ID A0A182K8H7_9DIPT Unreviewed; 439 AA.
AC A0A182K8H7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Translation initiation factor eIF2B subunit gamma {ECO:0000256|ARBA:ARBA00044196};
DE AltName: Full=eIF2B GDP-GTP exchange factor subunit gamma {ECO:0000256|ARBA:ARBA00044229};
OS Anopheles christyi.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=43041 {ECO:0000313|EnsemblMetazoa:ACHR007062-PA, ECO:0000313|Proteomes:UP000075881};
RN [1] {ECO:0000313|Proteomes:UP000075881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACHKN1017 {ECO:0000313|Proteomes:UP000075881};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles christyi ACHKN1017.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ACHR007062-PA}
RP IDENTIFICATION.
RC STRAIN=ACHKN1017 {ECO:0000313|EnsemblMetazoa:ACHR007062-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the eIF-2B gamma/epsilon subunits family.
CC {ECO:0000256|ARBA:ARBA00007878}.
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DR AlphaFoldDB; A0A182K8H7; -.
DR STRING; 43041.A0A182K8H7; -.
DR EnsemblMetazoa; ACHR007062-RA; ACHR007062-PA; ACHR007062.
DR VEuPathDB; VectorBase:ACHR007062; -.
DR OrthoDB; 161736at2759; -.
DR Proteomes; UP000075881; Unassembled WGS sequence.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd04198; eIF-2B_gamma_N; 1.
DR CDD; cd04652; LbH_eIF2B_gamma_C; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR45989; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA; 1.
DR PANTHER; PTHR45989:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 8..137
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 439 AA; 48735 MW; 432A1FA7C844E156 CRC64;
MGQLEFQAIV LAAGKGTRLP EILEGRPKCL LPIGPFPMIW YPLQLLQRHG FTEVIVVVQE
SQKSEIQQRL ERLQLKLKLD YYSIPTDSEC GTADSLRLVS DKIKSDVVVL SCDSIIEVNL
YPLLSKFREK DASIQLLLLE SGKDLDVVMP GPKSKYKAEK DIIGYDKTTS KVLFMASASD
FEETVKLSGH LLRENPEMTI SSHLLDAHVY IMKKWVVEYL AVSELLSAVK GELLPHIIKK
QLLQPPAVPE NDGASEYTAI PKVDDIFQFA VYTEMDKMID KASVFNKEEK NTSHPIRCYA
YFADPKAFGL RIFEIFPGLT GFTERELVSQ TSSIKSTQIT KCAVGDMTTI SEKTSLNQNV
IANGCTVQPK TRINNSVLMD GVTVEETVVI DNCIVGEKAV IKSGSVLKNC IIGPHFVVAA
GTKKESVYLS NADGFMTID
//
