GenomeNet

Database: UniProt
Entry: A0A182IRU9_9DIPT
LinkDB: A0A182IRU9_9DIPT
Original site: A0A182IRU9_9DIPT 
ID   A0A182IRU9_9DIPT        Unreviewed;      5040 AA.
AC   A0A182IRU9;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   28-FEB-2018, entry version 11.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:AATE004286-PA};
OS   Anopheles atroparvus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Anophelinae; Anopheles.
OX   NCBI_TaxID=41427 {ECO:0000313|Proteomes:UP000075880, ECO:0000313|VectorBase:AATE004286-PA};
RN   [1] {ECO:0000313|Proteomes:UP000075880, ECO:0000313|VectorBase:AATE004286-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EBRO {ECO:0000313|Proteomes:UP000075880,
RC   ECO:0000313|VectorBase:AATE004286-PA};
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA   Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA   Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C.,
RA   Murphy C., Pearson M., Poon T.W., Priest M., Roberts A., Saif S.,
RA   Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Anopheles atroparvus EBRO.";
RL   Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:AATE004286-PA}
RP   IDENTIFICATION.
RC   STRAIN=EBRO {ECO:0000313|VectorBase:AATE004286-PA};
RG   VectorBase;
RL   Submitted (JUN-2016) to UniProtKB.
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DR   VectorBase; AATE004286-RA; AATE004286-PA; AATE004286.
DR   Proteomes; UP000075880; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 2.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000075880};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075880};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4369   4389       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4555   4576       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4645   4667       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4835   4857       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4913   4936       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       94    148       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      155    200       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      210    264       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      270    328       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      336    394       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      577    803       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1016   1218       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1436   1652       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   COILED      460    480       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   5040 AA;  569209 MW;  40B49720E9974943 CRC64;
     MAEAEGGSEQ DDVSFLRTED MVCLSCTATG ERVCLAAEGF GNRHCFLENI ADKNIPPDLS
     QCVFVIEQAL SVRALQELVT AAGSETGKGT GSGHRTLLYG NAILLRHNNS DMYLACLSTS
