ID   A0A182I681_ANOAR        Unreviewed;      1136 AA.
AC   A0A182I681;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 2.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:AARA009084-PA.2};
OS   Anopheles arabiensis (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7173 {ECO:0000313|EnsemblMetazoa:AARA009084-PA.2, ECO:0000313|Proteomes:UP000075840};
RN   [1] {ECO:0000313|Proteomes:UP000075840}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dongola {ECO:0000313|Proteomes:UP000075840};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles arabiensis DONG5_A.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AARA009084-PA.2}
RP   IDENTIFICATION.
RC   STRAIN=Dongola {ECO:0000313|EnsemblMetazoa:AARA009084-PA.2};
RG   EnsemblMetazoa;
RL   Submitted (AUG-2022) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; APCN01003583; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A182I681; -.
DR   EnsemblMetazoa; AARA009084-RA; AARA009084-PA; AARA009084.
DR   VEuPathDB; VectorBase:AARA009084; -.
DR   VEuPathDB; VectorBase:AARA21_001440; -.
DR   Proteomes; UP000075840; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:UniProt.
DR   GO; GO:0048468; P:cell development; IEA:UniProt.
DR   GO; GO:0010604; P:positive regulation of macromolecule metabolic process; IEA:UniProt.
DR   GO; GO:0051173; P:positive regulation of nitrogen compound metabolic process; IEA:UniProt.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR   GO; GO:0048731; P:system development; IEA:UniProt.
DR   CDD; cd08310; Death_NFkB-like; 1.
DR   CDD; cd01177; IPT_NFkappaB; 1.
DR   CDD; cd07884; RHD-n_Relish; 1.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.60.40.340; Rel homology domain (RHD), DNA-binding domain; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR028320; iASPP.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002909; IPT_dom.
DR   InterPro; IPR033926; IPT_NFkappaB.
DR   InterPro; IPR000451; NFkB/Dor.
DR   InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR   InterPro; IPR032397; RHD_dimer.
DR   InterPro; IPR011539; RHD_DNA_bind_dom.
DR   InterPro; IPR037059; RHD_DNA_bind_dom_sf.
DR   PANTHER; PTHR24164; RELA-ASSOCIATED INHIBITOR; 1.
DR   PANTHER; PTHR24164:SF4; RELA-ASSOCIATED INHIBITOR; 1.
DR   Pfam; PF12796; Ank_2; 2.
DR   Pfam; PF16179; RHD_dimer; 1.
DR   Pfam; PF00554; RHD_DNA_bind; 1.
DR   PRINTS; PR00057; NFKBTNSCPFCT.
DR   SMART; SM00248; ANK; 6.
DR   SMART; SM00429; IPT; 1.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   SUPFAM; SSF49417; p53-like transcription factors; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 3.
DR   PROSITE; PS50088; ANK_REPEAT; 3.
DR   PROSITE; PS50254; REL_2; 1.
PE   4: Predicted;
SQ   SEQUENCE   1136 AA;  125266 MW;  118C707F540458A1 CRC64;
     MSTLLNLDSY RHELYEQQQL LGTSPIQYTV LSMDTPSPSS SAAAAAVVSV GEFTLGPGRT
     YASALSPSSS SASPSSPSSV ASPNSRASNM SPESSASDQS AAYTLQNLNL SSSAGTMNYP
     GMGYQQQQQQ QQQQQHQHQQ LQQQQHHYYT PQLLNLDQEH LQTQTFTYVT SSNEAFAAPE
     PNYSEPHLVI LEQPVDKFRF RYQSEMHGTH GSLMGSRTEK SKKTFPTVEL RGYGGEAKVR
     CSLYQVDPQR RAPHSHHLVI KSGELDLIDP HDLDVGGAAG AAEPSEGVGG DGKYVATFQG
     MGIIHTAKKF IAEELYKKLR KHRLCELNRE PTEREEQQMQ KEAAVMARTM NLNQVCLCFR
     AYRVEPGTGR WVPICEPVYS NPINNMKSAL TGELKICRLS TTVSGVDGGE EVFMFVEKVC
     KNNIKIRFYE LDEYDQEVWQ EMAIFSEADV HHQYAIAFKT PPYRHKDITE PVEVLMQLFR
     PRDRCQSEPV LFKYKPRPGM MVVPGAGAAS GASRKRLRIS SGNVSSEIPT VIQNDPNGPV
     GPAGVGGGGG GGGGGGGGGG AIGSGSTTRL PPLHQPFPML ANHAGGGAIP EGQEPTSTTS
     LTTSAHHTDL MSGIGSTTTI SKELTKASII QEILNIPTTI ASDVAFDSSD FPCNSEEFNK
     LIQEIGNQQD LVKLETDAET AGGGATDTES VLGRAIADLV ASGDDSRQGE MLRKLLALIK
     LFAKDVNRSR QLLASHWTAA NQQQLNCLHA AIRRNDTTIA CKLIELLHEY QLAEELLDLP
     NDRNETGLHL AVSCNSEPIV KALLGAGAKL HFCDYRGNTP LHRAVVENVP DMVRLLLLQR
     RPGQPGGLRL DCTNDDGLTA LQAAVYARNL KITRILLEAG ASVREKDLKH GNNILHIAVD
     NDALDIVHYI LEEVKEELGR ERNNAGYTPL QLADAKSHTG QGNNKLIVRE LLRHYPDGLQ
     KEVKKEVDAT EDDEEEEEEE EEEEDEDEEG EEHGQREASA PSSNVLDSMD LINGERATIA
     RLLEEHEPEV EPQRKTTKRS DSGPDRTEPD TLFDEQCLEE LCRLLDAGNG WRELGSLLDF
     HSFFTVWEQA PSPARMLLGY FEMQQLHLDR LIDMLRVLEL RDPIRSIDEM ICRRMK
//