ID A0A182GPV9_AEDAL Unreviewed; 616 AA.
AC A0A182GPV9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KXJ82304.1};
GN ORFNames=RP20_CCG013625 {ECO:0000313|EMBL:KXJ82304.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EMBL:KXJ82304.1};
RN [1] {ECO:0000313|EMBL:KXJ82304.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ82304.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ82304.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ82304.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ82304.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ82304.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
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DR EMBL; KQ560461; KXJ82304.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182GPV9; -.
DR STRING; 7160.A0A182GPV9; -.
DR VEuPathDB; VectorBase:AALC636_038438; -.
DR VEuPathDB; VectorBase:AALF013625; -.
DR VEuPathDB; VectorBase:AALFPA_069216; -.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd03483; MutL_Trans_MLH1; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 2.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR032189; Mlh1_C.
DR InterPro; IPR002099; MutL/Mlh/PMS.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00585; mutl; 1.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF12; DNA MISMATCH REPAIR PROTEIN MLH1; 1.
DR Pfam; PF01119; DNA_mis_repair; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF16413; Mlh1_C; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989}.
SQ SEQUENCE 616 AA; 69472 MW; C7B6FA2AD5B5BB7D CRC64;
MEPGVIRKLD EVVVNRIAAG EIIQRPANAL KEMMENSLDA KSTSIQVVVK AGGLKSLQIQ
DNGTGMICLS FVIDEKCAFK ATYEDGKLKG DIKPCAGNQG TQITVEDLFY NVPMRKQALK
APNEEFQKIS DVVSKYAVHN PQTGFMLKKF GENATIRTQA KSSVENNIAL IYGSSISKSL
LKVTLDDDIL QLQVNGFITN VNFSLKKGMF LLFINHRAVD SANIRKAIDQ IYSLYLPKGM
APFVYLSIEL NPNNVDVNVH PTKHEVHFLH EDEIIEKIKQ VVEAALLGGN ASRTFYTQAL
LPGAPEPAET SKLNESTGDK PKPDYKFVRT SHNDQKLDKF FGINLSRNAS MNESTNNGDE
LGGSLVVPKQ EKLVRETKLT SVLNLRKAVE DLCDRNLRTI ISELTFVGVI DRHRVLIQYD
TKMFLVATRT LFEELCYQML LFNFENLDAM TFTNPLPVRE LAMFALQDAE SGWTEDDGPR
DELAERIEEI LISKAPLMKE YFSLCISADG MLESIPIVVQ EYIPSLAHLP MFVLRLATEV
EWDEEKECFD TFCREVARYY AKIAFTKADA EYKWEVEHSI FPAIKQYLLP PKSFAKNGSL
LKVANLPDLY RVFERC
//