     SSNDKLSFDV GLQEHSQGEA CWWTVHPASK QRSEGEKVRV GDDLILVSVA TERYLHTTKE
     NDLSIVNASF HVTHWSVQPY GTGISRMKYV GYVFGGDVLR FFHGGDECLT IPSTWSVDAG
     QNIVVYEGGS VMSQARSLWR LELARTKWAG GFINWSHPMR IRHLTTGRYL GVNDNNELIL
     MTRDQATTSQ TAFVLRLEKD DQKVVLEDKD LEIIGAPIIK YGDSTVIMQH YESGLWVSYK
     SYETKKKGVG KVEEKQAILH EEGKMDDGLD FSRSQEEESR TARVIRKCSS LFTKFISGLE
     TLQENRRHSI FLQTVNLGEM VMCLEDLINY FAQPEDDMEH EEKQNRLRAL RNRQDLFQEE
     GVLNLILEAI DKINVISSQG FLASFLANDE SGQSWDMISG YLYQLLAAII KGNHTNCAQF
     ANSNRLNWLF SRLGSQASSE GSGMLDVLHC VLIDSPEALN MMRDEHIKVI ISLLEKHGRD
     PKVLDVLCSL CVGNGVAVRS SQNNICDFLL PGKNLLLQTG LVDHVASIRP NIFVGRVEGS
     AIYQKWYFEV TMDHIEQMTH MMPHLRIGWA NTAGYVPYPG GGEKWGGNGV GDDLYSYGFD
     GVHFWSAGRR TGVVPREVSE PYIKKGDVIG CTLDLSVPII RFTFNGEPVQ GCFTDFNLDG
     MFFPVMSCSS KLSCRFLFGG DNGRLKFSPP PGFSPLVQCL MPAQNLSLDP CFYFGNLNKN
     VLAGPWMVED DTAFVPKPVD TSTITLTSSV ETIRDKLAEN IHEMWALNKI EAGWTWGERR
     DDVYRIHPCL TSFEKLPSAE KRYDCQLAVQ TLKTILSLGY YISVDKPPAR IRPIRLPNDP
     YMQGNGYKPA PLDLSAAVLT PKMEELVDQL AENTHNLWAK ERIQQGWTYG LNEDSENLRS
     PHLVPYSKVD EAIKKANRDT ASETVRTLLI YGYNLDPPTG EANEALAAEA LRQKFAAYRT
     YRVERTYAVT SGKWYFEFEV LTAGPMRVGW ARADCNPGTM LGSDDSTWAF DGYNEEKVSG
     GATESFGKQW VPGDIVGVFL DLVDHTISFS LNGELLMDAL GGETTFADVN APEGVGFVPA
     CTIGIGQKAR VVYGQDVDSL KWFTTCGLQE GYEPFCVNMK RPVTHWYTKD QPIFENTDEI
     PDGKIDVTRI PGGADTPPCM KISHNTFETM EKANWEFLRL SLPVTCANTF ISESEKMRRW
     EEIRIRQHRL MTEVDHAAPA HFDHIMRSGF TMNDIKGLHR NYSEDAAEGD EMLRNGPRRP
     SRHATRGGLS PPGIEINGEA TSDGELNAYS DNELEGPGDD RKKRGRSPFR LFGKKRDQSK
     DKLKDRRTPE PEPRKSNLKA TQRSPAMRLS SSDLRPQPPM TPERKGMGSP QVESFGNEVY
     DADCLRLINE YFYGVRIFPG QDPTHVYVGW VTTQYHVHSK EFGQNKVRHA AIYVEDETGK
     TIEIVNRQSC YMVRADELFN EVTQDSSGKG ASQGMFVGCF VDTATGTIRF TCEGKETSHV
     FLMEPDTKLF PAIFVEATSK EILQIELGRT PTTLPLSAAV LPTGDKHINP QFPPRLKVQC
     LKPHQWARVP NTALQVHALK LSDIRGWSML CEDPVSMLAL HIPEEDRCID ILELIEIDRL
     LQFHAHTLTL YSALCYQSNY RAAHALCSHV DQKQLLYAIQ SEYMSGPLRL GFYDLLISLH
     LESHATTMEV CKNEYIIPLG SDLRDLYNDP EMCHSLRSLQ TLSVRPEMNM TEIAPTPSQS
     NMPTIVAPDS SSEPIPAIDS LYSPRFPLEV VREFVMSALQ EAVLMNQVHN RDPIGGSNEN
     LFLPLIKLID RLLLVGVITN EDVEKLLIMI DPETWDPLFQ KEGKDEHRKG LLTMKMAEGA
     KLQMCYLLHH LYDVQLRHRV ESIISFAHNY VGDLQQDQLR RYIEIKQSDL PSAVAAKKTR
     EFRCPPREQM NAILGYKNLE EEDLENASCG PDLRNRLIEF HEKLMGKVSL NALQEPEEPE
     ADKAEDGRPG AIKKLYNFIN AVKELEEDPK EPVEEEKKTP EEVFRKVLIK QIVSWAEEAQ
     IENPKLVREM FSLLVRQYDT IGELIKALNK TYVINAKTKS DVANMWVGLS QIRALLPVQM
     SQEEEELMRK RLWKLVNNHT FFQHPDLIRI LRVHENVMAV MMNTLGRRAQ AQSDAPVQTA
     EGEESAPKEK DTSHQMVVAC CRFLCYFCRT GRQNQKAMFD HFDFLLENSN ILLSRPSLRG
     STPLDVAYSS LMENTELALA LREHYLEKIA IYLSRCGLQS NSELIERGYP DLGWDPVEGE
     RYLDFLRFCV WVNGESVEEN ANLVIRLLIR RPECLGPALR GEGEGLLKAI IDANKMSERI
     SERRKLMDEA EGTIVGLNFS HPLPEGDDDE DYIDTGAAIL CFYCTLVDLL GRCAPDAAVI
     EQGKNESLRA RAILRSLVPL EDLQGVLSLK FTLTNPAVGE DRPKSDMPSG LVPGHKQSIV
     LFLERVYGIE TQELFYRLLE DAFLPDLRAA TMLDRSDGSE SDMALSMNRY IGNSILPLLI
