ID A0A182H7P4_AEDAL Unreviewed; 779 AA.
AC A0A182H7P4;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Cleavage and polyadenylation specificity factor subunit 2 {ECO:0000256|RuleBase:RU365006};
DE AltName: Full=Cleavage and polyadenylation specificity factor 100 kDa subunit {ECO:0000256|RuleBase:RU365006};
GN ORFNames=RP20_CCG023536 {ECO:0000313|EMBL:KXJ70452.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EMBL:KXJ70452.1};
RN [1] {ECO:0000313|EMBL:KXJ70452.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ70452.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ70452.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ70452.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ70452.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ70452.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU365006}.
CC -!- SIMILARITY: Belongs to the metallo-beta-lactamase superfamily. RNA-
CC metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
CC {ECO:0000256|RuleBase:RU365006}.
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DR EMBL; KQ566020; KXJ70452.1; -; Genomic_DNA.
DR RefSeq; XP_019528071.1; XM_019672526.2.
DR RefSeq; XP_019931255.1; XM_020075696.1.
DR AlphaFoldDB; A0A182H7P4; -.
DR STRING; 7160.A0A182H7P4; -.
DR GeneID; 109400054; -.
DR GeneID; 109621621; -.
DR KEGG; aalb:109400054; -.
DR KEGG; aalb:109621621; -.
DR VEuPathDB; VectorBase:AALC636_011995; -.
DR VEuPathDB; VectorBase:AALC636_016520; -.
DR VEuPathDB; VectorBase:AALF023536; -.
DR VEuPathDB; VectorBase:AALFPA_042226; -.
DR VEuPathDB; VectorBase:AALFPA_057746; -.
DR VEuPathDB; VectorBase:AALFPA_058209; -.
DR OMA; YVLEHAW; -.
DR OrthoDB; 198429at2759; -.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006378; P:mRNA polyadenylation; IEA:InterPro.
DR CDD; cd16293; CPSF2-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR022712; Beta_Casp.
DR InterPro; IPR027075; CPSF2.
DR InterPro; IPR025069; Cpsf2_C.
DR InterPro; IPR035639; CPSF2_MBL.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR PANTHER; PTHR45922; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2; 1.
DR PANTHER; PTHR45922:SF1; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2; 1.
DR Pfam; PF10996; Beta-Casp; 1.
DR Pfam; PF13299; CPSF100_C; 1.
DR Pfam; PF16661; Lactamase_B_6; 1.
DR Pfam; PF07521; RMMBL; 1.
DR SMART; SM01027; Beta-Casp; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664,
KW ECO:0000256|RuleBase:RU365006};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365006};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW RNA-binding {ECO:0000256|RuleBase:RU365006}.
SQ SEQUENCE 779 AA; 87849 MW; 35DE63EE07B3D55A CRC64;
MTSIIKLHAI SGAMDESPPC YILQVDEVRF LLDCGWDEKF DPNFIKELKK YVHTIDAVLL
SYPDGLHLGA LPYLVGKLGL NCPIYATIPV YKMGQMFMYD LFMSHYNMYD FDLFTLDDVD
AAFDRIIQLK YNQSVSLKGK GYGITITPLP AGHLIGGTIW KVMKVGEEDI VYATDFNHKK
ERHLNGCELE KLQRPSLLIT DAYNAKYQQA RRRARDEKFM TNILQTLRNN GNVLVTVDTA
GRVLELAHML DQLWKNKESG LMAYSLALLN NVSYNVVEFA KSQIEWMSDK LMKSFEGARN
NPFQFKHLRL CHTMADLAKV PSPKVVLASS ADMESGFSRE LFVQWASNAN NSIIITCRSS
PGTLSRDLIE NGGNGRKIEL DVRRRVELEG AELEEYMRTE GEKHNRSIIK SDMDLDSSSD
SDDELEMSVI TGKHDIVVRP EGRSHTGFFK SSKKQYAMFP FHEEKIKFDE YGEIIQPDDY
KMIDLGPDGG FEDNKENQIK PEDIKKEKGE ELSVLDKPTK CISSRKLVEI NAQVQFIDFE
GRSDGESMLK ILSQLRPRRV VVIRGSPQNT AHIAEHCQLN IGARVFTPNR GEVIDATTET
HIYQVRLTEA LISQLEFQKG KDAEVAWVDA QIVIRNKQFS AQGAEDDVSG PLSGMTNNAT
TNNAIAAAAA AASDTPMDVD QVEGGDDKSD RQILTLEPMK NEELPAHNSV FINELKLIDF
KQILMKANIN SEFSGGVLWC SNGTVALRRV DTGKVTVEGC LSEEYYKIRE LLYEQYAIV
//
