ID A0A182GEH3_AEDAL Unreviewed; 120 AA.
AC A0A182GEH3;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Wntless-like transmembrane domain-containing protein {ECO:0000259|Pfam:PF06664};
GN ORFNames=RP20_CCG008514 {ECO:0000313|EMBL:KXJ76990.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EnsemblMetazoa:AALF008514-PA.1, ECO:0000313|Proteomes:UP000069940};
RN [1] {ECO:0000313|EMBL:KXJ76990.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ76990.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ76990.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ76990.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ76990.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ76990.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:AALF008514-PA.1}
RP IDENTIFICATION.
RC STRAIN=Foshan {ECO:0000313|EnsemblMetazoa:AALF008514-PA.1};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JXUM01058006; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KQ561982; KXJ76990.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182GEH3; -.
DR EnsemblMetazoa; AALF008514-RA; AALF008514-PA; AALF008514.
DR VEuPathDB; VectorBase:AALC636_013964; -.
DR VEuPathDB; VectorBase:AALF008514; -.
DR VEuPathDB; VectorBase:AALFPA_058629; -.
DR Proteomes; UP000069940; Unplaced.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015643; F:toxic substance binding; IEA:InterPro.
DR InterPro; IPR040416; TMEM181.
DR InterPro; IPR047843; WLS-like_TM.
DR PANTHER; PTHR31918; TRANSMEMBRANE PROTEIN 181; 1.
DR PANTHER; PTHR31918:SF1; TRANSMEMBRANE PROTEIN 181; 1.
DR Pfam; PF06664; MIG-14_Wnt-bd; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..120
FT /note="Wntless-like transmembrane domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5038214412"
FT TRANSMEM 45..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..69
FT /note="Wntless-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF06664"
FT REGION 95..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..120
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 120 AA; 13655 MW; FD5F66428034B57F CRC64;
MRLKFLTLLM LFVLAISLTV TMCRFGFGIL EDNFVAKLNT TYKSSAQFMC FYGLLNFYLY
TMAYVYSPNG RPLHEATITK DNPAFSMIND SDEEVVYGSD EESRRPLNAA HGKGNDYDSD
//
