ID A0A182G586_AEDAL Unreviewed; 2514 AA.
AC A0A182G586;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=C2H2-type domain-containing protein {ECO:0000259|PROSITE:PS50157};
GN ORFNames=RP20_CCG003213 {ECO:0000313|EMBL:KXJ78897.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EnsemblMetazoa:AALF003213-PA.1, ECO:0000313|Proteomes:UP000069940};
RN [1] {ECO:0000313|EMBL:KXJ78897.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ78897.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ78897.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ78897.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ78897.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ78897.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:AALF003213-PA.1}
RP IDENTIFICATION.
RC STRAIN=Foshan {ECO:0000313|EnsemblMetazoa:AALF003213-PA.1};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; JXUM01042931; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; JXUM01042932; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KQ561343; KXJ78897.1; -; Genomic_DNA.
DR STRING; 7160.A0A182G586; -.
DR EnsemblMetazoa; AALF003213-RA; AALF003213-PA; AALF003213.
DR VEuPathDB; VectorBase:AALC636_008647; -.
DR VEuPathDB; VectorBase:AALF003213; -.
DR VEuPathDB; VectorBase:AALFPA_046514; -.
DR Proteomes; UP000069940; Unplaced.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR45944; SCHNURRI, ISOFORM F; 1.
DR PANTHER; PTHR45944:SF2; SCHNURRI, ISOFORM F; 1.
DR Pfam; PF00096; zf-C2H2; 1.
DR Pfam; PF12874; zf-met; 2.
DR SMART; SM00355; ZnF_C2H2; 8.
DR SMART; SM00451; ZnF_U1; 3.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 4.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 7.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 7.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 404..431
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 432..461
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1616..1643
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1644..1668
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 2243..2270
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 2271..2300
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 2316..2345
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 90..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 314..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 458..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 556..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 672..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 779..852
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 965..1005
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1042..1066
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1161..1190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1378..1431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1554..1596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1683..1737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1754..1827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1858..1878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2120..2139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2155..2175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2392..2514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 672..686
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 787..848
