ID A0A182JWS9_9DIPT Unreviewed; 1025 AA.
AC A0A182JWS9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Macoilin {ECO:0008006|Google:ProtNLM};
OS Anopheles christyi.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=43041 {ECO:0000313|EnsemblMetazoa:ACHR002961-PA, ECO:0000313|Proteomes:UP000075881};
RN [1] {ECO:0000313|Proteomes:UP000075881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACHKN1017 {ECO:0000313|Proteomes:UP000075881};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles christyi ACHKN1017.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ACHR002961-PA}
RP IDENTIFICATION.
RC STRAIN=ACHKN1017 {ECO:0000313|EnsemblMetazoa:ACHR002961-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}. Nucleus membrane
CC {ECO:0000256|ARBA:ARBA00004232}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004232}. Rough endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004269}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004269}.
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DR AlphaFoldDB; A0A182JWS9; -.
DR STRING; 43041.A0A182JWS9; -.
DR EnsemblMetazoa; ACHR002961-RA; ACHR002961-PA; ACHR002961.
DR VEuPathDB; VectorBase:ACHR002961; -.
DR OrthoDB; 2882564at2759; -.
DR Proteomes; UP000075881; Unassembled WGS sequence.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030867; C:rough endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0023041; P:neuronal signal transduction; IEA:InterPro.
DR InterPro; IPR019130; Macoilin.
DR PANTHER; PTHR13289:SF6; MACOILIN; 1.
DR PANTHER; PTHR13289; PROTEIN PHOSPHATASE 1-BINDING PROTEIN BIFOCAL; 1.
DR Pfam; PF09726; Macoilin; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 206..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 491..584
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 674..701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 884..904
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..335
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..526
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..554
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 564..584
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1025 AA; 109009 MW; 961CB4E19F15E30A CRC64;
NTLLYIKFLL LWASVITADF LLEFRFEFLW PFWLLLRSIY DSYKYKGLAF SVLFVCIAVT
SDLVCLFFIP VQWLFFAAST YVWVQYVWHT DKGICLPTII LWILFVYLEA AIRWKDSRNI
PHLNLCRPFA AHCIGYPVVT LGFGFKSYVG YRIRQRKQRE VAKDNDFYMQ LLQEALPKEE
SRALEPLVDG ATGSEQLTAP KEIVPVASVS SPSSASTSAM NGGLNHSSHQ QQGSSKHRKS
LDKDSSSSSS SSNSSSNSSS MFNAGSKMNG GSGGNGSNYS YHQATTFQQN GGNNSSTSSS
SSSNSCSSNS GSATLSTKEF STTVGRGNDH NGSIHCNGGS VAKDSKDGSG QGLVVRKDND
KETPNSTSTS SAGSIGSSVS STAKHGTSQT AATNRSKSPT ESSTFSTVGS NSKTNSGKQN
GHISQFHQAE QVQSVASTEV TSTGTESKGG GGRSGRKNRL KKAAEQAQLS AIAKICATIA
LASSVTTLTT TGGATLSSGG GGDKATTITS SSYTGSVPSA SVKDNHQHNG EQVKDSGEGG
YNSNSGSGTR DNKKDPNGLS VGGTAKATPM TTGSSVQASS AGTSSPIATT VVVQKVCETC
PRLEGDLKKL RAEMSSHRQT ENELRQKYDS TTGNLKSCLQ AKQKEYDELH TRYQDLSSQR
QQERQNLQTV ERRLGEERRH RQSLEAQLNN ERKYRKQAEE KAARSECGES CKMKKQQMEM
EIDKLQHEML NAEDAKLMAE KQARNYEQEM RKFELQLRSR ESQPNTEVLI SALAAMRDKN
ETLEKNLSAE TRVKLDLFSA LGGTRREVEI LTCNLRSKEK EILDLNAKIV QLVAVMPNDA
LVLTSHGGGA GSDGSSMMRL ADAPQLLPQS LSSGHLNGIG PVGGGGSVGG GGTGGSGMHQ
SNQQQQTSPM SHMVVQNGPS FCSQLGSLGV LTSTMTTLPS SSVLAGPNSN TANNGCGVHP
SSGATVCVGL SSLGGTGSGN NGGQIVQMQN SNNGGTNGGN CPSSLDPNAT IYTPKNNGMV
GGTEA
//
