ID A0A182H2Z1_AEDAL Unreviewed; 289 AA.
AC A0A182H2Z1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
GN ORFNames=RP20_CCG020630 {ECO:0000313|EMBL:KXJ71418.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EnsemblMetazoa:AALF020630-PA.1, ECO:0000313|Proteomes:UP000069940};
RN [1] {ECO:0000313|EMBL:KXJ71418.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ71418.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ71418.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ71418.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ71418.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ71418.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:AALF020630-PA.1}
RP IDENTIFICATION.
RC STRAIN=Foshan {ECO:0000313|EnsemblMetazoa:AALF020630-PA.1};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC {ECO:0000256|ARBA:ARBA00006840, ECO:0000256|RuleBase:RU361218}.
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DR EMBL; JXUM01106293; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; JXUM01106294; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KQ565042; KXJ71418.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182H2Z1; -.
DR SMR; A0A182H2Z1; -.
DR STRING; 7160.A0A182H2Z1; -.
DR EnsemblMetazoa; AALF020630-RA; AALF020630-PA; AALF020630.
DR VEuPathDB; VectorBase:AALC636_001862; -.
DR VEuPathDB; VectorBase:AALF020630; -.
DR VEuPathDB; VectorBase:AALFPA_052353; -.
DR Proteomes; UP000069940; Unplaced.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd03127; tetraspanin_LEL; 1.
DR Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR000301; Tetraspanin_animals.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR19282; TETRASPANIN; 1.
DR PANTHER; PTHR19282:SF28; TETRASPANIN; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PIRSF; PIRSF002419; Tetraspanin; 1.
DR PRINTS; PR00259; TMFOUR.
DR SUPFAM; SSF48652; Tetraspanin; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361218};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Transmembrane {ECO:0000256|RuleBase:RU361218};
KW Transmembrane helix {ECO:0000256|RuleBase:RU361218}.
FT TRANSMEM 20..44
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 59..81
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 88..112
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 209..234
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT REGION 258..289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 289 AA; 32043 MW; 96FEA33226784546 CRC64;
MTTDRNDLNM GMRCVKYMIF VINFMFLLTA ILIVTVGTAI GTIFGDFEYF IDSHFFSPAH
LLVAIGIIMM FVSIFGCVGA VKESTAMINI YGVLLAIVFV LELAAAISAF ALQGQVKEMV
RRTLNESMAN YNGNPSVEQS VDFMQQVLEC CGVDSHKDWS FFLQPVANAT ESDVVVPESC
CPPSTLKESC IPYEYGCLDR LQWVVSQSAA LIATGAMTVA FVQILGSICA FMLARTIRRT
KSLRAARRWQ LQQSLGIMTK PHNPSYTQME KSEKNPDSEM YLPNSPSVN
//