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 980..1005
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1380..1394
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1414..1430
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1573..1596
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1694..1713
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1754..1776
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2453..2467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2514 AA; 273286 MW; 48A01B176CBFED1D CRC64;
DPGGGLPPAM EKSNSCSAGK TTSVSQQHPN LAAAENSGLH HHHHHQNHQP HHQQHQQHTS
APQSTAVASS ASSSDLKYLH KKFKRIASAS LSTVDDSGSD SSKNHVTSAE ALSRSTPFTT
TSTTPTPTAI ASAISDSGPV VAYSTAAAYL PNPTTTTAAT AAVVVANSVV EPPVQQQPCA
NSTIKVKKES DFVVYPYEAS AAVRFHPTVE QHSRTVIDGD DSYQSRLQLT FPCGTPDRLH
QKRPLQQSNG ASLNCVNHVS GASINSFIIS NNHIPVKLEV SGDGTIKPYY PSVNNNSAIN
TSCDLNEKNQ CSTTTGGDVD GAASGRSSNS SGSALSAHEL ATQAEQKYIV VLQQQQQQQQ
SQHQSPLYDP SCTNSVSSTS VEAVGSPAVV TGSSNSGAGI PGKYMCPYCR LNCNKPSVLE
KHIRRHTNER PFRCDPCGMA FKTKSNLYKH CRSRAHRSKF PDKDIGPTVD EDGSLGSDIE
DKELSNSGSD IINRGSPMMD DRVHSPQLLV EKPYKPKFHN AALYAKFDGN KLGPVGGKPV
VSTAMAINNS SGQQQHYISS TAGSGANYSS SNSTSMNGQN VESLEQHISK LISDNEAIVE
VVELPLQKKY HKITGITRGI SVNSSTSSGL AGSDSPSSKL ANALLQKRNS EELQQQQLLM
LQQQHQMQQQ QLQQMQQQQQ QHIQPYPPSE PTRPKTMVAQ IPYVQNHHPP VGTIEVMHQL
PPQQQQQQQQ PQPQMVVRPI SANELQPQQV QYQQPLNLSK PVPNDPPSGA VCEPVAVLAE
PSRIRPPSES SRYSREQSPA SSSSVQHQAP PSTSAVYSQQ QQQQQQVAIP PSQPAPSAAS
QPVPVNDHPQ NPERSIIKDL LLNSREFGVV QNPENENIEK LFTCKSCNTS FRDAEILKYH
TVCFCKGNSS SLNSPDSAPM SPVGSPLSHY MRSKRFNPNS LKSLARGLLL PPSRNPAPLS
KLAKSQLKLP RARPENISLP PKEGSSSRSS SSTSVSASES SAVPEVQTTL PAVAKVVDVV
QNPLPSPGPL LGNTRLVDFQ TSKASNEDTP PRKRQISPQD VGLRRPQHPS LQLFGGDLEV
IERQDQIIPH RYSSGGTVTQ YSPDADSEMS DSASMRARSS MHSGGTVVQL PKANRGGSPI
PMNPTTPKLV VTITPTLTPS LTTPNFFPNA SQQHQTPSER PDSNPISSST VQQPISHFQF
PPINSITAYN PLTLPQVSPG QASQIMHGGK MIPYVQGIPG PNSMLPSNEA QLKGRPRLAP
SPISIKTPLN PIVPGGYMGF DPDDVVRNKK PVLVVPPVKN GMFKEIWSPA KQEINATPKK
SFNFTRIADN ISPRKKETIE PAKKEEIRYF NFENLISKSE IIIKPNTPTE SIKPEPVETK
ALDVPPPPPV VQKPKFLRPN SLPLKPGTFT PKRHHGITPT NNTMPLISPE TPRPSKSCRE
LYFNGHAYTN IGLKSSTKPF YCTVNKTQPF YVQTQKHGQL SMYSNWQVHP ENDPHPLGFK
PIQVMAMYNS SQQGHHSYSI ATKPLTLLVV NSSSANQPIS SAFEVKTSFP HSHYPIPQGA
SPAPKSSGFY PYLPEKSATS NDSIPPRSDS TERTLSGGFE STEEYTYVRG RGRGKYVCKE
CGIRCKKPSM LKKHIRTHTD VRPYSCQHCS FHFKTKGNLT KHMKSKSHFK KCTELGLNPI
PISVDDDGGD IDIENDQQSI SSEQTSTIPF DSDSDPDSDG EDSDDSADYS EPKGGRLPEH
EAAHCLLSLS MTPPTASQVT KSYPSPVSSF GTGNQVPYER SRHPYAPTVS PGLSMSPQQS
PMQSLPPQPQ PAQKHLPMQS QPEPASQPHR RIITFGNTPK VEFNLLKHEQ YYSDPSINKK
KREYNPSYEE DDGAMPIDLT KKPKESFATD PAQSYRMYQQ YPGQTVPKQP LADCPLSNLR
SQVIVRVSDV VTPITGAANL LTTLVSNTDK IPLPLISNGS KELADDNVYF QEYIKQRALQ
DSKMKLSQMK SINNNQYDAE EVRPPVEVVV PVEQPSLVIA KPVPLKATPD KPYRIFNGKN
DMLPKAVVEP TNRIEILPIV NEPIQEAKET VRVDNAETCV ESVNTSRMET LAEVAAGSVK
LPDAGGIDPV RSRSNSLIAG DAASAQPTAS TSGAASSKES AKSVASEYLK LTKSVTMRKR
EDSESGTASD QETIAENSII QPPIVAPIVP PVVVVPPAAN PAPGEIAGIV ARTVVVGEDG
FRTSQAASEF PSLSPYQEDG GRPVCEVCHK KFHKISQLKI HMNIHYMERK FRCEPCGTSF
RSQGLFQKHE RSATHRNKVS MTTTFGIATD SNPRPFYCKD CDVGFRIHGH LAKHLRSKMH
VLKLECLGKL PFGTYTEIER SGTNLTEIDT TDCENSLSSL KRLAVRLNVK DPANVLPGGA
GSDAGPSGNE TDSCDDNQYE NDNESAGEGD SPNGPNHRGT EEEDEGDEGE TSGGDHQQGN
NNFLKRSRMD SEGGGAMNSD GDGDIKRARF QGPPVEQQHG GLMASAGSTG VGDT
//
