ID A0A182LWF6_9DIPT Unreviewed; 699 AA.
AC A0A182LWF6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Cytohesin-1 {ECO:0008006|Google:ProtNLM};
OS Anopheles culicifacies.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles; culicifacies species complex.
OX NCBI_TaxID=139723 {ECO:0000313|EnsemblMetazoa:ACUA003586-PA, ECO:0000313|Proteomes:UP000075883};
RN [1] {ECO:0000313|Proteomes:UP000075883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A-37 {ECO:0000313|Proteomes:UP000075883};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles culicifacies species A.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ACUA003586-PA}
RP IDENTIFICATION.
RC STRAIN=A-37 {ECO:0000313|EnsemblMetazoa:ACUA003586-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AXCM01002576; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A182LWF6; -.
DR STRING; 139723.A0A182LWF6; -.
DR EnsemblMetazoa; ACUA003586-RA; ACUA003586-PA; ACUA003586.
DR VEuPathDB; VectorBase:ACUA003586; -.
DR OrthoDB; 204547at2759; -.
DR Proteomes; UP000075883; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd01252; PH_GRP1-like; 1.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR10663:SF406; MIP16918P; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF01369; Sec7; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
FT DOMAIN 360..547
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT DOMAIN 565..680
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 223..253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 348..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 699 AA; 79061 MW; 8A8CAF334A8C36A4 CRC64;
MFSSMPPSAT GGSGTDVKKG PSNWFWSLRR QPKPKKVNLE PDKPLQKSCV DLPSATTNGG
PTLFGNSRLD EVVSTSSSSI ERPTFGCTCE YVQVFEPPET TGSISTTATV TKTVSRHRND
ALLESASSDS NLALSSLASP IEGAAADVQP FATNSLRRRK EQVVYGAKTV TTVTKTTVLN
RQRTYRVGLI FSDNGELLNS NHDLRQLVEE SKRNFLNALG NAGRVEHSPS IPPPPRLSST
EQVKEPNNNE QQRLKESANA ELQQFSILDD SNFDFIDDSA DLFNRNYPHQ PPASSAEPRP
ALLASPAVSL PITKVLRMCN NCKNKSNLVY QRSCSQPNRK QINDELNEVE SEMKSHESKE
ENKHSNKDKQ MALGRKKFNM DPKKGIEFLY ENQLLRTDPQ DVAQFLYKGE GLNKTAIGDY
LGEKNDFNEQ VLKAFVELHD FTNLILVQAL RQFLWSFRLP GEAQKIDRMM ECFAQRYCQL
NPDIFTNTDT CYVLSFAIIM LNTSLHNPSV KEKPTVEQFI SMNRGINNGG DLPRELLESL
YESIRAEPFK IPQDDGNDLM HTFFNPDKEG WLWKQGGRYK SWKRRWFILN DNCLYYFEYT
TDKEPRGIIP LENIAVREVT DRSKPHCFEL HASGGADIIK ACKTDSEGKV VEGKHTVYRM
SAATEEEQQE WINRLNQSIS HNPFHDILVQ RKKKALAKS
//
