ID A0A182GHE5_AEDAL Unreviewed; 635 AA.
AC A0A182GHE5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Ionotropic glutamate receptor C-terminal domain-containing protein {ECO:0000259|Pfam:PF00060};
GN ORFNames=RP20_CCG009942 {ECO:0000313|EMBL:KXJ76294.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EnsemblMetazoa:AALF009942-PA.1, ECO:0000313|Proteomes:UP000069940};
RN [1] {ECO:0000313|EMBL:KXJ76294.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ76294.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ76294.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ76294.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ76294.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ76294.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:AALF009942-PA.1}
RP IDENTIFICATION.
RC STRAIN=Foshan {ECO:0000313|EnsemblMetazoa:AALF009942-PA.1};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
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DR EMBL; JXUM01063522; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KQ562255; KXJ76294.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182GHE5; -.
DR STRING; 7160.A0A182GHE5; -.
DR EnsemblMetazoa; AALF009942-RA; AALF009942-PA; AALF009942.
DR VEuPathDB; VectorBase:AALC636_028809; -.
DR VEuPathDB; VectorBase:AALF009942; -.
DR VEuPathDB; VectorBase:AALFPA_056498; -.
DR Proteomes; UP000069940; Unplaced.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050906; P:detection of stimulus involved in sensory perception; IEA:UniProt.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR PANTHER; PTHR42643; IONOTROPIC RECEPTOR 20A-RELATED; 1.
DR PANTHER; PTHR42643:SF35; IONOTROPIC RECEPTOR 41A-RELATED; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 323..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 580..602
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 321..590
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00060"
SQ SEQUENCE 635 AA; 71715 MW; EA19D0FEA4F390B5 CRC64;
MDLLAINSST ASLMSVVNII ALNYFTEFHT VCVIKTSLDY VLINVPIPTA VITVDSTFNE
TFQTAVDEGC QAFIVSERAL MTFMDAFVEI HDNSDQRSSN KRLLVLLDMY DLEFVNAFIK
HPNTLELPST ALLVPNYSED AVDLYSTKFF NDGTRSTVVV EIEPIVGLDC YPDKFSNMNG
VPIHLCTLMY PPYAYYEETI PEKANARYHT SFKKEDIPLY LDGTEVILLV EFCRKYNCSV
EASFDEVFLW GEVYDNHTGN GLLGSVVERR ADIAVAAIYY WRQPYKFATY TQPISRSGIT
VLVPKPRILP PWRTPFLSFS SSLWLAVFVA LCVGVLAVWL IEKIRFKILQ PKELPVTISD
ALLTMIGFYM EQSARMRTDM ISCVLLFTSL LFAGFMVGNT YGGGLAGIMT IPQYEKPIDT
TMDLAETGIM WGATALSWIF SIMSAPQPYM KKLVKSYRVI SDDFMAKHSK THDMGFAGER
TEFQHFVPAD FVDSEASTML QLLKDDLYWE SVAAIITKTC PFKQKFNDLI MQVKQSGIQN
YWELQASNNY LHGTIQLNIL NARSVGSGDN VVRLTISHFL GAYMILGAGL GMATLTFLLE
IFRVRLTQSI HRKARQLKLK LYNLSKSIVN EAFSE
//
