ID A0A182GAT7_AEDAL Unreviewed; 552 AA.
AC A0A182GAT7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=C2h2-type zn-finger protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=RP20_CCG006554 {ECO:0000313|EMBL:KXJ83434.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EnsemblMetazoa:AALF006554-PA.1, ECO:0000313|Proteomes:UP000069940};
RN [1] {ECO:0000313|EMBL:KXJ83434.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ83434.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ83434.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ83434.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ83434.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ83434.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:AALF006554-PA.1}
RP IDENTIFICATION.
RC STRAIN=Foshan {ECO:0000313|EnsemblMetazoa:AALF006554-PA.1};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
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DR EMBL; JXUM01008753; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KQ560268; KXJ83434.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182GAT7; -.
DR EnsemblMetazoa; AALF006554-RA; AALF006554-PA; AALF006554.
DR VEuPathDB; VectorBase:AALC636_025553; -.
DR VEuPathDB; VectorBase:AALF006554; -.
DR VEuPathDB; VectorBase:AALFPA_078128; -.
DR Proteomes; UP000069940; Unplaced.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1800.20; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 4.
DR InterPro; IPR012934; Znf_AD.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24376:SF216; FI03704P-RELATED; 1.
DR PANTHER; PTHR24376; ZINC FINGER PROTEIN; 1.
DR Pfam; PF07776; zf-AD; 1.
DR Pfam; PF00096; zf-C2H2; 4.
DR SMART; SM00868; zf-AD; 1.
DR SMART; SM00355; ZnF_C2H2; 10.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 4.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS51915; ZAD; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 7.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 6.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU01263}; Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU01263};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 8..84
FT /note="ZAD"
FT /evidence="ECO:0000259|PROSITE:PS51915"
FT DOMAIN 279..307
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 311..338
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 337..365
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 366..394
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 467..494
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 495..523
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 114..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..203
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 10
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 13
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 57
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 60
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
SQ SEQUENCE 552 AA; 64165 MW; 57F04CF0B16A8957 CRC64;
MEDIDVEKIC RLCCAKKGRL RSLFEGPQKY ARTLPDIICD ISRLQVERND GLPQMVCRVC
STALVKMYDT IESYRNNDLR LRQMLSMVPP VEIKEEEVDV DLLENAFVQE LQIEHVPMKE
EDMDEEYLES DLPSRDTSQI TEQLEGEVLF KREDSDDDSE DVPQKDDEEW EPQDIPDKDD
KKPLVGKSRK RKKQKDETIK TAGRRHRKAK CPDRPRKNDF KCYICMSDSH GTPEALLAHL
NGTHQDLLPF TCPECVMETI VINTLLALNS HKKQHLNPEK CPLCDKRYTH KNNLEMHIQM
HHSADNSDNP LTCTHCGEMY PTKSALYHHT KIHTTAASCE ICGKIFKERS KLKRHIQNKH
EKLRKYECHI CQKKLSSMDS VQIHIKTFHS AKTLKCSFCP KTFGSELVHR AHEKRHLDHP
DLEPKNDWKE YYTIVDKATK QRKCNLCGMV TTAIGSHLAR VHFPTEYRCK ICDQAFKSKQ
TCEVHELAHE YGKAFHCPIC AREFSERKLL ICHLRTKQHQ DHPLALEMLG TVRTKREEKN
DGDVDVDDAQ SQ
//
