989}.
FT DOMAIN 56..746
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 626..648
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 916..938
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 825..852
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 938 AA; 107408 MW; 3CAB1745DE10BD31 CRC64;
MWDSQLVWAR DSQAGYIQGR ISEIGAHEYE VQPVDSKQPK RNCILEDIFP SCEAVSDHDD
NCELMFLNEA TLLDNIKNRY YKDKIYTYVA NILIAVNPYK EIRDLYSKNT IKRYNGRSLG
ELPPHVYAIA DKAIPLYAQD TKYLLKYLCD VAATAGPIEQ KILDANPILE AFGNAKTTRN
NNSSRFGKFI EVHYDSKCQV VGGYISHYLL EKSRICTQSP EERNYHVFYL LCAGAPQQLR
DKLKIGKPDD YRYLSGCTQY FSTANTDRKI PNSQKSRDHM TKGSLKDPIL DDYNDFQDLD
QALTRLGLSE TQKFEIYGLV AAVLHLGNIH FEDNPEDAKG GCRVSQNSEK ALAITANLIG
LDSFELRQAL VSRVMQSKGG GIKGTVIMVP LKIYEANNAR DALAKALYSR LFDHIVSLIN
QNIPFQASSY YIGVLDIAGF EYFTVNSFEQ FCINYCNEKL QKFFNDNILA AEQELYKREG
LNVPEIKFTD NQDIIELIES KANGIFNILD EESKLPKPSY AHFTSEVHSA WQGHFRLSLP
RASRLKAHRV LRDDEGFLVR HFAGAVCYNT NQFIEKNNDA LHASLEGLVQ ESENFLLKRL
FVNGKAPSTK GKLAFISVGS KFKTQLGELM DKLEKNGTNF IRCIKPNSRM VDHEFEGGLA
LAQLKCSGTT SVLELMEYGY PSRVPFNELY NMYKSYLPPE LAKLNPRTFC EAMLHSLKLN
NNDFKFGITK VFFRPGKFVE FDRIMKSDPE NLRAIIANVK KWLVRSRWIK SVFCAICVIK
LKNRIIYRNK CVLVMQKTVR GYLARKQHQP RIKGIIKINA IKSNLSKMHE IANQLKSERE
NMLKQVTDVQ RTIEAAVTRI KGDPKISAAQ IDGLYGEIMN KLDNQMKTIH LKLQEQRNAE
EQERLRKIQA ALEAERKAKE EEERRLREEE ENRKKSVV
//
