ID A0A182JXH9_9DIPT Unreviewed; 1349 AA.
AC A0A182JXH9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=RING-type domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Anopheles christyi.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=43041 {ECO:0000313|EnsemblMetazoa:ACHR003211-PA, ECO:0000313|Proteomes:UP000075881};
RN [1] {ECO:0000313|Proteomes:UP000075881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACHKN1017 {ECO:0000313|Proteomes:UP000075881};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles christyi ACHKN1017.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ACHR003211-PA}
RP IDENTIFICATION.
RC STRAIN=ACHKN1017 {ECO:0000313|EnsemblMetazoa:ACHR003211-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR STRING; 43041.A0A182JXH9; -.
DR EnsemblMetazoa; ACHR003211-RA; ACHR003211-PA; ACHR003211.
DR VEuPathDB; VectorBase:ACHR003211; -.
DR OrthoDB; 1352at2759; -.
DR Proteomes; UP000075881; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR CDD; cd16787; mRING-HC-C3HC5_CGRF1; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR025696; MTR4_beta-barrel.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR InterPro; IPR040801; Ski2_N.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF13234; MTR4_beta-barrel; 1.
DR Pfam; PF17911; Ski2_N; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 70..105
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 415..571
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 647..846
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 125..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1349 AA; 151146 MW; 00386E69D931B328 CRC64;
MTADEATTAN GGSNGGATGN GAGSGTGTTG TTVPTGTLSL AEPVACAGNN EPLLCSDSAP
RDCPVGEQLC VVCHYFPLSR ALLPCRHTCI CAVCFSKLDR CPMCRATITS YFCIRTEEYL
PANSTNEHKV NGKPKGTPAW LKEPPPIVED TEDLLRAFIL EPKIPINEPK PYFEPRHPSV
EQLYDIPQAA LSTRIVPERC PETGKVLDFI ETLLLNAGST AKNSMSLQRE PTESLDSARG
SASYFPFWPG GFDEPENVLA DLVPNPLFDT DLKSCPPGFA TGVEFEAPSR SDGSRLEDSG
KGGVIDLLSA IATDDGFDLL SDRMQTQTSD EKGRHEETKP LPEGIDDETL LAVESERGTE
GEVLKISNVI NNALQTAEWA EMLDISKPVD DFYVKIPVMA HRFPFELDIF QKQAILKLEE
HSHVFVAAHT SAGKTVVAEY AIALSKKHMT KTIYTSPIKA LSNQKYRDFK TTFQDVGLIT
GDIQIDPTAS CLIMTTEILR SMLYCGSDIT RDLEYVIFDE VHYITDSDRG YVWEEVLILL
PDHVCIVMLS ATVPNTIEFA NWVGKTKKKR VWVVSTAKRP VPLEHYLYTG FGGKSKDDSF
LIVNEQSQFV QDGYRRAKES YDAKQAKNTA RWNGPYSQRQ EQTLWVGLID HLRKKEKLPV
VSFTLSRNRC DNNAEALVSC DLTTAREKYA ITSFFQQCLQ RLVPADRVLP QVQQIQSCLE
RGIGIHHSGI LPILKEIVEM LFARGLVKIL FATETFAMGV NMPARTVIFD STRKFDGQAF
RPLQPSEYTQ MAGRAGRRGL DKTGTVIILC KQILPTDGEL KTMILGKPVR LESQFRLTYA
MMLYLLRVEL VSVENMMLHS FREFDKRQQM PQSKLELSKV QEKVSDLSKL SDHLQPLCEF
YESANDYLLL RNELLPKQLC QPKAINELKV GRVVVVTDEH HYNKLGILLS FSVQSHKDLK
LVVLVLDHHG DGKAQHAPSD TLNRGTLWHQ MLSLALPYQT FLPEGVGGHA VLTLAPVNLV
ELTKHSIKCD ANSIIRSWQN RLIPRFRDAP PSQTTIEAIA ALAELNASVV QTGSVSGTLE
LVRFQRDLTN LELTEQLKVA QDRLNRWLPY TNIADFEHEF ALVYDRKQLE RKLDELKYQA
SYESLSLYPD YCRKLQVLQE LKYIDDMQQV AMKGRVACEM GQNELMITEL VMRNILTVLQ
PAEIAALLSS LVFQAKSDVK PKLTETLQKG EAQFREVEND IRLVERQYGV TDVCKKEELN
FALTEVVYEW ARNKPFAEIM LLTDIKEGII VRCIQQLNET LCNVKEAARI IGDPVLHSKM
EEASNAIKRD IVFAASLYTS NTPIVIGEV
//
