ID   A0A182M3C0_9DIPT        Unreviewed;       681 AA.
AC   A0A182M3C0;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Methyltransferase type 11 domain-containing protein {ECO:0000259|Pfam:PF08241};
OS   Anopheles culicifacies.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles; culicifacies species complex.
OX   NCBI_TaxID=139723 {ECO:0000313|EnsemblMetazoa:ACUA008433-PA, ECO:0000313|Proteomes:UP000075883};
RN   [1] {ECO:0000313|Proteomes:UP000075883}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A-37 {ECO:0000313|Proteomes:UP000075883};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles culicifacies species A.";
RL   Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:ACUA008433-PA}
RP   IDENTIFICATION.
RC   STRAIN=A-37 {ECO:0000313|EnsemblMetazoa:ACUA008433-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   EMBL; AXCM01007175; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A182M3C0; -.
DR   STRING; 139723.A0A182M3C0; -.
DR   EnsemblMetazoa; ACUA008433-RA; ACUA008433-PA; ACUA008433.
DR   VEuPathDB; VectorBase:ACUA008433; -.
DR   OrthoDB; 179741at2759; -.
DR   Proteomes; UP000075883; Unassembled WGS sequence.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR   InterPro; IPR013216; Methyltransf_11.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR12176:SF78; EEF1A LYSINE AND N-TERMINAL METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR12176; SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN; 1.
DR   Pfam; PF08241; Methyltransf_11; 1.
DR   Pfam; PF01564; Spermine_synth; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          53..158
FT                   /note="Methyltransferase type 11"
FT                   /evidence="ECO:0000259|Pfam:PF08241"
SQ   SEQUENCE   681 AA;  75455 MW;  F730823A2601EB3D CRC64;
     MNLLPKTTAD FGSTEYWNAF FRKRGKHAFE WYGEYPELCD QLHQYIKPKD EILVVGCGNS
     KLSMDLYDVG FKKITNIDIS PVVIKQMQEA NRSTRPEMTW NQMDATAMSF PDESFSVVLD
     KGTLDALFTD ESTAVVTVVQ KYFTEIGRVL RAAGRYVCIS LLQEHILRKL VDHFPAAHFM
     LRIVRCPEAG KGNGSEDSVG ADGSSLVVFA IVATKLKNIP MRILELGLAG NHIERIQRPE
     ELLAGVAAAQ KAAMVCNGLA RGSIAGMAEV SLDLFAPSAK ERPRYTIHVL DQAPKRGNGK
     YAAFIVPQGR ETEWLFATPA GRRKLQESAK FDRLAIVTLH RGHVYNNLEA VKTELAESVK
     SLAPNGLQGA SIPYLSIGAE VGRRETIHTG RSELSGEYVV EEIAGENGRL FRRLVFLANQ
     SVVQSEAALK MARVRGSRTA QKVIDPGYLA CQHHLFMTVG VQLAANMTNA PGTSNNCPVA
     VVGLGGGGLC TFIRECLKQT TITAVEIDPE IEQIAVKYFG LTLDQRLRVV IADGIQFLAD
     EAARESHYSA LLFDVDSKDP TVGMSCPPAA FLEQAVLTNV RKLIGEKGLF VLNLVCRNES
     LRDTTVESLK RTFRYVLSYQ LEEDVNEIFY CTDNERLKDV SNWQDLLRTA ADDVNKLARK
     EKLTHEQELV DISDFITALK I
//