ID A0A182H7G5_AEDAL Unreviewed; 688 AA.
AC A0A182H7G5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=C2h2-type zn-finger protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=RP20_CCG023377 {ECO:0000313|EMBL:KXJ70473.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EnsemblMetazoa:AALF023377-PA.1, ECO:0000313|Proteomes:UP000069940};
RN [1] {ECO:0000313|EMBL:KXJ70473.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ70473.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ70473.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ70473.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ70473.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ70473.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:AALF023377-PA.1}
RP IDENTIFICATION.
RC STRAIN=Foshan {ECO:0000313|EnsemblMetazoa:AALF023377-PA.1};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
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DR EMBL; JXUM01116411; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; JXUM01116412; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KQ565982; KXJ70473.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182H7G5; -.
DR EnsemblMetazoa; AALF023377-RA; AALF023377-PA; AALF023377.
DR VEuPathDB; VectorBase:AALC636_034990; -.
DR VEuPathDB; VectorBase:AALF023377; -.
DR VEuPathDB; VectorBase:AALFPA_075098; -.
DR Proteomes; UP000069940; Unplaced.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1800.20; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 8.
DR InterPro; IPR012934; Znf_AD.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24393:SF15; IP01201P-RELATED; 1.
DR PANTHER; PTHR24393; ZINC FINGER PROTEIN; 1.
DR Pfam; PF07776; zf-AD; 1.
DR Pfam; PF00096; zf-C2H2; 6.
DR SMART; SM00868; zf-AD; 1.
DR SMART; SM00355; ZnF_C2H2; 9.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 4.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS51915; ZAD; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 6.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 8.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU01263};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU01263};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 163..241
FT /note="ZAD"
FT /evidence="ECO:0000259|PROSITE:PS51915"
FT DOMAIN 411..438
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 439..466
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 467..494
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 495..523
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 551..578
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 579..607
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 608..635
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 636..664
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT BINDING 165
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 168
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 214
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 217
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
SQ SEQUENCE 688 AA; 80019 MW; 4CC8D1B0B1B6C50E CRC64;
PVNYPRTLNL IANDLAEPNF QPSFPEILEA IERWKAWVAL QQTEPTRPPD RELKRLLEAL
ESRLTHSQIT LMLQHMEVVG GDADGLWATI AVEMRALKYP PRPEIYWRRG FEEWCQEARD
RFREDPDALT ALQQRYIDYA RERGELDEEV AWIEVDALEL VLNHCRTCLG MLRAADPKAY
LFEPGGMGTT LADKINVCFG TGIDLEERLP KYVCRKCVEK VEEAYALKMQ IDRTDEELKS
LIGEYQKRET ARSNVKNEHR EADTTETTVQ TLQDASPLEV IQEKEQQLSE QLEVPEEEVE
HLEGVVDAEH DVKYSWQVIS DSEQMIVEQV EEHEEEHIDV SEAVQEEVES YDDVMVATEA
DYLEDDIEEQ YVEEETEQNH NFYQCPECRI VLRSHELWET HKARHASEKR YTCEVCSKQF
RSSSTLRIHQ RTHTNERPYV CEICNKSFVQ STNLVYHMNV HQNIRNYPCD QCPYKARNKN
DLNLHKRTHS GARPYICEYC ECTFTTSSNL SKHIKRRHIG EKNFKVCSKA FRTHSQIKAH
GFVHDRNNRP MKCERCPYRT STKSSLSIHM KSHVTTRPYV CPHCKMGFRT SSNMHKHVRN
THEGQRPFKC PECSKTFSTK ETVQKHMVTH TGSKPYACPE CTSTYSWYNG LQKHMKVMHP
GAPIPTEKTM MVASLAAGSM GMGEEVYN
//
