ID A0A182H0L3_AEDAL Unreviewed; 571 AA.
AC A0A182H0L3;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=RP20_CCG019301 {ECO:0000313|EMBL:KXJ71949.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EnsemblMetazoa:AALF019301-PA.1, ECO:0000313|Proteomes:UP000069940};
RN [1] {ECO:0000313|EMBL:KXJ71949.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ71949.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ71949.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ71949.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ71949.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ71949.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:AALF019301-PA.1}
RP IDENTIFICATION.
RC STRAIN=Foshan {ECO:0000313|EnsemblMetazoa:AALF019301-PA.1};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR EMBL; JXUM01101498; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KQ564653; KXJ71949.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182H0L3; -.
DR STRING; 7160.A0A182H0L3; -.
DR EnsemblMetazoa; AALF019301-RA; AALF019301-PA; AALF019301.
DR VEuPathDB; VectorBase:AALC636_002365; -.
DR VEuPathDB; VectorBase:AALF019301; -.
DR VEuPathDB; VectorBase:AALFPA_044930; -.
DR Proteomes; UP000069940; Unplaced.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR InterPro; IPR019819; Carboxylesterase_B_CS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
DR PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Serine esterase {ECO:0000256|ARBA:ARBA00022487};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 22..571
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5039734384"
FT DOMAIN 34..513
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 571 AA; 63975 MW; 22AEF6A0B67B82E5 CRC64;
MLRINVIIPL LVLNFFRDVT AFDDIQCRIW CYSQPAVQTA DGCLCGMKMD GLEAGPFDAF
VGVPFAKPPV GALRFANPIP IDPWEGPLNV TTTKPMCIQK YDIFPLASVR GQEDCLYLNV
YRPKKCRKKK LPVMVYIHGG GYIGESADPR VIGPEKFMDT RKVILVSLQY RLGPFGFLSS
DDCSAPGNFG LKDQSMALRW VQRNIESFGG DRRRVTVFGH SAGGAAVQFH MMSPLSEGLF
SKAISQSGSA LSFWSKQYPD QLGLVRKLAV AAEVEGAVRM NSRELIKALR KVDAAKLLLS
VDKLKFWHNQ PIILFRPVVE KHVDDETFLR EDPRELWATG RYQKIPWMTG YLPDDGIAVL
LSIFTDLLEP FIANQQELLP LLADVPPSSG PALLERFFGG NPIGPENAFA LTEVMSEVGF
KYPMMESILQ HLINDPQSES PVSLYYLNFK GRYSCSTMLP IFTGPDSGAC HAEELMYLFR
QPIQYLDFPK DSPEAAMSRL LVNEWINFAT KGKLSLPQRG GSERPSQQIG MVEFTNSDGP
SGVTTIHRGF EDAKIAELWN LLRWWNVVRV Q
//
