ID A0A182KE58_9DIPT Unreviewed; 560 AA.
AC A0A182KE58;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Sulfatase N-terminal domain-containing protein {ECO:0000259|Pfam:PF00884};
OS Anopheles christyi.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=43041 {ECO:0000313|EnsemblMetazoa:ACHR009045-PA, ECO:0000313|Proteomes:UP000075881};
RN [1] {ECO:0000313|Proteomes:UP000075881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACHKN1017 {ECO:0000313|Proteomes:UP000075881};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles christyi ACHKN1017.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ACHR009045-PA}
RP IDENTIFICATION.
RC STRAIN=ACHKN1017 {ECO:0000313|EnsemblMetazoa:ACHR009045-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
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DR AlphaFoldDB; A0A182KE58; -.
DR STRING; 43041.A0A182KE58; -.
DR EnsemblMetazoa; ACHR009045-RA; ACHR009045-PA; ACHR009045.
DR VEuPathDB; VectorBase:ACHR009045; -.
DR OrthoDB; 2913702at2759; -.
DR Proteomes; UP000075881; Unassembled WGS sequence.
DR GO; GO:0008484; F:sulfuric ester hydrolase activity; IEA:UniProt.
DR CDD; cd16029; 4-S; 1.
DR Gene3D; 3.30.1120.10; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR047115; ARSB.
DR InterPro; IPR024607; Sulfatase_CS.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR10342; ARYLSULFATASE; 1.
DR PANTHER; PTHR10342:SF273; RE14504P; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR PROSITE; PS00523; SULFATASE_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..560
FT /note="Sulfatase N-terminal domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008125554"
FT DOMAIN 33..354
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
SQ SEQUENCE 560 AA; 62671 MW; 2489F3D7E9A10823 CRC64;
MAVRDGFWWM MMRFAIGLLP LLHVAAEEDS VRPNIIFILA DDLGWNDVGF HGSAQIPTPN
LDALAYSGII LNRYYVNPIC TPSRSALMTG KYPIHTGMQH TVLYAMEPRG LPLSEKLLPQ
YLKDLGYSNH IVGKWHLGHY QLRYTPLQRG FDSHTGFWTG HHHMNDHTAV EHGHWGLDMR
RGYDVAYDLH GKYTTHVIGS EAINVVHSHN KSSPLFLYVA HAAVHSANPY DFLPAPDETI
ADLGQIDNYR RRKFAAMMVE LDRTVGSLVD ALHARDMLEN TIIVFSSDNG GPADGFNDNA
ASNWPLRGVK NTLWEGGVRA AGFIWSPLLR NVSRVSHQMV QVCDWLPTLY EAAGGNVSAL
PTDLDGISVW HELSSGVPTR RIEILHNIDD IWGTSALTVG NWKLVKGSHY NRTWDGWYGP
AGIRNEKAYS LEMVANSPAG HVMDQLALLP CPERITQLRR EATVSCGSGV HMANECNPLA
SPCLYDVESD PCEYNNLADE HVHILQSLLA RLADYNSTAV SPSNLEDDPR GEPQHWNYTW
HNFGDEPEPK VFLNGNVDKY
//
