ID A0A182K3W2_9DIPT Unreviewed; 1764 AA.
AC A0A182K3W2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=PDZ domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Anopheles christyi.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=43041 {ECO:0000313|EnsemblMetazoa:ACHR005447-PA, ECO:0000313|Proteomes:UP000075881};
RN [1] {ECO:0000313|Proteomes:UP000075881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACHKN1017 {ECO:0000313|Proteomes:UP000075881};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles christyi ACHKN1017.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ACHR005447-PA}
RP IDENTIFICATION.
RC STRAIN=ACHKN1017 {ECO:0000313|EnsemblMetazoa:ACHR005447-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR STRING; 43041.A0A182K3W2; -.
DR EnsemblMetazoa; ACHR005447-RA; ACHR005447-PA; ACHR005447.
DR VEuPathDB; VectorBase:ACHR005447; -.
DR OrthoDB; 2913694at2759; -.
DR Proteomes; UP000075881; Unassembled WGS sequence.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR47644; AGAP008221-PA; 1.
DR PANTHER; PTHR47644:SF1; SEA DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00169; PH; 2.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00233; PH; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50003; PH_DOMAIN; 2.
PE 4: Predicted;
FT DOMAIN 1484..1561
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1574..1672
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 1677..1764
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 64..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..858
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 932..953
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 970..1186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1217..1240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1341..1381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1424..1447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..489
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..551
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 589..603
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 634..653
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 799..820
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 821..851
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..953
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 978..993
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 994..1013
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1031..1055
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1072..1097
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1161..1186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1341..1371
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1764 AA; 194714 MW; 4172942F90945108 CRC64;
MVVKMVSQGA QTNGGLNGGG RKLTKSLSEA GDRIQENGID PNTIQPVETG TSASVAFDHE
LLHRTQSEEP PKSPYTITSP PASHVGPHFE LPSSRTSSQL SHSDGTHLTH SRNHSQDSAT
SYRSTDGSRT SYETASYPYD AYDSIVLPRR ASHSQEPTFQ FLRKQDLEQV HHHHQQQQQQ
HQQQQHHQQQ QQQQHQSQYT HGYENGYVPF ETHSLPRRTC IHHKPEEFHT HTLPRRDHGH
GHHHHEIVYR DQSHPALPAP EHLILSNGSV NQDVRSFDSM PSATNLNRRM SAHAIVLPPE
KQHQQHSTGL PLVQGLHQQQ QQQVQQQQQQ QQRRASYAFV TADTQALAKR NSIPHQQIQK
VQPIMQAQFA TPVKTQAFQP LVKPQPPILP SHYTSQTAPP SCPVTPPNIQ PLDMQDDTKS
SSEGSCSTCE SESEPELDGP SEEREIFIDF KPRVSPIPSP GAVKKKKLQK TQSEGELLHA
ERRKASVADD GDGGSSTVPT GSDDEGRSTM REHTVPPKLP KQDYRDASES SVPDDEPQVI
DRRKESFRKR SVSLDQPTSC EQEDDDDQRN GSVAQQRNGD GGRTHPHGAQ RMSSRSRSIS
AAIGSRHLSA PPSPQKEDHS ASTGRLHREV SPFHSSDSLA NDATRDTSDG NWNESQATIM
TTSLTDNGKL TPSARRKNLL LQHQQRSSMD TDALDMEDIA DQPLPPLPVT VASTALQTNT
VSTPSCHGHQ QPNGTAIQPT VAGVGIVKPT TPSIAVIPSP SMEREERDLQ WQKSATLRRP
SRPLSPTKRA ARNEQQLQQK QQKMHKIEPL IHRSSDTSDR TGKSDPSPTS SMPSGSGGPT
TPQQPSPSST KLPHHHPIGV TTPVAARFTK GSPGNGVDLL KDHPVFSQDP VISVPSGAGG
GAGSEGSTTE DYVTCTDNSK RGASGAKGTY KTIHATRPTK QVTATTQDGS SFESASSIYS
LARVDAVCEE TPPIEEKSVS PQIPPPPIPK PSPTHSVSSS SSDSFSVSKK SSPSRVALPK
AIAGKAKPSK PQSLSDDERS EKRYSSSHDE KEPTSKGPYA GSATGTIARS ARRGRDWNEE
ERRRKKSTFK LEFDKDSIKT YTTPMLRQPS PGFKKLSPED KSALNVLDGA SPSSKQKRFR
PKTRKSPRAR SAVPEETNAG GVVGSTGTLP RRSKTPLVRS PEKPTTLVTV ATTTAVVMAT
PQPTIVAPVT NLSPSQYYSQ IRSPPSAGSP RKQKISPEKR LQAISTESLR SVSPGSDSVF
YSEADALSHC EQQVHCSHCG KEVEVANIPG ESEESILTLD STDNDRPDIV QPPEGFADSP
DCTKTPHHTR LYKKMDKRFR SEDRHVDRRH FKSRQEYRAK SEERGKEEVE PNNLRPAGSS
PCVAPAGQAY IDTTSEPEQG VYHGNYKAGL WICIADRDVW RRNELPDGSF ERPKDATLER
RGSTDSERDF RKKYQAITHR LVHRKSCVEM YRRQNSNSFD TDKTVVVCRK SGEFGFRIHG
SKPVVVSAIE PDTPAETSGL EVGDIVLSVN GISVIDKSHS EVVKIAHAGS DTLELEVART
IGMLSPLDDG STHPSIYTGF LWRYCSSGGK WVRRWFSLRP DHCLYYYKSD SDNQPIGAIM
LTNHTIERIP LEPITRPNSF AIDTEEGTKV QLSADSEEAA SRWIAIISHA AQQCDPWLEN
SGPLTKLGSK WRSWTKRYCV LKDAVLYFYH DGQSKSAFGM ACLQGYRVQP SSAGGKKYAF
EIVPPELSLR HYYFHTETEM DKKR
//
