ID A0A182HA26_AEDAL Unreviewed; 1306 AA.
AC A0A182HA26;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Transient receptor ion channel domain-containing protein {ECO:0000259|SMART:SM01420};
GN ORFNames=RP20_CCG025056 {ECO:0000313|EMBL:KXJ80443.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EMBL:KXJ80443.1};
RN [1] {ECO:0000313|EMBL:KXJ80443.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ80443.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ80443.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ80443.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ80443.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ80443.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KQ560896; KXJ80443.1; -; Genomic_DNA.
DR STRING; 7160.A0A182HA26; -.
DR VEuPathDB; VectorBase:AALC636_037934; -.
DR VEuPathDB; VectorBase:AALF025056; -.
DR VEuPathDB; VectorBase:AALFPA_063896; -.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0034703; C:cation channel complex; IEA:UniProt.
DR GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR013555; TRP_dom.
DR InterPro; IPR002153; TRPC_channel.
DR NCBIfam; TIGR00870; trp; 1.
DR PANTHER; PTHR10117; TRANSIENT RECEPTOR POTENTIAL CHANNEL; 1.
DR PANTHER; PTHR10117:SF47; TRANSIENT-RECEPTOR-POTENTIAL-LIKE PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF08344; TRP_2; 1.
DR PRINTS; PR01097; TRNSRECEPTRP.
DR SMART; SM00248; ANK; 2.
DR SMART; SM01420; TRP_2; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 177..239
FT /note="Transient receptor ion channel"
FT /evidence="ECO:0000259|SMART:SM01420"
SQ SEQUENCE 1306 AA; 146317 MW; 68C25A32F70FBD9F CRC64;
MAADVDDAPL PAGHPDRFPG HPEPAGDPEL DYYRFRYGLR LFSGLPFIRI LQRAHRRHHI
NINCVDPLGR GALTLAIDGE NLEMVELLII MQVDTKDGLL QAINAEFVEA VELLLEHEEL
IHKEGELYSW QKVDINTATF TPDITPLMLA AHKNNYEILK ILLDRGATLP MPHDVKCGCD
ECIRRSSEDS LRHSLARVNE YRALASPSLI ALSSQDPLLT AFQLSWELRN LAFAEQECKA
QYLELRRQCQ SFAVDLLDQS RSSQELAIIL NYDPESPPYM DGDHMKLTRL ELAIDYKQKK
FVAHPNIQQL LAAMWYEGVP GFRRKSAMEK IAIITKVAVL FPFYCMMYMI APSCETAKFM
RKPFMKFLIH ASSYLFFLFL LILVSQRAEV QIVLLFGTDS MKRALQEELA RQRGNGPTYL
ECLVVIYVIG FIWEETQEIF IEGIRSYLKN MWNFIDFSRN FLYCCVAMLR VVAYIQQTSQ
INNDPSTAYI AREHWDDFDP QLIAEGLFAA ANIFSALKLV HLFSINPHLG PLQISLGRMV
IDIVKFFFIY SLVLFAFACG LNQLLWYFAD LEKSKCYSLK GGLPDWDNQG DACMKWRRFG
NLFESSQSLF WASFGMVGLE SFELAGIKSY TRFWGLLMFG SYSVINVIVL LNLLIAMMSN
SYAMIDEHSD TEWKFARTRL WMSYFEESST LPPPFNIFPN MKHLMRLCGK KKRRDIKRES
TIRRKEDKER TERYTNVMRS LVWRYVSAMH RKMEENAVTE DDINEVKGEI SAMRYELLEI
FEKNGMDVSA ADRKEKAVLA KRMKIWERRL MKDFHVAPVD MQDNALDEED EEEDANPLAR
FRRVARKVAT QTTSAKWGQV MSGVGIETNS QIGRCKNRDS FRQQQQLQKA MNEARRLVER
SPLPRSRSAS PMMDGYEDET TNTLLQLINQ LAEETGGDVS PGNTLHTLGK HSRSTTPLNM
LTAQLQTMLS KSPSPMTMKS LKTGDTKSPG NLNRSPAPRK EGKSLPSING SMPTSPEPSA
PVETKPTLGV RSPPTIKSPP PAKSPIQPIQ SPPPTIRITE PHLIKKSDSK DSLVDAVPTV
EVKPPTPQPS KPPTPVLPKS DAPPPSEPMK SPEAKPSETV VHADDPAPLV AGVNSPPKVI
KRKAPTPSAS DAPPPAGDIS VSRPVAAKPQ PGQGMLPPPP SKEEQPNISI PVLSTTPATP
LPATKNLGAT PKKSPPPIAP KPQSPPPAPA VPPKVASPPP TVKVELMSEQ QPSDVTSSTE
QLIGSSSSSP PPADAARAVS SPTCLRPINK IADVKTIKRQ PKSGWL
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