ID A0A182GQ89_AEDAL Unreviewed; 497 AA.
AC A0A182GQ89;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=PX domain-containing protein {ECO:0000259|PROSITE:PS50195};
GN ORFNames=RP20_CCG013825 {ECO:0000313|EMBL:KXJ74360.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EnsemblMetazoa:AALF013825-PA.1, ECO:0000313|Proteomes:UP000069940};
RN [1] {ECO:0000313|EMBL:KXJ74360.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ74360.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ74360.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ74360.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ74360.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ74360.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:AALF013825-PA.1}
RP IDENTIFICATION.
RC STRAIN=Foshan {ECO:0000313|EnsemblMetazoa:AALF013825-PA.1};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
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DR EMBL; JXUM01080104; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KQ563165; KXJ74360.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182GQ89; -.
DR EnsemblMetazoa; AALF013825-RA; AALF013825-PA; AALF013825.
DR VEuPathDB; VectorBase:AALC636_025717; -.
DR VEuPathDB; VectorBase:AALF013825; -.
DR VEuPathDB; VectorBase:AALFPA_076121; -.
DR Proteomes; UP000069940; Unplaced.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005178; F:integrin binding; IEA:InterPro.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06875; PX_IRAS; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR037904; Nischarin_PX.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR15454:SF35; NISCHARIN; 1.
DR PANTHER; PTHR15454; NISCHARIN RELATED; 1.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00365; LRR_SD22; 3.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS51450; LRR; 3.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..116
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
SQ SEQUENCE 497 AA; 57151 MW; 9AB95D276E7B6A2B CRC64;
MSNYQLHLNE TSISIPRIIT VDSVNYYEVL VKCGHVMWTV NRRYRDFDDL HAKLVQERSV
AKDKLPPKKV IGNKSPTFLK KRQEALEQYL KEMLTFLKVT MPREFVEFLE FHRYDIIFLS
QNLANCFFLR GESFLAKSKK YGFSVLELHA FSERLKIPCP STEAADGALN FSHIMDFCSQ
LETVIVLPTK NSLPMILYDD DSDKYIPHAL HKPIGSSNII PSQLRYDLSV FRGLKNLIIY
GISTENIENV GGLRESLLRI EIYKSEIKHI RQITLCDDIH RNSTEELDRS KVWKNLRHAV
FKENQLMEID HSIRLFPNLK DLVLDKNRIE SIAHLSHLNN LQALSLRCNR IAECRDWHLQ
LGNLVSLNLS QNKIRLLEGL SKLYSLVNLD LSCNQIDDIN EIDHIGNLPL LENLRLMGNP
VAGSVDYRAR VLSRFGERLQ EIYLDNEKGN QLEYDTALVL SALRISAQNS QRKLHSLLDT
ASAEDKLPGT SGSSCSR
//
