ID A0A182GUH4_AEDAL Unreviewed; 398 AA.
AC A0A182GUH4;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KXJ73379.1};
GN ORFNames=RP20_CCG015987 {ECO:0000313|EMBL:KXJ73379.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EMBL:KXJ73379.1};
RN [1] {ECO:0000313|EMBL:KXJ73379.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ73379.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ73379.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ73379.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ73379.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ73379.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: One HIP oligomer binds the ATPase domains of at least two
CC HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40.
CC Stabilizes the ADP state of HSC70 that has a high affinity for
CC substrate protein. Through its own chaperone activity, it may
CC contribute to the interaction of HSC70 with various target proteins.
CC {ECO:0000256|ARBA:ARBA00037033}.
CC -!- SIMILARITY: Belongs to the FAM10 family.
CC {ECO:0000256|ARBA:ARBA00009015}.
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DR EMBL; KQ563751; KXJ73379.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182GUH4; -.
DR STRING; 7160.A0A182GUH4; -.
DR VEuPathDB; VectorBase:AALC636_002303; -.
DR VEuPathDB; VectorBase:AALF015987; -.
DR VEuPathDB; VectorBase:AALFPA_057262; -.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd14438; Hip_N; 1.
DR Gene3D; 1.10.260.100; -; 1.
DR Gene3D; 6.10.250.3420; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR034649; Hip_N.
DR InterPro; IPR041243; STI1/HOP_DP.
DR InterPro; IPR006636; STI1_HS-bd.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45883; HSC70-INTERACTING PROTEIN; 1.
DR PANTHER; PTHR45883:SF2; HSC70-INTERACTING PROTEIN; 1.
DR Pfam; PF18253; HipN; 1.
DR Pfam; PF17830; STI1-HOP_DP; 1.
DR Pfam; PF13414; TPR_11; 1.
DR SMART; SM00727; STI1; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803}.
SQ SEQUENCE 398 AA; 42891 MW; BE69A0EE94277943 CRC64;
MACPIDPAEL KKLKIFVDLC AAQPQLLNLP QLSFFKSFIE KLGGKVPEGQ PEFGGAQPKP
EEAKKEQEKE PEEKKEESDP ESDVELDMEG CVEPDNEPEQ PMGDASKEPS EDDIDKANEL
RSKAAAAYSE QNFEDAVKLF TEAIELNPRS ALYHAKRGQA YLKLSKPNAC IRDCTRALEI
NPDSATAYKF RGRANRLLGK WEEAAKDLRQ ACKLDYDEEA DEWLKEVTPN AKKIEQHKLK
MERRRQEKEL RERQERVRKA QEANRKAAEE KARGDGGDGD DGDDFFSGAG GGAGAEDILN
AFKDPEVAAA LQDIMANPSN IGKYQNNPKV MNLVTKIASQ TSQAGGFPGF GGAPGGAGGF
PGGFPGAGGF PGAGAGAGGF PGFGGAPTGG PKTTDDLD
//
