ID   A0A182ICP2_ANOAR        Unreviewed;       520 AA.
AC   A0A182ICP2;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:AARA011359-PA.2};
OS   Anopheles arabiensis (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7173 {ECO:0000313|EnsemblMetazoa:AARA011359-PA.2, ECO:0000313|Proteomes:UP000075840};
RN   [1] {ECO:0000313|Proteomes:UP000075840}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dongola {ECO:0000313|Proteomes:UP000075840};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles arabiensis DONG5_A.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AARA011359-PA.2}
RP   IDENTIFICATION.
RC   STRAIN=Dongola {ECO:0000313|EnsemblMetazoa:AARA011359-PA.2};
RG   EnsemblMetazoa;
RL   Submitted (AUG-2022) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the amidase family.
CC       {ECO:0000256|ARBA:ARBA00009199}.
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DR   EMBL; APCN01005736; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A182ICP2; -.
DR   EnsemblMetazoa; AARA011359-RA; AARA011359-PA; AARA011359.
DR   VEuPathDB; VectorBase:AARA011359; -.
DR   VEuPathDB; VectorBase:AARA21_013151; -.
DR   OrthoDB; 146362at2759; -.
DR   Proteomes; UP000075840; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1300.10; Amidase signature (AS) domain; 1.
DR   InterPro; IPR020556; Amidase_CS.
DR   InterPro; IPR023631; Amidase_dom.
DR   InterPro; IPR036928; AS_sf.
DR   PANTHER; PTHR43372; FATTY-ACID AMIDE HYDROLASE; 1.
DR   PANTHER; PTHR43372:SF1; LD38433P; 1.
DR   Pfam; PF01425; Amidase; 1.
DR   PIRSF; PIRSF001221; Amidase_fungi; 2.
DR   SUPFAM; SSF75304; Amidase signature (AS) enzymes; 1.
DR   PROSITE; PS00571; AMIDASES; 1.
PE   3: Inferred from homology;
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128}.
FT   ACT_SITE        128
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
FT   ACT_SITE        203
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
FT   ACT_SITE        227
FT                   /note="Acyl-ester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
SQ   SEQUENCE   520 AA;  57970 MW;  E3DDB5BD4740C375 CRC64;
     MARNRMLVYF FTLLHLVIDK VLYLCLKWYW GPSKRRCPTL QRKRLLVTYS AVELARMIRT
     REVSCYDVIS AFIDRLNEVN PLVNAVLDGP FIDALEEARR IDERLQQGTI GEAELAAKPF
     LGVPFTTKDS TAVKDRLHTL GIVARRTVRA NNDAECVRLM KAAGAIIIAT TSIPEINRWQ
     ETRNNIIGQT NNPYDNRRTV GGSSGGEGAL LAACGTPIGL GTDIGGSIRM PAFYCGVYGH
     KPTTGIINTR GCSLRTGREP STMVVAGPMT RYATDLLPLM QVLVGPEKCT SLRFDEPVDV
     RKLRYFYITE SGDIKCSAVQ PSLQKAMDRV VQHFGQIAPA GVRKVTLSGT DRTTNMWRYW
     MTQEPANFGT LLGNGKPLSP LVELAKKLTG RSEYTMASIY SLMDTLLPQE KEDVIKELTR
     RCDQELTELL GDDGVLFYHS TTHAAPYHYG AFVNVYNFSY WCLFNVLHVP ATQVPLGLDG
     DGLPLGIQVV ASRNRDRHCL AVAEEIERVF NGRIPPFIVD
//