ID A0A182K388_9DIPT Unreviewed; 1511 AA.
AC A0A182K388;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=FERM domain-containing protein {ECO:0000259|PROSITE:PS50057};
OS Anopheles christyi.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=43041 {ECO:0000313|EnsemblMetazoa:ACHR005223-PA, ECO:0000313|Proteomes:UP000075881};
RN [1] {ECO:0000313|Proteomes:UP000075881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACHKN1017 {ECO:0000313|Proteomes:UP000075881};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles christyi ACHKN1017.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ACHR005223-PA}
RP IDENTIFICATION.
RC STRAIN=ACHKN1017 {ECO:0000313|EnsemblMetazoa:ACHR005223-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR STRING; 43041.A0A182K388; -.
DR EnsemblMetazoa; ACHR005223-RA; ACHR005223-PA; ACHR005223.
DR VEuPathDB; VectorBase:ACHR005223; -.
DR OrthoDB; 3795301at2759; -.
DR Proteomes; UP000075881; Unassembled WGS sequence.
DR GO; GO:0071944; C:cell periphery; IEA:UniProt.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0009887; P:animal organ morphogenesis; IEA:UniProt.
DR GO; GO:0030182; P:neuron differentiation; IEA:UniProt.
DR CDD; cd13185; FERM_C_FRMD1_FRMD6; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR041781; FRMD6-FERM_C.
DR InterPro; IPR047145; FRMD6-like.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR13429; FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY; 1.
DR PANTHER; PTHR13429:SF13; PROTEIN EXPANDED; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR PRINTS; PR01217; PRICHEXTENSN.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
FT DOMAIN 1..395
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 107..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 528..565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 585..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 677..701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 739..758
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 803..827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 845..895
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1032..1051
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1240..1271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1286..1328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1394..1511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..250
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 677..700
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 848..864
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1246..1271
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1301..1321
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1420..1434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1441..1456
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1478..1511
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1511 AA; 160188 MW; 27277300CAA308CB CRC64;
MAAGGFGIKY GEYLFADPES KLSKYGPKSW RSSHTHGLDA NGKPLLELHF RVQFYIESPL
MLRDEVSRHN YYLQLKYNAV NRDLPKEYSE QSLLLLGGLS LQADLGDSAP EDAGTLPTTP
SITTSTSTAT VPCSSSGTTA TITNTGGALS SGNSVSSSNS TSSSSNSSSS TSSNSSATSS
SNSSTTSASS PNPSASGALS VSSTSTATSS ACTTSGPPLL GTGVVGQSAS SDGGANNAGS
SSTSSGSPSL EYFRPDEYLN PALRSAWGIS AVTTCHRENR GLSRADAETH FIREACNLNE
AINAHVFRMK QSKNETGLGT VALSIYAKGI RIATDGSSTA TTFQWPHIGK LSFDRKKFEI
RSGDSKITLY STNDDKNKMI LALCRETHQF SMKIAPRLTE AIKREEEESS CIHGYPYLCS
RALNLPYKSK SDQRISVISS TSSNTTSGIV SDRVHSEDEL EIMINTPPTA TLAAPSTESL
ALAHLLDCPS VSRQTSSVGQ VSLKDLEGTF AALSVGRTAN VVNAGSIITN SNSASSDSGS
VEGKPDRPGK DCDSSPSSQH NIGSQCSSTC STVVVATDCL SLPQSSTATS TTTISNGGGT
MVQSTISPDR RQTSTCSSLV LGFSHTAQNS TLSVATSTCL DHDINEEEEE THSGVYTIAH
VPPTETSGVY TMNSSELTGQ SSEIAESESH ESSHYGSFQP CQSEMADPLE PVDSVDGDYH
RPRLDSGLNS EFRMRSDSNV SAAGSFRGDG SDPTDNKHSL LSAEELTDLI VGRGTYPSRK
TVSHTLDSDC DYVTLPLPLE GESYLQGSED TAPTEDEYDD EVLPPAPPKR IDSNMAAVVR
PPQLPQPVEA VGGGPPPPPP PYNAHHETTG LRGPDIRSHA APDPEAPAIP LRDPPPYPQK
PIAMRKSPVL PPALPITPVL TAAPVTEEVP ARFITTRPQI NILKAHASVV GETPKPSYAA
PTVNNIGNLA QATPPPPPPP VPSSAVGIAG YNLHPNHKAI TSPPPPYPEM PKPPPHRTTA
CVLLPVIKPR QYHPPPPPTI PRQPPPPPPP HSLATVYTSQ LARSQIELYQ QQLYSDVDYV
IYPIQDPSIS QQEYLDAKQG SILAAMAQSP PPPPYLAYHT VRAHNRSWDA CKNHAIYRST
PYLSMALSSN SRYASTQNLS DTYVQLPGAY SPLYSPSVAS LCSSYEPPPP PPLRPRPMVT
AKQSTACLQP NGGHMSMASA GPSPALFARS RSDDNILNSV ESTPKIRRHP PPPPPPPYES
KKAIRKPPLP LPLPPMPMEK IIQKPPIAVP SPSHQPPAMA AFNPERPPEV PAKPTPPKPS
GPSAKLQAQI KKQYPDFDLS TVASLTDQPA NDHTSIDIKT LREKSKHLDL PLISALMHDR
SLLKQTRAFV MPKHPKANGS MQKGGAGGTG VVPGGSPTIN GEALNGNGGS PPGNNPSPKC
KYPVSGLSTT QLAKPRKTSA SHRHPNDKLP PLPGQTGPGQ TGPTAEGNNY VMDPTPTPIK
QKSFSSSQPS A
//
