ID A0A182HAY4_AEDAL Unreviewed; 636 AA.
AC A0A182HAY4;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 13-SEP-2023, entry version 36.
DE RecName: Full=Neural adherens junction protein plakophilin {ECO:0008006|Google:ProtNLM};
GN ORFNames=RP20_CCG025583 {ECO:0000313|EMBL:KXJ69873.1};
OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7160 {ECO:0000313|EnsemblMetazoa:AALF025583-PA.1, ECO:0000313|Proteomes:UP000069940};
RN [1] {ECO:0000313|EMBL:KXJ69873.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ69873.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ69873.1};
RX PubMed=26483478; DOI=10.1073/pnas.1516410112;
RA Chen X.G., Jiang X., Gu J., Xu M., Wu Y., Deng Y., Zhang C., Bonizzoni M.,
RA Dermauw W., Vontas J., Armbruster P., Huang X., Yang Y., Zhang H., He W.,
RA Peng H., Liu Y., Wu K., Chen J., Lirakis M., Topalis P., Van Leeuwen T.,
RA Hall A.B., Jiang X., Thorpe C., Mueller R.L., Sun C., Waterhouse R.M.,
RA Yan G., Tu Z.J., Fang X., James A.A.;
RT "Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals
RT insights into its biology, genetics, and evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:E5907-E5915(2015).
RN [2] {ECO:0000313|EMBL:KXJ69873.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Foshan {ECO:0000313|EMBL:KXJ69873.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:KXJ69873.1};
RA Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:AALF025583-PA.1}
RP IDENTIFICATION.
RC STRAIN=Foshan {ECO:0000313|EnsemblMetazoa:AALF025583-PA.1};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- SIMILARITY: Belongs to the beta-catenin family.
CC {ECO:0000256|ARBA:ARBA00005462}.
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DR EMBL; JXUM01123618; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KQ566737; KXJ69873.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A182HAY4; -.
DR STRING; 7160.A0A182HAY4; -.
DR EnsemblMetazoa; AALF025583-RA; AALF025583-PA; AALF025583.
DR VEuPathDB; VectorBase:AALC636_010812; -.
DR VEuPathDB; VectorBase:AALF025583; -.
DR VEuPathDB; VectorBase:AALFPA_045878; -.
DR Proteomes; UP000069940; Unplaced.
DR Proteomes; UP000249989; Unassembled WGS sequence.
DR GO; GO:0098609; P:cell-cell adhesion; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR028435; Plakophilin/d_Catenin.
DR PANTHER; PTHR10372:SF27; ADHERENS JUNCTION PROTEIN P120; 1.
DR PANTHER; PTHR10372; PLAKOPHILLIN-RELATED; 1.
DR Pfam; PF00514; Arm; 4.
DR SMART; SM00185; ARM; 6.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 3.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Reference proteome {ECO:0000313|Proteomes:UP000249989}.
FT REPEAT 89..133
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 133..176
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 408..445
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 17..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 555..636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 555..584
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 636 AA; 70061 MW; 810CACCB94CA5171 CRC64;
MQNLQIHNHV FLQHHIITSP GGNNRPGAGG PDGPDLDDQR QMKWRDPNLT EVIGFLSHPN
NAIKANAAAY LQHLCYMDDP NKQRTRTLGG IPPLVKLLGH ENTDVYRNAC GALRNLSYGR
QNDENKRAIN SAGGIQALIH LLRRTSESDI KELVTGIIWN MSSCEDLKRF IIDDAIIVIV
SYIIIPHSGW DPTNPGETCW STVFRNASGI LRNVSSAGEY ARKKLRECEG LVDSLLYVVR
IAIEKSNIGN KIVENCVCIL RNLSYRCQEV EDPNYDKNPI PHYSSADGSH GSAIVSAASS
KGENLGCFGA SKKKKEQQAA AAAAQQAADA KDHSSANGDP ARMAYKNTAH YKGAEQLWQP
DVVHSYLALL QSCSNPETLE AAAGALQNLA ACYWQPSIEI RATVRKEKGL PILVELLRME
VDRVVCAVAT ALRNLAIDQR NKELIGKYAM RDLVQKLPSG NPQCDQGTSD DTIAAVLATL
NEVIKKNAEF ARSLLEAGGV ERLMNMTRQR LKYTPRVLKF AGQLLFTMWQ HQELRDMYKK
HGWKEQDFVT KTIASRNVNS SNGGSYSDNS PNSPNNTLNR PMASQGGTRY EDRTMKRQQA
SNNGGQAMSL PPSDGAVKMG KSGAAARVES SHRESF
//
