ID A0A182GN29_AEDAL Unreviewed; 542 AA.
AC A0A182GN29;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KXJ82611.1};
GN ORFNames=RP20_CCG012773 {ECO:0000313|EMBL:KXJ82611.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EMBL:KXJ82611.1};
RN [1] {ECO:0000313|EMBL:KXJ82611.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ82611.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ82611.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ82611.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ82611.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ82611.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 2 family. Mth
CC subfamily. {ECO:0000256|ARBA:ARBA00008979}.
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DR EMBL; KQ560401; KXJ82611.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182GN29; -.
DR VEuPathDB; VectorBase:AALC636_006161; -.
DR VEuPathDB; VectorBase:AALF012773; -.
DR VEuPathDB; VectorBase:AALFPA_046158; -.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR CDD; cd15039; 7tmB3_Methuselah-like; 1.
DR CDD; cd00251; Mth_Ecto; 1.
DR Gene3D; 2.30.160.11; -; 1.
DR Gene3D; 2.170.180.11; Methuselah ectodomain, domain 2; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR044860; Methusela_ecto_dom_1.
DR InterPro; IPR023311; Methusela_ecto_dom_2.
DR InterPro; IPR010596; Methuselah_N_dom.
DR InterPro; IPR036272; Methuselah_N_sf.
DR PANTHER; PTHR47154; G-PROTEIN COUPLED RECEPTOR MTH-RELATED; 1.
DR PANTHER; PTHR47154:SF2; G-PROTEIN COUPLED RECEPTOR MTH-RELATED; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF06652; Methuselah_N; 1.
DR PRINTS; PR00249; GPCRSECRETIN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR SUPFAM; SSF63877; Methuselah ectodomain; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
SQ SEQUENCE 542 AA; 63241 MW; 552258830DDC7DE6 CRC64;
MKINAKYVCA LLAVFSVKHI SCDSLPCDFI DSINITDGIR DVLGNIVHNN ILYKPKYYRT
IDYDYEDFST KKFVNEYIRG CPCAVRLCVR MCCPEGTVMY DYQCLPTTNK LEVLVNTTLF
NVQRSFEVVD LTENNMYGFL YGKPCESVYE LNRADDIWSF ARNGSIIHDS RLLTRNQFCL
MQNNVSQPVT PFVCFEPQEE FKYALYPIGM LLSVPFLLVT FFVYACIPEL RNMHGKSLMC
YVLGLAAGYT VLSLVQMGLF EGSSLHCKVS GYLVYFWFMV SFFWLNVMSF DIYWTFRGVR
GAKSTERKKF ALYSLYAWGC PLLLITISLI FDHTELIPPN YRPQIGVTRC FIIENKYVEF
FYMYLPLLLL VFANMFFFVI TAVRIIKIQR ETSMVRRGDS KRHSKLDNDR DRFGLYLRLF
IVMGVTWSLE VISWAVNNVA WIFYISDVCN CIQGFLIFML FVWKQKIKRL IYKKYVCNDR
LILSTCFLAP ECCLFFFAHR IARVLPFGLF SAGFCADGVC LTPFFLSTKF WGVRMMSCKW
WG
//
