ID A0A182GMR8_AEDAL Unreviewed; 4219 AA.
AC A0A182GMR8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KXJ74972.1};
GN ORFNames=RP20_CCG012617 {ECO:0000313|EMBL:KXJ74972.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EMBL:KXJ74972.1};
RN [1] {ECO:0000313|EMBL:KXJ74972.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ74972.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ74972.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ74972.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ74972.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ74972.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the VPS13 family.
CC {ECO:0000256|ARBA:ARBA00006545}.
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DR EMBL; KQ562865; KXJ74972.1; -; Genomic_DNA.
DR STRING; 7160.A0A182GMR8; -.
DR VEuPathDB; VectorBase:AALC636_000630; -.
DR VEuPathDB; VectorBase:AALF012617; -.
DR VEuPathDB; VectorBase:AALFPA_056250; -.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd14306; UBA_VP13D; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR041969; VP13D_UBA.
DR InterPro; IPR026847; VPS13.
DR InterPro; IPR026854; VPS13-like_N.
DR InterPro; IPR031645; VPS13_DH-like.
DR InterPro; IPR031646; VPS13_extend_chorein.
DR InterPro; IPR031642; VPS13_mid_RBG.
DR InterPro; IPR009543; VPS13_VAB.
DR PANTHER; PTHR16166:SF141; INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13D; 1.
DR PANTHER; PTHR16166; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13; 1.
DR Pfam; PF12624; Chorein_N; 1.
DR Pfam; PF16909; VPS13_DH-like; 1.
DR Pfam; PF16908; VPS13_ext_chorein; 1.
DR Pfam; PF16910; VPS13_mid_rpt; 2.
DR Pfam; PF06650; VPS13_VAB; 1.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50030; UBA; 1.
PE 3: Inferred from homology;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ SEQUENCE 4219 AA; 474818 MW; 0980DF6951EE51EF CRC64;
MLRELIAWVL NNYLGKYVEN LNTAQLTIAL LSGQVELENL PLRKDALRYL GLPLQIIGGT
IGKVKLTVPV RQFRTASWCL NIDNVNVVCG PIDLNEWNPE IEQQTELDFK IASLDRLEAK
WRAQRETPVT EGTYYASSYS GWLSYGTSLV TNIIENLQLK VNGIHIRYED GLTIPNQRFA
CGINIEALSA QSCDSNWVPG QTSNWSQQQV TFKLVELTNF AFYWDPVGGN EQVYIINPIS
AKAQLKRDRS ETPLRTRSRP RLVCDLVWDE IKITLSDIQY NQMMQCARGL DDIARYRRFK
