ID A0A182LZG5_9DIPT Unreviewed; 946 AA.
AC A0A182LZG5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:ACUA005694-PA};
OS Anopheles culicifacies.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles; culicifacies species complex.
OX NCBI_TaxID=139723 {ECO:0000313|EnsemblMetazoa:ACUA005694-PA, ECO:0000313|Proteomes:UP000075883};
RN [1] {ECO:0000313|Proteomes:UP000075883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A-37 {ECO:0000313|Proteomes:UP000075883};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles culicifacies species A.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ACUA005694-PA}
RP IDENTIFICATION.
RC STRAIN=A-37 {ECO:0000313|EnsemblMetazoa:ACUA005694-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AXCM01004465; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A182LZG5; -.
DR STRING; 139723.A0A182LZG5; -.
DR EnsemblMetazoa; ACUA005694-RA; ACUA005694-PA; ACUA005694.
DR VEuPathDB; VectorBase:ACUA005694; -.
DR OrthoDB; 1596510at2759; -.
DR Proteomes; UP000075883; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR039241; Rrp9-like.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19865; U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2; 1.
DR PANTHER; PTHR19865:SF0; U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2; 1.
DR Pfam; PF07690; MFS_1; 1.
DR Pfam; PF00400; WD40; 3.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT TRANSMEM 71..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 483..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 718..759
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 760..801
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 850..891
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 514..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..559
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 946 AA; 103837 MW; E1462BDB08D84D5B CRC64;
MRSDMRRPSL SGRTSDEDTP LLAAPSLTSM AASTSTSPTA ATATAATSSS CSSSGARVSG
KSDRYCTFEP ILVLLCFGLS VSGVVLADQI IYQSCVVTLG YDRGLCAQLG TKSNSTDVAQ
LETIVQPYAA RITMMNTILM SVLPALCALF MGPWSDKFGR KPAMIVPSVG FIMTYVMIGI
LSLLSKHFLV DPWCYVVAHI PAAVLGGSTV LMAAIFSYLT DTTTEHNRTV RIGILQACTM
LGAFVGLLSS SFILQWTNVP TMFFLSAGAV SASCAFLYFC LEDSIKPDAS MVHRQAREIF
RLSHLCELLR TFFKKRSSYD RGIVWLTISI GVITVLGAGG GTVFFLYTRR QFGWTIQEFT
IWQAVELLSI VAGNVIGISV LKTLLKLPDI WLALLSVLNY SLDALIKGLA RQGWELYLAT
GITPLKATEG AALMAICSSI IPSSEIAKFY SIAMAMTNTV SLASAPLFTY IYNATVATAP
QVFNFVSSGI FSLNVVLVGV IAVLLRKRRK AQRSKSGPKG NIVPTKTSRR EFEDEDIDSD
EELEKQQRKQ PEIDDDVAEL ETTQDKRIRL AKQYLRQVQE EEQERDDYAD ESELASGMAR
TLKASYLSAT GKSHRTLGGK YTGYELTKAV SFHWKKQRLS PTCCALSADD AFLYVGCKSG
WVVRWNVKLK QRTACFQATK SVIHSIAVSH DMKYLVVADG TEEIKVLDGV SLVQLNTLKG
HSKPVTGVVF RLNSYQLFSC SADRTVKVWS LDEMVYIETL YGHQSQISGI DALSLERIVT
SGGMDQTLRI WKVAEESQLV FNSIAEDFSA VKFVSNDLFV SGSVEGSFSL WSSGKKKPLH
RIKLAHGEQD PGHPNWISAV GVLSNSDIVA SGSCDGTVRV WKLANKRHTI QPLLQIPVEG
FVNAIEFTSD GRFLVVAVGQ EHRLGRWWTL RNTKNQILMI PLSIEA
//