     KHSKFYNEAE NYASLLDATL HTVYRMSKNR MLTKGQREAV SDFLVALTSA MHPAMLLKLL
     RKLTIDVSKL SEYTTVALRL LTLHYERCAK YYGTTGGGQA SQFGASSDEE KRLTMLLFSN
     IFDSLSNMDY DPELFGKALP CLIAIGCALP PDYSLSKNSD DDLYGKPTGG GPDQPHYNPQ
     PIDTTAVQLT NDLNQIVQKF SEHYHDAWAS RKLENGWTYG DQWSDSSKTH PRLKPYNTLG
     ENERERYREP VRESLKALLA LNWRIEHSEG DVPLSNRGSM RRQSKPNLEL QGDTGSPFNY
     NPHPVDMTNL TLSREMQNMA ERLAENSHDI WAKKKNEELN QCGGAIHAQL VPYDLLTDKE
     KRKDRERSQE FLKYLQYQGL KLHKPSRGQT EEPGMSTAAI ELRFAYSLLE KLISYSDRAT
     INMKLLKPSS TFSRRSSFKT CSRDIKFFSK VVLPLMEKYF SSNRNYFIAI ATATNNVGAA
     SLKEKEMVAS LFCKLASLLR HRLTAFGADV RITVRCLQVL VKSIDAKSLV KNCPEFIRTS
     MLTFFNNTAD DLGQTIVNLT DGKYDRLRGT HLKTSTSLAY VNQVILPVLT SLFDHLAACD
     YGSDLLLDEI QVASYKILSA LYTLGTDMSL TRDRKYLKTE LERHKPALGS CLGAFSSCFP
     VAFLEPHANK HNPFSLLNRI ADTSLEAQDI MTKMESCMPT LESILSEVDQ FVESEKTYQE
     AQHIIDVILP LLCSYLPFWW NQGPDNVSPQ TGNHVTMVTA DHMNHLLKNV LKMIRKNIAN
     ENAPWMTRIA TYTQQIIINS SEELLKDVFL PLAERVKKRC DSMFHKEESL RGFLKSSTDD
     TSQIEAQIQE DWQLLVRDIY SFYPLLIKYV DLQRNHWLKD NVSEAEELYN HVAEIFNVWS
     KSQYFLKEEQ NFISANEIDN MALIMPTATR RSAAISGDVP ASGGKVKKKK RSRDKKRDKD
     KEIQSSLMVA CLKRLLPVGL NLFAGKEQEL VQHCKDRYLK KMPEYEVIEF ARTQLTLPDK
     LDPADEMSWQ HYLYSKLGKK EQIVPDTIEK SDKKPENKIE DTVERIVAMA KVLYGLHMQT
     FEDAEKKKKD EEEEEGKPDP LTQLVTTFCR GAMTERSGAL QEDPLYMSYA NIVARSCGEE
     EEEGGDEEEG AGEDEGGASI HEQEMEKQKL LFHQARLANR GVAEMVLLHI SASKGLPSEM
     VMRTLELGIA VLRGGNIDIQ MGMLNHLKEK KDVGFFTSIA GLMNSCSVLD LDAFERNTKA
     EGLGVGSDGA AGEKNMHDAE FTCALFRFIQ LTCEGHNLDW QNYLRTQAGN TTTVNVVICT
     VDYLLRLQES IMDFYWHYSS KELIDPAGKA NFFKAIGVAS QVFNTLTEVI QGPCTQNQQA
     LAHSRLWDAV GGFLFLFSHM QDKLSKHSSQ VDLLKELLNL QKDMITMMLS MLEGNVVNGT
     IGKQMVDTLV ESASNVELIL KYFDMFLKLK DLTSTPSFME IDANGDGWIM PKDFREKMEQ
     QKSYTPEEIE FLLACCETNH DGKIDYIGFV DRFHEPAKEI GFNLAVLLTN LSEHMPNEPR
     LARFLETAGS VLNYFESFLG RIEIMGSSKR IERVYFEIKE ANIEQWEKPQ IKESKRAFFY
     SIVTEGGDKE KLEAFVNFCE DAIFEMTHAS GLMASDDDGA TVRRDQAFTY ISEEEEERAA
     QDPIKRTIQA IKDGLSYSMY MISPSNIKHQ ITVLQTKSFP EIIVGFFKMI FYAFYYSGFG
     VSVVIKYLVN ILMSLMRGPA QEEEEPIPEA EPSLRALPPL PLEEPPGTVQ AFGLDISKEE
     NGQYRMAPHE SPALSPSSSI EETGESSPED GANELTGEGV APGEQMTLVD LLGGEAAKRA
     AQERTEAQKA QEATLASIEA ESKKASTETK EPAAVHQIDF SKYTKKCVSY LARNFYNLKY
     VALVLAFCIN FMLLFYKVTT LGDDEDAEGS AEGLMGLGSG MGSGLGILET GSGGGEGGSG
     DGEGEEEDPL EKVHVDEDFF YMEHVLRVAA FLHSLVSLAM LIAYYHLKVP LAIFKREKEI
     ARRLEFDGLF IAEQPEDDDI KSHWDKLVIS AKTFPVNYWD KFVKKKVRQK YSETYDFDSI
     SNLLGMEKTA FTAQEANDGG GFFHFIANID WRYQIWKAGV TITDNSFLYS LWYFTFSVMG
     NFNQFFFAAH LLDVAVGFKT LRTILQSVTH NGKQLVLTVM LLTIIVYIYT VIAFNFFRKF
     YIQEDDDGEE GDRKCHDMAT CFVFHLYKGV RAGGGIGDEI GDPDGDEYEV YRIMFDITFF
     FFVIVILLAI IQGLIIDAFG ELRDQLESVK EDMESNCFIC GIGKDYFDKV PHGFDTHVAQ
     EHNLANYMFF LMHLINKPDT EYTGQETYVW NMYQQRCWDF FPVGDCFRKQ YEEELGGGSS
//
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