LHRPNSTVRE DPKAWWRYAV RCHGLLRHAQ SDPFVIAREN LRYISVYGRV VANPNEVLSS
DNKSFKDRIE RERDFDELKL LRDVCMARMP SLDKSPQMNQ GKNMLVHFFP QWWGWYNNNN
GNAAESPPTP EQNDAPLEAN WGPEEDLSPV SSFEDEILNA LSDSVDTNSL LKRDAVFGRF
NFVLRQGTMD FCSALEMTPK LQFQFQNLKL DVETRPRSGS HYLSLSLGSI FIKDRITPNS
QFPDLVKPQA KEDLQVSAKV CPVKSRSQSL QQSPMEPIFE VQYERKPLSH DTDYRLLVKS
QSLDIVYNMD AVKWLVEFLT KPHQQYDTRR KLENMKNKTK MELMRNMKNI LEGHLNTRKT
WTLEFDIFAP QIIFVDNFAD RQNSTIVVVD FGRLQLTNGN KPFPGSALVR KSGNNDSSPE
ITVENDDEDA FMTPCSTPPG SEASSTHSPT LQSAMSELPE LNITNGDALD EHSLYQKLYD
RYHIHLTDLQ VLVCRGKERW NFASTKGTST LHVLDRFSIA LQVERRVVYT SDPQYPSLTL
SGTLPKLNAH INEYKVSTLL TLSNSLTKAG QVWTGDVPDV TEVPPTDLQT PNDEDSSTDT
SSAYRKESAN IIVFQFTIDQ MSLEVQSRGR SIAELQVSGV KAGFSRRPED VTLTLSVHGL
LLADAMQSFG PDFELLIASH RHVGMDSLSG SLRQSEPCSP CSPGSPDPNM EYRRPTSPLT
ISKALSNLQK ETTSPTWNAA PFGDLDALIT VEVTFMNNEK VGENLQMANI QFNNLDIIAN
QETIVELLGF VKRVIPKAPP KPPEQTRPIP KPEDINASTG SIAAAVGVTN SEALDGVVSP
VRTEITFDFH RLNVLVLRAL MRDSYMVGRK VGTFTMSEAK IHASLGSSIT VEGSLGGLQV
LDLTPEGINH QRILSVGKDP LTDPPEIRQG PDLMTSLAQE VYGIPPKSTV DGLQEERQAL
SFGVSKDINA VIDVRVKMAS VWFIHCARFM QELTWCASEF KHYLKNLARS IRDKATDMAL
GLVQSRGDLS SSRPESIYNS PRRARKQRTV SLSKTQEVLL NSEYTLRVDI TLETPVLILP
RSSSSPQVLV AHLGRITVSN TQELPDSPSN ESNINLTTTI INEEISIEER IVYNLSDVDG
VFDTLDDEND SSRIRFAKEN SMEFIDSVVQ NYDLYRIDIK NINLYSLDTT NRKGFRFSAL
PRAEEFYSCK ENAIPIIHDT IFSLEISRDI SEIDSDGFTI SGRVVKPLRV SLKRQQYEQL
LETIDNLFKI PKDLVRPPTE TTVLDKHLEI IEESTFNAYP ITDKVRRGLM YQNSFEERSS
SLNLKVNFEL PAFIIQLNDN RNDPQIQISF IDFSVQFEKR NSYETHVKIS LRSLMMEDLL
QSDTAKTRYM VVSSSQNDNY GRPTSSFASF SCPNLVGLLG NVEELPNSLP TNFDDKTSFY
FLAANKSLCP DTPPPSPSTQ RNNQSTTTGS EEANLVIYTS VMVDPACPAF ATQFNSLQQS
SSIDFNSLDL IVSVESWFVL LNFFGLLSDD ESSGSSQKSS SDQDTREKAP PTGHSKLDIS
VRSLSLVLAK PSYEIAKANV SNAQFTVSKR NSAKQVEGKL GSITLSDLTP YGFIYREKFM
TTGNEALSFV YSRDSAKSNA RNLQKDARLR IEMSSVRFVH TKRFIAEIQL FFKEFSQLQT
PVMRKIKTTD SKAYLKQRPT QLGLEIKAGA PILILPMAFN SEQVIVADLG EFTLKNEFRM
SGDPGVISVS SNPSVKEVLD VMYVNLLHTN IFAARKVVKP EGHLGQVDFD DAAVDMKSFW
LVKQGPSLLK EKCHLKLQVE RNMDSWNSHY VPDISVHGTL SRLEAVLDLQ QYRLVRGFLS
YNLGENLDEL YQRPMSNIPN STLSLNTDTD PIEEVWKNLA IHLELQDVSV RLETLGSDRK
PTPLACINFI KSKLLVDSLS DGAQDIDLVS QEILIKDTRF DRPCTYQGEI RNVFPDILQP
