ID A0A182GP82_AEDAL Unreviewed; 177 AA.
AC A0A182GP82;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=CTCK domain-containing protein {ECO:0000259|SMART:SM00041};
GN ORFNames=RP20_CCG013321 {ECO:0000313|EMBL:KXJ74605.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EnsemblMetazoa:AALF013321-PA.1, ECO:0000313|Proteomes:UP000069940};
RN [1] {ECO:0000313|EMBL:KXJ74605.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ74605.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ74605.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ74605.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ74605.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ74605.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:AALF013321-PA.1}
RP IDENTIFICATION.
RC STRAIN=Foshan {ECO:0000313|EnsemblMetazoa:AALF013321-PA.1};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JXUM01077883; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KQ563032; KXJ74605.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182GP82; -.
DR STRING; 7160.A0A182GP82; -.
DR EnsemblMetazoa; AALF013321-RA; AALF013321-PA; AALF013321.
DR VEuPathDB; VectorBase:AALC636_030793; -.
DR VEuPathDB; VectorBase:AALF013321; -.
DR VEuPathDB; VectorBase:AALFPA_080378; -.
DR Proteomes; UP000069940; Unplaced.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR006207; Cys_knot_C.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR004133; DAN.
DR PANTHER; PTHR15283; GREMLIN 1; 1.
DR PANTHER; PTHR15283:SF5; NEUROBLASTOMA SUPPRESSOR OF TUMORIGENICITY 1; 1.
DR Pfam; PF03045; DAN; 1.
DR SMART; SM00041; CT; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..177
FT /note="CTCK domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5038293858"
FT DOMAIN 43..140
FT /note="CTCK"
FT /evidence="ECO:0000259|SMART:SM00041"
SQ SEQUENCE 177 AA; 19872 MW; 8A3DE7DE3A24B4B0 CRC64;
MSGWPAVWGS ALLLLLIAAA YGNREHKVHN IVLYPDKHSW CSTRNISQVI SYPGCKQVTI
DNNVCVGACF SYSIPHTEPS DPGEVIGPYC DSCQPSETTW HHVTLDCSEN SSNNNDEESK
PAVLVKRVQI IKNCSCTSCE KQTHKKHHNH HHQDYQVTQV RSRLLGYERP FISLSKG
//
