ID A0A182HKG1_ANOAR Unreviewed; 518 AA.
AC A0A182HKG1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Importin subunit alpha {ECO:0000256|PIRNR:PIRNR005673};
OS Anopheles arabiensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7173 {ECO:0000313|EnsemblMetazoa:AARA001741-PA.1, ECO:0000313|Proteomes:UP000075840};
RN [1] {ECO:0000313|Proteomes:UP000075840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dongola {ECO:0000313|Proteomes:UP000075840};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles arabiensis DONG5_A.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AARA001741-PA.1}
RP IDENTIFICATION.
RC STRAIN=Dongola {ECO:0000313|EnsemblMetazoa:AARA001741-PA.1};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- SIMILARITY: Belongs to the importin alpha family.
CC {ECO:0000256|ARBA:ARBA00010394, ECO:0000256|PIRNR:PIRNR005673}.
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DR EMBL; APCN01000828; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A182HKG1; -.
DR EnsemblMetazoa; AARA001741-RA; AARA001741-PA; AARA001741.
DR VEuPathDB; VectorBase:AARA001741; -.
DR VEuPathDB; VectorBase:AARA21_010571; -.
DR OrthoDB; 916229at2759; -.
DR Proteomes; UP000075840; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.20.5.690; Importin-alpha, importin-beta-binding domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032413; Arm_3.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR002652; Importin-a_IBB.
DR InterPro; IPR036975; Importin-a_IBB_sf.
DR InterPro; IPR024931; Importin_alpha.
DR PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR PANTHER; PTHR23316:SF28; IMPORTIN SUBUNIT ALPHA; 1.
DR Pfam; PF00514; Arm; 7.
DR Pfam; PF16186; Arm_3; 1.
DR Pfam; PF01749; IBB; 1.
DR PIRSF; PIRSF005673; Importin_alpha; 1.
DR SMART; SM00185; ARM; 8.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 3.
DR PROSITE; PS51214; IBB; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR005673};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005673}.
SQ SEQUENCE 518 AA; 57325 MW; C60CCD224D523845 CRC64;
MASIDSQSKN RMQGFKNKGK DQDEMRRRRT EVTVELRKNK REETILKRRN VPQTTESTDE
EDYTLQSNLK KLVEKAGNSS DKEGQLAAVQ AARRLLSSDR NPPINNLIDS GILPILVNCL
EQDDNQVLQF EAAWALTNIA SGTAAQTNQV VRAGAVPLFL RLLNSPAPNV CEQAVWALGN
IIGDGPSLRD YVIKLGVVQP LLSFIQPEIP IPFLRNVTWV IVNLCRNKDP PPPAATILEI
LPALNMLIHH TDINILVDTV WALSYLTDGG NEQIQLVIDS GVVPKLIPLL SHVEVKVQTA
ALRAVGNIVT GSDDQTQVVL NCDALSHFPK LLTHSKDKIR KEAVWFLSNI TAGNQSQVQA
VIDAGLLPKV IENLKHGDFH TQKEAAWAIS NLTISGNREQ VAQLINDGAV PPFCDLLMCQ
DCQVINVVLD GINNMLKLAG PHAEHVANLI EECDGVSKIE VLQNHENVEI YKLAYDIIEQ
FFSDDVDEAV LEDLRPAADE NAFQFNQNPN IPRDGFNF
//