IVSDPGEGQV QAEIHSRRRQ DLTKFTILLN NMRLMAILDW LENAKDFILQ QEDQPQIGLD
INAGERIASS VDAGKRAPTS SEENRMELKL NITDSELVLV EKTDQKDTNA VILKSTTVVS
FRPFELAKTM SINLNNLEVC SCVLGAEDGT ALSIIDPVTV NMDLRQGVLD VQMQKQLCIR
LSYHDVKMFQ RMLESLPGQT KNARDSSKQA SMEDGVESNT AVEKLVLLGF NREDCLEALD
KCRYQIDDAA LWLTQNSEPQ KYESVAQKSG TTVEAIELKA PCISICVIDD CRDADVPLLE
LSLSKLDLRQ ELGQSTMSMD GTDTALEVFS PTTNNFVGFK AGRMVGVFAG DYYNRALSGW
EPLIEPWKVE AQWGYCLGQT GTSRNLLNLR IESNDTLRLN ITSTLIDLYQ MVKENWTQDY
YNSNNVNMAN RSPVNYRRRT PFIPFAIKND TGVRIWYTTV ISTEVSSRSS VLTDPNTQWT
LVDPGGTATF SYATKSKQRH RDTHKFNLHQ IAVRADGWQE VGPISVDRVG TYFRHARADI
VDNYSQIPRA RIVFAVTLEG SAQKLITVRS ALKLTNKLDN PVLVKMEHLF GHLSIRDWPD
TKAQILHSNE VLNIPLTHVH ATLFFRPLPQ NVALIEEVNS EEMSNSSDGW TLLQKFDVHK
SFNSNNGFQF TDKGVKWNEA METGEVYQEL RTCRGLRDRS YRMLVALRKE GYPTRDVLPG
HQITIWPPLR IHNLLPCDLL YQLPSGSHGR ISASETAKII ELDIEESVAL TLRSADVVGF
YGSAEQDVRL FDTKARMLKL RAFINIVKGR GIQISISAPY WLINKTGIPL VFRQDDLDCE
SAGQFSENEQ ARMISPFMFS FSDPSCSGCL TMRLGKRFGP SVSYCQPFKL DQGIKHRQLI
GGSESFIIGI EVQRARGRYN QTSIVTFSPR YQLYNRSSYK LQVLQKCFTT TVYDAIAKSN
SIEAVPGCHI AYHWPRLDKV QELCVRLPEI PECLWSAGIP IRETQSLYIN IRTVNGAMHF
LRLETILQGA TTFMIFSDAQ SLPPPIRLDN YSEVPIVFHQ RALPHVENHL KSYVRPHSSI
AYVLDEPLGY QYLQLEAPGG DYQVCHLDRF DEFRLTYENF IYIAFSQTFV ATPSFEFGST
SYPESQQLVL GVVDSRVVLV RKQAGDRSQL WRMNHEKQLE HEGSTPPSEP GKKQQRFVLD
LDRPPQPTQF INLVVRPANR QRKSTQTWRF TEEGRLMCEH SNMCVQARGG IFGLQAGSEA
VLGMCVSETK ALNRFGVPYD QAIERQKLRP GSGCLSVRHI MDGPIKCIEI KDVKNLAGGP
LALDAAWKHV SHILHERTGR RSFEMLQNKE QNEYNVIVKL KRGIGLSLIS NQPCEELAYA
ALEDIKMQLT STPSEVSLDF SVGDMQIDNQ LFETSCPIMM YTINPSSSND TPNSATARSL
QLDVTLLPSP NTNAVIFKHF LLQVQPVAVY LEERLILRMI KFFGLAKSTT LPAALPDESD
HETQKIIYKV LDANVKRYYF GNLQIIPSQI RLSFITASKL APEFAEIKRN LGFTFIKFED
AVISFEKFTH KCHFETLDAY LNAIKSHYKQ EIKWQAANIL GSVDFLGNPL GFANDLTEGV
SGLLLEGSIS SLVKNVTHGI SNSTAKLTET ISDGLGKVVF DDEHVENRQK ILDVALSGGS
GSTTGDHLVA GFKGFTYGLL GGVTSVVKHT YQGAVNDGFS GFVTGLGKGL VGTVTKPVIG
VLDLASETAN AVREQSKSSS RILPERKRHP RVVTGAPGGL LPPYSSIQSK GQQYLFLINK
RNFSEHFMAY EPCLLDTKDS KMRLLVSAEN VWGFSKNEET TTIVFQYPLS DIISCHPVVV
PPPTSSDSSS RTRRTTYIEF CLTLPSKSLT PSAPEMVKRP RVRCQNEDIA KKICHHINFA
KCIYDEREQT LYSNAVIET
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