ID A0A182I778_ANOAR Unreviewed; 543 AA.
AC A0A182I778;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 08-NOV-2023, entry version 41.
DE RecName: Full=Cell division control protein 73 C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Anopheles arabiensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7173 {ECO:0000313|EnsemblMetazoa:AARA009432-PA.1, ECO:0000313|Proteomes:UP000075840};
RN [1] {ECO:0000313|Proteomes:UP000075840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dongola {ECO:0000313|Proteomes:UP000075840};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles arabiensis DONG5_A.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AARA009432-PA.1}
RP IDENTIFICATION.
RC STRAIN=Dongola {ECO:0000313|EnsemblMetazoa:AARA009432-PA.1};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CDC73 family.
CC {ECO:0000256|ARBA:ARBA00010427}.
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DR EMBL; APCN01003368; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A182I778; -.
DR EnsemblMetazoa; AARA009432-RA; AARA009432-PA; AARA009432.
DR VEuPathDB; VectorBase:AARA009432; -.
DR VEuPathDB; VectorBase:AARA21_014661; -.
DR OrthoDB; 180759at2759; -.
DR Proteomes; UP000075840; Unassembled WGS sequence.
DR GO; GO:0016593; C:Cdc73/Paf1 complex; IEA:InterPro.
DR GO; GO:0006368; P:transcription elongation by RNA polymerase II; IEA:InterPro.
DR Gene3D; 3.40.50.11990; RNA polymerase II accessory factor, Cdc73 C-terminal domain; 1.
DR InterPro; IPR007852; Cdc73/Parafibromin.
DR InterPro; IPR031336; CDC73_C.
DR InterPro; IPR038103; CDC73_C_sf.
DR InterPro; IPR032041; Cdc73_N.
DR PANTHER; PTHR12466; CDC73 DOMAIN PROTEIN; 1.
DR PANTHER; PTHR12466:SF8; PARAFIBROMIN; 1.
DR Pfam; PF05179; CDC73_C; 1.
DR Pfam; PF16050; CDC73_N; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT DOMAIN 1..296
FT /note="Paf1 complex subunit Cdc73 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16050"
FT DOMAIN 380..531
FT /note="Cell division control protein 73 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05179"
SQ SEQUENCE 543 AA; 61689 MW; 395EF0AF01D05AA2 CRC64;
MADPLSLLRQ YNINKKEIIE RDGQIIFGEF SWPKNVKTNY LKYGSGKKGA PKEYYTLECL
LYILKNVGLQ HSVYVRQAAA EDIPAVNRPD RKELLQYLNG ETNTCASIDK SAPLEIPTQI
KRPAESDGLD SLAKKARYED TQVQKVKEQL AARLDVNKKE ASVNIDNIKS LSETMSVEKI
AAIKAKRLAN KKVTIKRTDN DDAMGVGPDL RVILDFDVDS TKDIVSRERQ WRTRTTILQS
NGKIFAKNIF AILQSIKNRE EGRGRPAQQP VKLPEPPRVI RPQPQPTQYN RYDQERFNRQ
KEETEGFKID TMGTYHGMSL KLVTQGQAGQ NKAQPNSLNN NNSSSNNNLS ASMPPGRPKE
LIPTAQARML AQNAPSKRTS RTPIIIIPAA TTSLITMYNA RDVLQDLKFI TTDEKKRGGC
SRETEVLIQR QKAGNLTVPY RVIDNPSKLT AHDWNRVVAV FVMGPAWQFK GWPWDGNPVE
IFSKIAAFHL RYDDLKLDAN VAKWAVTVLN ISRTKRHLDK ACLMAFWEKL DLYMTKYKPD
LRF
//
