ID A0A182K8B5_9DIPT Unreviewed; 2158 AA.
AC A0A182K8B5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Cell adhesion molecule {ECO:0008006|Google:ProtNLM};
OS Anopheles christyi.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=43041 {ECO:0000313|EnsemblMetazoa:ACHR007000-PA, ECO:0000313|Proteomes:UP000075881};
RN [1] {ECO:0000313|Proteomes:UP000075881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACHKN1017 {ECO:0000313|Proteomes:UP000075881};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles christyi ACHKN1017.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ACHR007000-PA}
RP IDENTIFICATION.
RC STRAIN=ACHKN1017 {ECO:0000313|EnsemblMetazoa:ACHR007000-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR STRING; 43041.A0A182K8B5; -.
DR EnsemblMetazoa; ACHR007000-RA; ACHR007000-PA; ACHR007000.
DR VEuPathDB; VectorBase:ACHR007000; -.
DR OrthoDB; 4136946at2759; -.
DR Proteomes; UP000075881; Unassembled WGS sequence.
DR CDD; cd00096; Ig; 4.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 15.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR45080; CONTACTIN 5; 1.
DR PANTHER; PTHR45080:SF8; WRAPPER_REGA-1_KLINGON HOMOLOG; 1.
DR Pfam; PF07679; I-set; 7.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF00090; TSP_1; 1.
DR Pfam; PF13768; VWA_3; 1.
DR SMART; SM00409; IG; 15.
DR SMART; SM00408; IGc2; 14.
DR SMART; SM00209; TSP1; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 14.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50835; IG_LIKE; 14.
DR PROSITE; PS50092; TSP1; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..2158
FT /note="Cell adhesion molecule"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008125124"
FT DOMAIN 294..504
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 684..772
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 777..854
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 866..952
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 958..1060
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1065..1159
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1166..1244
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1249..1334
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1339..1416
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1524..1621
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1626..1707
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1709..1827
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1832..1899
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1920..2015
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2022..2112
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 50..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 119..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2158 AA; 238794 MW; 849A311D277E6AAB CRC64;
MKLAMQKDAF ILAILLGCCA IAAGKTRHEL DNDELWDRLL KRKLHETKTN VHDEEGRVES
VPEPAALRGD QSPLPDDDEE LDGGLISDIS YQQHQHDANS ELIDSAILIP DERDQLLTLD
GSAPSKVGEF PPVDTADSGW ASDDEAFDPD LVNSNDDVGE GSGAGDSLPQ ADDPLLFDKE
IVSILRKRPE SREMMDLLGL GAPVANDTSA NDPATIKEQL RTMLSLPMDK RKYYQPLPGI
AEEEAELRHR AEPASLLADG RNPPRLSNVL LPELTQALAT RRESLLPPKE GQRSLVIVFD
ATGSMLDDLQ QLRDAARLII AEITQRDSNP IYNYVFVPYR DPHVGPRLVT RNVDELLNAL
DSLQIIGGGD CPEAALEAIA SAIEAAMPNS FVYVFTDATA KDFRLDQRVL QLVQQKQTPI
TFLLTGFCDG KGTPGYQVMD NIAAASNGQV FDLRKDQIEE VLLAIRTTMD VDHVPLKAID
SPQASQHEID LNVDSTLREF SVSVAGVKPT IEILDPQSTP YNGTRDVLNL DNIRVVNVAD
PVPGRWNIKA TSNSSHSVRL SGLSEVQFRF GFSLLEPQDT ISLSHQPVLN KANYLAIEPT
DPQLINRLDS VTIASHNVGA PGGTKFNFTL PLKLVPGTGA LYRTDAFDVP RQQFKLTLNG
QNANGQTLQR LLSTAMQAVE QTPPEVSVGF APVLDLLEGD TFMLDCRIQS PFPVMAAWVQ
GDRKQMVERK FEQSNILSLL LSNVSIADAA NYTCYAKNNI GEDMKTVLVR VTSLQKPTMR
LLPKHTLAVE GEPFIALRCF LEHHTDGTTE IHWTHNWKPL TIASGRSYLE LTEIDKQHAG
NYTCYADING QRVSSEPSTV IVEYGPKVSA PSVALLREYG TEVALECAIE SMPLPDYQWY
FETLDEAGDP QVYESAPNNR TIRFVMTPEQ EGLYVCEAKN GYGFAKQTFV VEGAANAPPV
IQKPTETTIY VASGGMITLD CVCELCQPLN EYIWTSQQGT FESSPEETID NVRVVLDNDQ
SRNAVHYRLT IDGFRPHNVA SYTCIFSNRH GADAMILQLR MMVRPEVDFM LLDGVTIPAG
THHYRERGQA HSLSCEMVGL PEPTVHWLQN GQPITENENF QFENDNKTVL FRKPFDWTLQ
GNYECIASNP LGSVSSNVVL LLAEAPVALQ SPARKLVAKV GETVTLDCTI EGMPHPTIRW
MPEGSFSDPF QTKQTLQVTY ETAGLYRCTG TNEYGTAEQT FTLETYGPPE VKGPLDLSLQ
FATNQSVLLD CSGWGIPEPT VHWNFNDTRL VPAPNMELSG EGLHISNIAY AQTGVYSCVL
ENEHGSLQKI HYVTVRDAPK VTSTVPPHLT LLPNETTQFK CSGTGSPPPR AVWLFNGTTL
LQEQTLHLAH ANASTGTYTC QLESSEGTDR QNMFVSVLRP PQRLSGMNYT DHLAPLKIRT
DDPLVLTCPF NNFNSLLWQL NERNLEEHFD LTDVRLKENL LIIDRIRLRH QGTYTCVVAN
RAGTERQSFV VGVLTPPTIH RTHPDVLSDE YGGTVEDWDS TWNRDGAVEV NLLSGETLQL
LCQASGSPEP TVQWNRGADT AQIVSQTANL TIPSVALHHS DLYTCVAENE LGKSTQVYRL
DVMTSPLFYD EPIQSIEVYV GEDLQLDCEM QSNPPASYQW LKEDVALEEF DTVLEFFNIQ
PQDTGTYHCE AENIFGHNKK SFKVLVYQPA EITVFASNQT LLAGNSIELD CEAIGNPIPI
LSIIHRGEVL ASTADLDAAA MEIDRQYRVK NNFYKSLQMY SFHAVRTAPF EVRFALRQPH
ATLLDRGKYL CMAQNAIGFD ERLARLDVAV APYVQVDKLK SFDTTIRLLE GLPLFLYCPI
DGTPKPAIGW YRNGIRLKHT ASTLFLPAVQ LRDAGSYLCY GENPVGKTEL LFELEVLVPP
SIINSVLYGE AFLSADQPDQ EEVSLLAGET VTLDCSSLGH PVPVVHWMKV DYLDERENVL
LPTQEPILEL HDVRATVTYS CFVNNTAGSA QKLFHLVVQA APSWKAGPGY EYEQRVSLHH
SLDLTCETNG SPDASVTWLK DGVQLGKHDV GLFFGANGQT LRLLAAKLTD AGSYQCVASN
ALGQISREFH VTIDVPVSWS PWGGWSACSA TCGSGTQFRS RICLLVNGSP AHGERFNC
//
