ID A0A182GAF3_AEDAL Unreviewed; 875 AA.
AC A0A182GAF3;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=C2H2-type domain-containing protein {ECO:0000259|PROSITE:PS50157};
GN ORFNames=RP20_CCG006333 {ECO:0000313|EMBL:KXJ77869.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EnsemblMetazoa:AALF006333-PA.1, ECO:0000313|Proteomes:UP000069940};
RN [1] {ECO:0000313|EMBL:KXJ77869.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ77869.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ77869.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ77869.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ77869.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ77869.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:AALF006333-PA.1}
RP IDENTIFICATION.
RC STRAIN=Foshan {ECO:0000313|EnsemblMetazoa:AALF006333-PA.1};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JXUM01050899; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KQ561666; KXJ77869.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182GAF3; -.
DR EnsemblMetazoa; AALF006333-RA; AALF006333-PA; AALF006333.
DR VEuPathDB; VectorBase:AALC636_007542; -.
DR VEuPathDB; VectorBase:AALC636_012380; -.
DR VEuPathDB; VectorBase:AALC636_018201; -.
DR VEuPathDB; VectorBase:AALF006333; -.
DR VEuPathDB; VectorBase:AALFPA_056624; -.
DR VEuPathDB; VectorBase:AALFPA_073357; -.
DR Proteomes; UP000069940; Unplaced.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.1800.20; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24379:SF67; IP01257P-RELATED; 1.
DR PANTHER; PTHR24379; KRAB AND ZINC FINGER DOMAIN-CONTAINING; 1.
DR Pfam; PF00096; zf-C2H2; 5.
DR Pfam; PF13894; zf-C2H2_4; 1.
DR SMART; SM00355; ZnF_C2H2; 13.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 4.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 9.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 8.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..875
FT /note="C2H2-type domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5038214356"
FT DOMAIN 395..422
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 423..450
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 452..480
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 544..571
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 571..593
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 643..671
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 671..693
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 808..837
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 79..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 271..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 597..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..143
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..235
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..301
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 875 AA; 100293 MW; 936FC8FABC63A930 CRC64;
MHFNLVTLSL CSSGCFGGSG DFLLVRDFNV KINQNDSISQ SICAECKIRL NEFREYRLQC
LDVQNVLWNE RAVINDVQNS PEESALENQR NDKAMPLPNS EAEEKTNNVI TEETDQEVIL
VEDLSSSSEC QEEDTRESNM SVDEYYPDDD DQVEGAPTAL SSIEILELSD DEGPKTKKLP
SQKARRKETA KHTCEMCGKK VRGDQMEGHT NKHLERAVIN DEQISSEDSA LEDQRNDDAV
SLQTPRAMEE VYYAGPEELD QEVILLEDLS STSECQDEDT RESNMSVGEH YPDDDDDQAK
DSATALSSIE ILESSDDEDL KTKKLQTPNS RKTKIKKYTC EMCGTKLQGS RMEGHMNKHL
GMKPYKCERG CTDAAFTDNY HRIWHYRHRH DAHKYCCPVC NRSFATRQGL YSHKRIHHAT
KSFKCDICQK EFATEYLQKK HMLGHGAKED KFSCSKCNAS FPTEYALQRH VPQKHFSSEG
DDFGRNWLQA QLEQAEVKCE DELMLHDARQ DEFVAAEEIR IRSDSDAQKI LPGNLSNENQ
PIKLECDVCG KVFSVKRQLV LHKRTHGLRK YKCSICSGSF LQPSRLARHM LIHDKTGNIK
TDQGKPANDQ PEDVPKQNLQ NHSEVKAGSE NVDQQDDQSD LTIECAMCDK KFRVKKQLSD
HRRQVHGPRD HKCTFCGKAF RSRSRLAEHA TIHKSFVSNE TGNVDISVES EGTATDVKYD
PKKRQYIYEK EPCSLCKRMI KVIFMEGIQP YKCEMGCTEE KFHCKFQRKT HYNDVHGWNA
YECHICHQYF SSNRSCMIHK AKAHAHGHEC QECFTVFATS SGLKKHIAKT RHIKTRKDTQ
PIVLVELPEL EQMEKEEDLF EAEDIKVELQ SDEEG
//
