ID   A0A182LWI5_9DIPT        Unreviewed;       372 AA.
AC   A0A182LWI5;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=Battenin {ECO:0000256|RuleBase:RU361113};
OS   Anopheles culicifacies.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles; culicifacies species complex.
OX   NCBI_TaxID=139723 {ECO:0000313|EnsemblMetazoa:ACUA003633-PA, ECO:0000313|Proteomes:UP000075883};
RN   [1] {ECO:0000313|Proteomes:UP000075883}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A-37 {ECO:0000313|Proteomes:UP000075883};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles culicifacies species A.";
RL   Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:ACUA003633-PA}
RP   IDENTIFICATION.
RC   STRAIN=A-37 {ECO:0000313|EnsemblMetazoa:ACUA003633-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Lysosome membrane
CC       {ECO:0000256|RuleBase:RU361113}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU361113}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the battenin family.
CC       {ECO:0000256|ARBA:ARBA00007467, ECO:0000256|RuleBase:RU361113}.
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DR   EMBL; AXCM01003964; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A182LWI5; -.
DR   STRING; 139723.A0A182LWI5; -.
DR   EnsemblMetazoa; ACUA003633-RA; ACUA003633-PA; ACUA003633.
DR   VEuPathDB; VectorBase:ACUA003633; -.
DR   OrthoDB; 2912995at2759; -.
DR   Proteomes; UP000075883; Unassembled WGS sequence.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR003492; Battenin_disease_Cln3.
DR   InterPro; IPR018460; Battenin_disease_Cln3_subgr.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR10981; BATTENIN; 1.
DR   PANTHER; PTHR10981:SF0; BATTENIN; 1.
DR   Pfam; PF02487; CLN3; 1.
DR   PIRSF; PIRSF015974; CLN3_BTN1; 1.
DR   PRINTS; PR01315; BATTENIN.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE   3: Inferred from homology;
KW   Lysosome {ECO:0000256|RuleBase:RU361113};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361113};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU361113};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU361113}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        29..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361113"
FT   TRANSMEM        60..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361113"
FT   TRANSMEM        83..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361113"
FT   TRANSMEM        119..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361113"
FT   TRANSMEM        145..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361113"
FT   TRANSMEM        205..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361113"
FT   TRANSMEM        247..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361113"
FT   TRANSMEM        272..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361113"
FT   TRANSMEM        299..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361113"
FT   TRANSMEM        334..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361113"
SQ   SEQUENCE   372 AA;  41394 MW;  9F38B17D054D231E CRC64;
     MQNDYGVANT TARADDVTFG YEKRPCNKLS TGAILLADIL PALAVKSIAS FLPLAKHIRI
     FLCVAAAAAG FLLTAFATVE WVLFVGVIAT SFSSGLGEAT FLAYATYFNK NVISTWSSGT
     GGAGIAGSLS YTGLTGLGLT PKTTILIMLV VPALEAAAFW LLLRHKDTTK PAELEEAKEK
     AEEVDFNTLP EEERPLENWN QRIRYIPSLF IFMIPLILVY LLEYYINQGL FELVYFPGIW
     LSQSEQYRWY QVIYQIGVFI SRSSVNLIQF RHVWIMAVFQ FLNVVYFTFE AVYYFTPSIW
     IIFVLILWEG LLGGGGYVNT FYRIQTDVPA ARREYAMMVT SISDSVGIAL AGVAAIPSHN
     AICDLPVPDR LL
//