ID   A0A182HT33_ANOAR        Unreviewed;      1233 AA.
AC   A0A182HT33;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=CDK5 regulatory subunit-associated protein 2 {ECO:0000256|ARBA:ARBA00020479};
OS   Anopheles arabiensis (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7173 {ECO:0000313|EnsemblMetazoa:AARA004438-PA.1, ECO:0000313|Proteomes:UP000075840};
RN   [1] {ECO:0000313|Proteomes:UP000075840}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dongola {ECO:0000313|Proteomes:UP000075840};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles arabiensis DONG5_A.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AARA004438-PA.1}
RP   IDENTIFICATION.
RC   STRAIN=Dongola {ECO:0000313|EnsemblMetazoa:AARA004438-PA.1};
RG   EnsemblMetazoa;
RL   Submitted (AUG-2022) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; APCN01000404; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A182HT33; -.
DR   EnsemblMetazoa; AARA004438-RA; AARA004438-PA; AARA004438.
DR   VEuPathDB; VectorBase:AARA004438; -.
DR   VEuPathDB; VectorBase:AARA21_000267; -.
DR   Proteomes; UP000075840; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005815; C:microtubule organizing center; IEA:InterPro.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
DR   InterPro; IPR042791; CDK5RAP2.
DR   InterPro; IPR012943; Cnn_1N.
DR   PANTHER; PTHR46930; CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 2; 1.
DR   PANTHER; PTHR46930:SF1; CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 2; 1.
DR   Pfam; PF07989; Cnn_1N; 1.
PE   4: Predicted;
KW   Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT   DOMAIN          65..155
FT                   /note="Centrosomin N-terminal motif 1"
FT                   /evidence="ECO:0000259|Pfam:PF07989"
SQ   SEQUENCE   1233 AA;  137663 MW;  320365571E59A6CE CRC64;
     MSGIFKYTPN RTAASTPNRR SAFGTGFGSP GVHQDATMDN SYAMGFRSPS INALTGHGSP
     VQVRSLRDNE EEISTLRKEN FNLKLRIYFL EQKAGICTDN DTPGGLGVTS SSASNTSCDG
     NYLKQNIDLK VEVESLRQDL QSKHDLLCQA VKAMEVLEES HKKAEERHRE LVNDLNHRIE
     NHQAEIRSLE LMAGELQKQH RELQLSTSLR GDPELQQQQQ QHAAEEAKEG MTTRDNVGES
     LLDFLDAVQQ HSELSVQEKL KVLEMENAVR QCQERNEQLT RQVEQLQATI EEKASKISQL
     EMELGELRFE NAELREESEK PQSNVEIDRL KKQNFDIRAE LAEKLCVLDD TETKLKEKTL
     ECTKTCKMVE KLIKTITEQD KELEKLKRNS NISLHSEHGM NGGATGALGG VAALAVPEIV
     DQDRKPVSQA EYDALVQRAK LLQQKNDTLI HKLCGNGGAG DHRNDRNIII KQLNDELIKA
     REEAEKAQKW RKEYADLCAI STHRLEELAG FLDSLLRNKE LIGSLSTDSR KAIRNAVDRS
     LDLSRSLNMS ISVTGLSLIG TNNNSLAQLS CLSGYLDQSA VLEHGEHSSA GDDVDDEHDK
     ENRASNVKGQ TIQTGGHGAL FGGLNQTKQM IETLRAENKA LRGELMEQQQ LQQQQHQQRT
     RRRESKERKS VPIEPISDSE AWSEPDRGVS LARIGLEDSS SALLRQKNGP AGGPTASLSS
     PTSGAAALEL SSTSDNEPGL LAAVGLTSQR KSATVAEMKQ LQETVASLSK ELQDKNGTLL
     TVQSQLVDLD SELQRERIRA AKAQTEATET RQLSERWERD AAVHREQAEQ AAQRLAALEG
     DIRQRDALIE KLRKEREQAA VDLRVAMMKL ETMQSEYGEL QQRHRRELDA MLAKEQQQLE
     ELRQSLTESF RNELQLKQQS FDTALAQNYI SKNIHQEKVR ELDELHYRLE DAHNDLSAMA
     EAEEQLRRQL ADCERSAAAM KKSLDEATLQ ASKAAIERTK ALNEKRQLET ELGFAHDELE
     QLKVEKNALN EQLQTIIRTQ QQQHPRSPRG SGGGGNQSAS GTDEEITPGV RRQLENSSPD
     LGIESDPGRL SNVELKFATS PQQRPLLKTL ELTKSMSNLL LNPNQEVKPE SSGESSKGAA
     GGEQQEGVGG GGADKTTVIH HDCAKIEVDY RDLMHRYNKT RHYLAVAYDK IKSSNKVKKQ
     LEIEVKQQIH KTNVVLKTVQ RNLDSGNDGA GEH
//