ID   A0A182G5B8_AEDAL        Unreviewed;       246 AA.
AC   A0A182G5B8;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE            EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
OS   Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7160 {ECO:0000313|EnsemblMetazoa:AALF003298-PA.1, ECO:0000313|Proteomes:UP000069940};
RN   [1] {ECO:0000313|EnsemblMetazoa:AALF003298-PA.1}
RP   IDENTIFICATION.
RC   STRAIN=Foshan {ECO:0000313|EnsemblMetazoa:AALF003298-PA.1};
RG   EnsemblMetazoa;
RL   Submitted (AUG-2022) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC         EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
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DR   EMBL; JXUM01043197; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; JXUM01043198; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; JXUM01043199; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A182G5B8; -.
DR   EnsemblMetazoa; AALF003298-RA; AALF003298-PA; AALF003298.
DR   VEuPathDB; VectorBase:AALC636_012330; -.
DR   VEuPathDB; VectorBase:AALF003298; -.
DR   VEuPathDB; VectorBase:AALFPA_053525; -.
DR   Proteomes; UP000069940; Unplaced.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR   GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR045103; RNF5/RNF185-like.
DR   InterPro; IPR018957; Znf_C3HC4_RING-type.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR12313; E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED; 1.
DR   PANTHER; PTHR12313:SF0; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR   Pfam; PF00097; zf-C3HC4; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
SQ   SEQUENCE   246 AA;  26628 MW;  53EC4F4BF2CF1EBE CRC64;
     MASTVESAPP QPSAPSLEDL NSASTSQQST TGPNPFSKVT SPSTDADPTA KPISTDQQDS
     AESATSSSGT STGKSKINLE DAAEDGEEKK DDSVFECNIC LDTAKDAVVS MCGHLFCWPC
     IHQWMNGYRN TCPVCKSSIS KEKVIPLYGR GGSKEDPRKT VPPRPAGQRT EPEQPQGFQG
     FTGDGGFHMS FGIGAFPFGF FTSTLNFGEF RGNPPHENTR EYEEDQFLSQ IFLYVALIFM
     AWLVLA
//