GenomeNet

Database: UniProt
Entry: A0A182IEI8_ANOAR
LinkDB: A0A182IEI8_ANOAR
Original site: A0A182IEI8_ANOAR 
ID   A0A182IEI8_ANOAR        Unreviewed;       855 AA.
AC   A0A182IEI8;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   18-SEP-2019, entry version 20.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:AARA012015-PA};
OS   Anopheles arabiensis (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Anophelinae; Anopheles.
OX   NCBI_TaxID=7173 {ECO:0000313|Proteomes:UP000075840, ECO:0000313|VectorBase:AARA012015-PA};
RN   [1] {ECO:0000313|Proteomes:UP000075840, ECO:0000313|VectorBase:AARA012015-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dongola {ECO:0000313|Proteomes:UP000075840,
RC   ECO:0000313|VectorBase:AARA012015-PA};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA   Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA   Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA   Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Anopheles arabiensis DONG5_A.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:AARA012015-PA}
RP   IDENTIFICATION.
RC   STRAIN=Dongola {ECO:0000313|VectorBase:AARA012015-PA};
RG   VectorBase;
RL   Submitted (JUN-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; APCN01005204; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   VectorBase; AARA012015-RA; AARA012015-PA; AARA012015.
DR   Proteomes; UP000075840; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 2.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 2.
DR   Pfam; PF01007; IRK; 2.
DR   Pfam; PF17655; IRK_C; 2.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 2.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000075840};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075840};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM    129    150       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    209    232       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    526    549       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    609    632       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       92    237       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      245    413       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   DOMAIN      491    637       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      644    814       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      459    483       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   855 AA;  97500 MW;  7D1001FDB4471F3D CRC64;
     MSLDSLDSLT GSPYSARKNW LKAQEHQQHI EYRFSRPIKI VDYDKERYSW SAPDTEPKFP
     ITIRSARSLQ SLRMRRDPQH QGTRAIKARR VINKKGEGNV HLAHLPQRSL RYVRDIATTL
     VDEQWRYTLM LFVLSFVASW IFFAVLWYLI AYAHGDLLKD PTTGERLGDG NKPCVEGTTS
     FTGFLLFSVE TQVSTGYGVI VPTEECPEAF FLLLIQIVFG LVIGGAMVGV VYAKMIRLPK
     RSCEMKFSKR AVICMRDGRL CLVFRVCDHK QQHVIGTQIT ATMLEPKRHA GSNVIERYET
     RLRLQNNGRV LPLWPITVCH VIDRYSPLYD TSAADLLDRR FEIVITMTGS TMTTGQSTQA
     RTSYIPVEIL WGHRFQNIIE YDPKRECYVA MNEQLDLLEE VDTPLCSARQ LEEVFDELQN
     EHHRGADDYP SADDDSRLGV GSWEYLAYQC VRSLKSSSTM DSSSAQEGLR KRPKSSDSDS
     QDQLTLDTRV VNKIGERNVR IYNLPQRSIR FVKDLVTTLV EEQWRYVLFV FVASYVGSWV
     FFAGLWYILS YAHGDLIQDS PTGERLGDGV MPCVQGATNF IGFVLFSMET QISTGYGEKV
     PTEECPESFG LLTIQLIVGL LIDGAILGVV YAKLVRPPQK ISEMKFSRRA VICQRDGQLC
     FVFRICDRKW QHAIETKVTA VLLASRRTAE GEEIEKNESY LKLENDGRLV LLWPVTACHV
     IDRDSPLYDV SAADLLERKL EIVITITGGT MTTGQINQAR TSYVPSEICW GHRFRDIVEY
     DARKQSYVAV NERMHEIEQV DTPLCSARQL DMLKKRLQRD VKQDRLPASA RQESSIIFKD
     NVNSDSEPKV ADSIV
//
DBGET integrated database retrieval system