ID   A0A182KCI6_9DIPT        Unreviewed;       599 AA.
AC   A0A182KCI6;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Peptidase S1 domain-containing protein {ECO:0000259|PROSITE:PS50240};
OS   Anopheles christyi.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=43041 {ECO:0000313|EnsemblMetazoa:ACHR008473-PA, ECO:0000313|Proteomes:UP000075881};
RN   [1] {ECO:0000313|Proteomes:UP000075881}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ACHKN1017 {ECO:0000313|Proteomes:UP000075881};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles christyi ACHKN1017.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:ACHR008473-PA}
RP   IDENTIFICATION.
RC   STRAIN=ACHKN1017 {ECO:0000313|EnsemblMetazoa:ACHR008473-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase S1 family. CLIP subfamily.
CC       {ECO:0000256|ARBA:ARBA00024195}.
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DR   AlphaFoldDB; A0A182KCI6; -.
DR   STRING; 43041.A0A182KCI6; -.
DR   EnsemblMetazoa; ACHR008473-RA; ACHR008473-PA; ACHR008473.
DR   VEuPathDB; VectorBase:ACHR008473; -.
DR   OrthoDB; 3448513at2759; -.
DR   Proteomes; UP000075881; Unassembled WGS sequence.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00190; Tryp_SPc; 1.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 4.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR001314; Peptidase_S1A.
DR   InterPro; IPR001254; Trypsin_dom.
DR   InterPro; IPR018114; TRYPSIN_HIS.
DR   PANTHER; PTHR24260; -; 1.
DR   PANTHER; PTHR24260:SF154; GH18608P-RELATED; 1.
DR   Pfam; PF00089; Trypsin; 2.
DR   PRINTS; PR00722; CHYMOTRYPSIN.
DR   SMART; SM00020; Tryp_SPc; 2.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 2.
DR   PROSITE; PS50240; TRYPSIN_DOM; 2.
DR   PROSITE; PS00134; TRYPSIN_HIS; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..599
FT                   /note="Peptidase S1 domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5008125352"
FT   DOMAIN          47..294
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000259|PROSITE:PS50240"
FT   DOMAIN          326..582
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000259|PROSITE:PS50240"
SQ   SEQUENCE   599 AA;  66971 MW;  244A572AA2F1DA7C CRC64;
     MVSIERGFLA LIVALICCAF GEAQETIAQD TDLLECGERK VKTVYLVQHG TETKEGHWPW
     HTAIYHWEKT KFEYVCGGSI VDRNTILTAA HCLFTSRGKI KLDQLSVQVG RNQLSEASAR
     SQEHQAEQLI IHPGFNPNSV ADDIALIRLA TDITMTRYVQ PVCLWSLEPN LDLIVGRNGT
     VVGFGLTEHD RVSDYLRQAA IGVVDSWTCI ESDREVYGAT LTATMFCAGG TAGVSVCNGD
     SGGGMFFEIG ENWYVRGIVS FMPLRENIGL CDGTKYTVFT DVAKYRGWIG QFINPTLASV
     RPDPLLVDNS PKLRLLNFNT CGLSPYAAGV NDSFFAFPWI GLVEVTVRGQ GGRTMALCHV
     TLISEWYAVG PAHCFSNDGM ERTLRFGDYN KTTDKDCIER NGTQICAPPV QMLPIERIFI
     RPDYNRVAIT DDLALIELRR PANISQPNVR PICLPVTVDL RSYKPSTYTL AGFPAQGDRI
     VTSHPSYLNS VNCQERYNAV NFPLRKSHTQ ICALAELSTN RTEPCERMLS GAVLQTVQQF
     GRKARYFLQG VLSFGARDCD PTVPEIYTNV PIYLDWILYN MREFRRAEQD TREQLIFTS
//